Publications by authors named "Curt R Freed"

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Persistent dyskinesias in patients with fetal tissue transplantation for Parkinson disease.
Paul E Greene, Stanley Fahn, David Eidelberg, Kimberly B Bjugstad, Robert E Breeze, Curt R Freed

NPJ Parkinsons Dis· April 2021

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Running wheel exercise reduces α-synuclein aggregation and improves motor and cognitive function in a transgenic mouse model of Parkinson's disease.
Wenbo Zhou, Jessica Cummiskey Barkow, Curt R Freed

PLoS One· January 2018

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Re-Cloning the N27 Dopamine Cell Line to Improve a Cell Culture Model of Parkinson's Disease.
Lu Gao, Wenbo Zhou, Breanna Symmes, Curt R Freed

PLoS One· August 2017

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DJ-1 Modulates Nuclear Erythroid 2-Related Factor-2-Mediated Protection in Human Primary Alveolar Type II Cells in Smokers.
Karim Bahmed, Elise M Messier, Wenbo Zhou, Rubin M Tuder, Curt R Freed

Am J Respir Cell Mol Biol· September 2016

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A nerve guidance conduit with topographical and biochemical cues: potential application using human neural stem cells.
Phillip M Jenkins, Melissa R Laughter, David J Lee, Young M Lee, Curt R Freed

Nanoscale Res Lett· December 2015

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A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity.
Rui Xiong, Wenbo Zhou, David Siegel, Russell R A Kitson, Curt R Freed

Mol Pharmacol· December 2015

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Substantial Differentiation of Human Neural Stem Cells Into Motor Neurons on a Biomimetic Polyurea.
Donghwa Yun, Young M Lee, Melissa R Laughter, Curt R Freed, Daewon Park

Macromol Biosci· September 2015

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Biomimetic poly(serinol hexamethylene urea) for promotion of neurite outgrowth and guidance.
Donghwa Yun, Amin Famili, Young Mook Lee, Phillip M Jenkins, Curt R Freed

J Biomater Sci Polym Ed· August 2014

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Human sensory neurons derived from induced pluripotent stem cells support varicella-zoster virus infection.
Katherine S Lee, Wenbo Zhou, Jonah J Scott-McKean, Kaitlin L Emmerling, Guang-yun Cai, Curt R Freed

PLoS One· July 2013

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Transplantation.
Curt R Freed, W Michael Zawada, Maureen Leehey, Wenbo Zhou, Robert E Breeze

Handb Clin Neurol· October 2012

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Dopamine cell transplantation for Parkinson's disease: the importance of controlled clinical trials.
Curt R Freed, Wenbo Zhou, Robert E Breeze

Neurotherapeutics· October 2011

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Phenylbutyrate up-regulates the DJ-1 protein and protects neurons in cell culture and in animal models of Parkinson disease.
Wenbo Zhou, Kathryn Bercury, Jessica Cummiskey, Nancy Luong, Jacob Lebin, Curt R Freed

J Biol Chem· April 2011

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Pallidal neuronal discharge in Parkinson's disease following intraputamenal fetal mesencephalic allograft.
R Mark Richardson, Curt R Freed, Shoichi A Shimamoto, Philip A Starr

J Neurol Neurosurg Psychiatry· March 2011

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Embryonic stem cells with GFP knocked into the dopamine transporter yield purified dopamine neurons in vitro and from knock-in mice.
Wenbo Zhou, Young Mook Lee, Vanessa C Guy, Curt R Freed

Stem Cells· December 2009

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Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells.
Wenbo Zhou, Curt R Freed

Stem Cells· November 2009

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Noggin enhances dopamine neuron production from human embryonic stem cells and improves behavioral outcome after transplantation into Parkinsonian rats.
Shunmei Chiba, Young Mook Lee, Wenbo Zhou, Curt R Freed

Stem Cells· November 2008

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Placebo response in Parkinson's disease: comparisons among 11 trials covering medical and surgical interventions.
Christopher G Goetz, Joanne Wuu, Michael P McDermott, Charles H Adler, Stanley Fahn, Curt R Freed

Mov Disord· April 2008

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Transgenic mice overexpressing tyrosine-to-cysteine mutant human alpha-synuclein: a progressive neurodegenerative model of diffuse Lewy body disease.
Wenbo Zhou, Julie B Milder, Curt R Freed

J Biol Chem· April 2008

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DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity.
Wenbo Zhou, Curt R Freed

J Biol Chem· December 2005

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Characterization of the Bex gene family in humans, mice, and rats.
Enrique Alvarez, Wenbo Zhou, Samir E Witta, Curt R Freed

Gene· August 2005

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Nectin-1/HveC Mediates herpes simplex virus type 1 entry into primary human sensory neurons and fibroblasts.
Scott A Simpson, Michael D Manchak, Elizabeth J Hager, Claude Krummenacher, J Charles Whitbeck, Curt R Freed

J Neurovirol· April 2005

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Generation of tyrosine hydroxylase positive neurons from human embryonic stem cells after coculture with cellular substrates and exposure to GDNF.
Kimberley A Buytaert-Hoefen, Enrique Alvarez, Curt R Freed

Stem Cells· March 2005

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Rapid purification and mass spectrometric characterization of mitochondrial NADH dehydrogenase (Complex I) from rodent brain and a dopaminergic neuronal cell line.
Birgit Schilling, Srinivas Bharath M M, Richard H Row, James Murray, Michael P Cusack, Curt R Freed

Mol Cell Proteomics· January 2005

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Preoperative response to levodopa is the best predictor of transplant outcome.
Curt R Freed, Robert E Breeze, Stanley Fahn, David Eidelberg

Ann Neurol· June 2004

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Reaction time and movement time after embryonic cell implantation in Parkinson disease.
Paul H Gordon, Qiping Yu, Clifford Qualls, Hal Winfield, Sandra Dillon, Curt R Freed

Arch Neurol· June 2004

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