Publications by authors named "Cynthia Burrows"

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APE1 Activity is Controlled by Non-G-Quadruplex Conformations in Single- and Double-Stranded G-Quadruplex Constructs.
Brianna L Trabucco, Aaron M Fleming, Cynthia J Burrows

Chemistry· December 2025

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Nanopore sequencing reveals operon-specific ribosome remodeling accompanying naphthyridone resistance in .
Dionysius W Copoulos, Kelly T Hughes, Fabienne F Chevance, Cynthia J Burrows, Aaron M Fleming

bioRxiv· December 2025

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RNA Oxidative Damage by the Iron-Fenton Reaction is Influenced by Bicarbonate Concentration and Ligand Strength.
Justin C Dingman, Aaron M Fleming, Cynthia J Burrows

Chem Res Toxicol· November 2025

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Telomeric DNA damage landscapes distinguish oxidative from inflammatory cellular stress.
Aaron M Fleming, Cynthia J Burrows

Nucleic Acids Res· November 2025

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Why the ROS matters: One-electron oxidants focus DNA damage and repair on G-quadruplexes for gene regulation.
Aaron M Fleming, Cynthia J Burrows

DNA Repair (Amst)· January 2025

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CO protects cells from iron-Fenton oxidative DNA damage in and humans.
Aaron M Fleming, Justin C Dingman, Cynthia J Burrows

Proc Natl Acad Sci U S A· December 2024

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Apurinic/Apyrimidinic Endodeoxyribonuclease 1 modulates RNA G-quadruplex folding of miR-92b and controls its expression in cancer cells.
Alessia Bellina, Matilde Clarissa Malfatti, Gilmar Salgado, Aaron M Fleming, Giulia Antoniali, Cynthia J Burrows

Proc Natl Acad Sci U S A· November 2024

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CO protects cells from iron-Fenton oxidative DNA damage in E. coli and humans.
Aaron M Fleming, Justin C Dingman, Cynthia J Burrows

bioRxiv· August 2024

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DNA Damage Accelerates G-Quadruplex Folding in a Duplex-G-Quadruplex-Duplex Context.
Aaron M Fleming, Brandon Leonel Guerra Castañaza Jenkins, Bethany A Buck, Cynthia J Burrows

J Am Chem Soc· April 2024

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Nanopore Direct RNA Sequencing for Modified Uridine Nucleotides Yields Signals Dependent on the Physical Properties of the Modified Base.
Aaron M Fleming, Justin C Dingman, Yizhou Wu, Spencer S Hoon, Cynthia J Burrows

Isr J Chem· April 2024

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DNA Damage Accelerates G-Quadruplex Folding in a Duplex-G-Quadruplex-Duplex Context.
Aaron M Fleming, Brandon Leonel Guerra Castañaza Jenkins, Bethany A Buck, Cynthia J Burrows

bioRxiv· January 2024

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NEIL3 promoter G-quadruplex with oxidatively modified bases shows magnesium-dependent folding that stalls polymerase bypass.
Aaron M Fleming, Carla A Omaga, Cynthia J Burrows

Biochimie· November 2023

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Advantages and challenges associated with bisulfite-assisted nanopore direct RNA sequencing for modifications.
Aaron M Fleming, Judy Zhu, Vilhelmina K Done, Cynthia J Burrows

RSC Chem Biol· November 2023

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Direct Nanopore Sequencing for the 17 RNA Modification Types in 36 Locations in the Ribosome Enables Monitoring of Stress-Dependent Changes.
Aaron M Fleming, Praneeth Bommisetti, Songjun Xiao, Vahe Bandarian, Cynthia J Burrows

ACS Chem Biol· October 2023

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Bisulfite and Nanopore Sequencing for Pseudouridine in RNA.
Cynthia J Burrows, Aaron M Fleming

Acc Chem Res· October 2023

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DNA modifications walk a fine line between epigenetics and mutagenesis.
Aaron M Fleming, Cynthia J Burrows

Nat Rev Mol Cell Biol· July 2023

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Sequencing for oxidative DNA damage at single-nucleotide resolution with click-code-seq v2.0.
Songjun Xiao, Aaron M Fleming, Cynthia J Burrows

Chem Commun (Camb)· July 2023

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Promoters telomeres: AP-endonuclease 1 interactions with abasic sites in G-quadruplex folds depend on topology.
Shereen A Howpay Manage, Judy Zhu, Aaron M Fleming, Cynthia J Burrows

RSC Chem Biol· April 2023

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Best Practices for Using AI When Writing Scientific Manuscripts.
Jillian M Buriak, Deji Akinwande, Natalie Artzi, C Jeffrey Brinker, Cynthia Burrows

ACS Nano· March 2023

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Nanopore sequencing for N1-methylpseudouridine in RNA reveals sequence-dependent discrimination of the modified nucleotide triphosphate during transcription.
Aaron M Fleming, Cynthia J Burrows

Nucleic Acids Res· February 2023

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Second Harmonic Generation Interrogation of the Endonuclease APE1 Binding Interaction with G-Quadruplex DNA.
Aaron M Fleming, Renee Tran, Carla A Omaga, Shereen A Howpay Manage, Cynthia J Burrows

Anal Chem· November 2022

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Fluorophore-mediated Photooxidation of the Guanine Heterocycle.
Aaron M Fleming, Songjun Xiao, Michael B Chabot, Cynthia J Burrows

J Phys Org Chem· November 2022

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Insights into the 5-Carboxamido-5-Formamido-2-Iminohydantoin Structural Isomerization Equilibria.
Michael B Chabot, Aaron M Fleming, Cynthia J Burrows

J Org Chem· September 2022

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Cysteine Oxidation to Sulfenic Acid in APE1 Aids G-Quadruplex Binding While Compromising DNA Repair.
Shereen A Howpay Manage, Aaron M Fleming, Hsiao-Nung Chen, Cynthia J Burrows

ACS Chem Biol· September 2022

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Pseudouridine and N1-Methylpseudouridine Display pH-Independent Reaction Rates with Bisulfite Yielding Ribose Adducts.
Aaron M Fleming, Songjun Xiao, Cynthia J Burrows

Org Lett· August 2022

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