Publications by authors named "Cyrus Mehta"

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Graph Based, Adaptive, Multiarm, Multiple Endpoint, Two-Stage Designs.
Cyrus Mehta, Ajoy Mukhopadhyay, Martin Posch

Stat Med· December 2025

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Peroneal Nerve Palsy After a Minimally Displaced Weber B Fibula Fracture: A Rare Case of Extensor Retinaculum Syndrome.
William Collins, Nikolas Drobetz, Cyrus Mehta

Foot Ankle Orthop· October 2025

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A Comparison of Two Methods for Adaptive Multi-Arm Two-Stage Design.
Cyrus Mehta, Martin Kappler

Stat Med· July 2025

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Testing One Primary and Two Secondary Endpoints in a Two-Stage Group Sequential Trial With Extensions.
Ajit C Tamhane, Dong Xi, Cyrus R Mehta, Alexander Romanenko, Jiangtao Gou

Stat Med· February 2025

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Pathophysiological Sex Differences in Heart Failure Progression After Acute Coronary Syndrome: Insights From the EXAMINE Trial.
Amir Razaghizad, Haya Aziz, Guang K Zhang, João Pedro Ferreira, William B White, Cyrus R Mehta

J Card Fail· June 2024

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Power Considerations in Designing and Interpreting Adaptive Clinical Trials.
Rui Wang, Cyrus Mehta

NEJM Evid· January 2024

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External validation and extension of the TIMI risk score for heart failure in diabetes for patients with recent acute coronary syndrome: An analysis of the EXAMINE trial.
Amir Razaghizad, Abhinav Sharma, Jiayi Ni, João Pedro Ferreira, William B White, Cyrus R Mehta

Diabetes Obes Metab· January 2023

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Economic Evaluation of Cost and Time Required for a Platform Trial vs Conventional Trials.
Jay J H Park, Behnam Sharif, Ofir Harari, Louis Dron, Anna Heath, Cyrus Mehta

JAMA Netw Open· July 2022

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A simulation-based comparison of estimation methods for adaptive and classical group sequential clinical trials.
Bryan S Nelson, Lingyun Liu, Cyrus Mehta

Pharm Stat· May 2022

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Optimal adaptive promising zone designs.
Cyrus Mehta, Apurva Bhingare, Lingyun Liu, Pralay Senchaudhuri

Stat Med· May 2022

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Blood and Urine Biomarkers Predicting Worsening Kidney Function in Patients with Type 2 Diabetes Post-Acute Coronary Syndrome: An Analysis from the EXAMINE Trial.
João Pedro Ferreira, Patrick Rossignol, George Bakris, Cyrus Mehta, William B White

Am J Nephrol· March 2022

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Robust group sequential designs for trials with survival endpoints and delayed response.
Pranab Ghosh, Robin Ristl, Franz König, Martin Posch, Christopher Jennison, Cyrus Mehta

Biom J· February 2022

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Influence of sex, age and race on coronary and heart failure events in patients with diabetes and post-acute coronary syndrome.
Xavier Rossello, João Pedro Ferreira, Francisca Caimari, Zohra Lamiral, Abhinav Sharma, Cyrus Mehta

Clin Res Cardiol· October 2021

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Body weight changes in patients with type 2 diabetes and a recent acute coronary syndrome: an analysis from the EXAMINE trial.
João Pedro Ferreira, Patrick Rossignol, George Bakris, Cyrus Mehta, William B White

Cardiovasc Diabetol· September 2021

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Multi-proteomic approach to predict specific cardiovascular events in patients with diabetes and myocardial infarction: findings from the EXAMINE trial.
João Pedro Ferreira, Abhinav Sharma, Cyrus Mehta, George Bakris, Patrick Rossignol

Clin Res Cardiol· July 2021

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Red cell distribution width in patients with diabetes and myocardial infarction: An analysis from the EXAMINE trial.
João Pedro Ferreira, Zohra Lamiral, George Bakris, Cyrus Mehta, William B White

Diabetes Obes Metab· July 2021

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REDUCE-IT INTERIM: accumulation of data across prespecified interim analyses to final results.
Brian Olshansky, Deepak L Bhatt, Michael Miller, Ph Gabriel Steg, Eliot A Brinton, Cyrus Mehta

Eur Heart J Cardiovasc Pharmacother· May 2021

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Gaining Efficiency in Clinical Trials With Cardiac Biomarkers: JACC Review Topic of the Week.
James L Januzzi, John M Canty, Saumya Das, Christopher R DeFilippi, Gary A Gintant, Cyrus Mehta

J Am Coll Cardiol· April 2021

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Timing of randomization after an acute coronary syndrome in patients with type 2 diabetes mellitus.
Malik Elharram, Abhinav Sharma, William White, George Bakris, Patrick Rossignol, Cyrus Mehta

Am Heart J· November 2020

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Alogliptin after acute coronary syndrome in patients with type 2 diabetes: a renal function stratified analysis of the EXAMINE trial.
João Pedro Ferreira, Cyrus Mehta, Abhinav Sharma, Steven E Nissen, Patrick Rossignol

BMC Med· June 2020

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Adaptive multiarm multistage clinical trials.
Pranab Ghosh, Lingyun Liu, Cyrus Mehta

Stat Med· April 2020

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Optimal promising zone designs.
Samuel T Hsiao, Lingyun Liu, Cyrus R Mehta

Biom J· September 2019

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Fasiglifam-Induced Liver Injury in Patients With Type 2 Diabetes: Results of a Randomized Controlled Cardiovascular Outcomes Safety Trial.
Venu Menon, A Michael Lincoff, Stephen J Nicholls, Susan Jasper, Kathy Wolski, Cyrus R Mehta

Diabetes Care· December 2018

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Average Clinician-Measured Blood Pressures and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Ischemic Heart Disease in the EXAMINE Trial.
William B White, Fatima Jalil, William C Cushman, George L Bakris, Richard Bergenstal, Cyrus Mehta

J Am Heart Assoc· October 2018

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Reassessing the Role of Surrogate End Points in Drug Development for Heart Failure.
Stephen J Greene, Robert J Mentz, Mona Fiuzat, Javed Butler, Scott D Solomon, Cyrus Mehta

Circulation· September 2018

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