Publications by authors named "D Rotticci"

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Design and synthesis of β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors with in vivo brain reduction of β-amyloid peptides.
Britt-Marie Swahn, Karin Kolmodin, Sofia Karlström, Stefan von Berg, Peter Söderman, Didier Rotticci

J Med Chem· November 2012

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Potent and orally efficacious benzothiazole amides as TRPV1 antagonists.
Yevgeni Besidski, William Brown, Johan Bylund, Michael Dabrowski, Sophie Dautrey, Didier Rotticci

Bioorg Med Chem Lett· October 2012

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First and second generation γ-secretase modulators (GSMs) modulate amyloid-β (Aβ) peptide production through different mechanisms.
Tomas Borgegard, Anders Juréus, Fredrik Olsson, Susanne Rosqvist, Alan Sabirsh, Didier Rotticci

J Biol Chem· April 2012

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Sulfonimidamides as sulfonamides bioisosteres: rational evaluation through synthetic, in vitro, and in vivo studies with γ-secretase inhibitors.
Fernando Sehgelmeble, Juliette Janson, Colin Ray, Susanne Rosqvist, Susanne Gustavsson, Didier Rotticci

ChemMedChem· March 2012

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Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacy.
Britt-Marie Swahn, Jörg Holenz, Jacob Kihlström, Karin Kolmodin, Johan Lindström, Didier Rotticci

Bioorg Med Chem Lett· March 2012

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