Publications by authors named "DS Thomson"

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Discovery and optimization of pyrazole amides as antagonists of CCR1.
Christian Harcken, Christopher Sarko, Can Mao, John Lord, Brian Raudenbush, David S Thomson

Bioorg Med Chem Lett· February 2019

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Selective CB2 receptor agonists. Part 2: Structure-activity relationship studies and optimization of proline-based compounds.
Doris Riether, Renee Zindell, Lifen Wu, Raj Betageri, James E Jenkins, David S Thomson

Bioorg Med Chem Lett· February 2015

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Selective CB2 receptor agonists. Part 1: the identification of novel ligands through computer-aided drug design (CADD) approaches.
Eugene R Hickey, Renee Zindell, Pier F Cirillo, Lifen Wu, Monika Ermann, David S Thomson

Bioorg Med Chem Lett· February 2015

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Selective CB2 receptor agonists. Part 3: the optimization of a piperidine-based series that demonstrated efficacy in an in vivo neuropathic pain model.
Alessandra Bartolozzi, Pier Francesco Cirillo, Angela K Berry, Eugene R Hickey, David S Thomson

Bioorg Med Chem Lett· February 2015

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Synthesis, SAR, and series evolution of novel oxadiazole-containing 5-lipoxygenase activating protein inhibitors: discovery of 2-[4-(3-{(r)-1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-1-cyclopropyl-ethyl}-[1,2,4]oxadiazol-5-yl)-pyrazol-1-yl]-N,N-dimethyl-acetamide (BI 665915).
Hidenori Takahashi, Doris Riether, Alessandra Bartolozzi, Todd Bosanac, Valentina Berger, David S Thomson

J Med Chem· February 2015

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Optimization of drug-like properties of nonsteroidal glucocorticoid mimetics and identification of a clinical candidate.
Christian Harcken, Doris Riether, Pingrong Liu, Hossein Razavi, Usha Patel, David S Thomson

ACS Med Chem Lett· December 2014

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Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: conformation, selectin binding, and biological activity.
Charalampos G Panagos, Derek S Thomson, Claire Moss, Adam D Hughes, Maeve S Kelly

J Biol Chem· October 2014

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Discovery of a potent and dissociated non-steroidal glucocorticoid receptor agonist containing an alkyl carbinol pharmacophore.
Hossein Razavi, Doris Riether, Christian Harcken, Jörg Bentzien, Roger M Dinallo, David S Thomson

Bioorg Med Chem Lett· April 2014

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Identification of highly efficacious glucocorticoid receptor agonists with a potential for reduced clinical bone side effects.
Christian Harcken, Doris Riether, Daniel Kuzmich, Pingrong Liu, Raj Betageri, David S Thomson

J Med Chem· February 2014

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Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores.
Raj Betageri, Thomas Gilmore, Daniel Kuzmich, Thomas M Kirrane, Jörg Bentzien, David S Thomson

Bioorg Med Chem Lett· November 2011

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1,4-Diazepane compounds as potent and selective CB2 agonists: optimization of metabolic stability.
Doris Riether, Lifen Wu, Pier F Cirillo, Angela Berry, Edward R Walker, David S Thomson

Bioorg Med Chem Lett· April 2011

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Nonsteroidal dissociated glucocorticoid agonists containing azaindoles as steroid A-ring mimetics.
Doris Riether, Christian Harcken, Hossein Razavi, Daniel Kuzmich, Thomas Gilmore, David S Thomson

J Med Chem· September 2010

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Intravenous leiomyomatosis with intracardiac extension: first reported case in Australia.
Taranpreet Singh, Philip M Lamont, Geoffrey R Otton, Duncan S Thomson

Heart Lung Circ· January 2010

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Simplified cerebral protection using unilateral antegrade cerebral perfusion and moderate hypothermic circulatory arrest.
Satoshi Numata, Duncan S Thomson, Peng Seah, Taranpreet Singh

Heart Lung Circ· October 2009

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Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors.
Younes Bekkali, David S Thomson, Raj Betageri, Michel J Emmanuel, Ming-Hong Hao

Bioorg Med Chem Lett· May 2007

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Alpha-methyltryptamine sulfonamide derivatives as novel glucocorticoid receptor ligands.
Daniel R Marshall, Gus Rodriguez, David S Thomson, Richard Nelson, Allison Capolina

Bioorg Med Chem Lett· January 2007

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Quinol-4-ones as steroid A-ring mimetics in nonsteroidal dissociated glucocorticoid agonists.
John Regan, Thomas W Lee, Renée M Zindell, Younes Bekkali, Jörg Bentzien, David S Thomson

J Med Chem· December 2006

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Observations of mercury-containing aerosols.
D M Murphy, P K Hudson, l D S Thomson, P J Sheridan, J C Wilson

Environ Sci Technol· May 2006

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Mitral valve replacement in a severely calcified posterior annulus: a novel technique.
Wail O El-Amin, Duncan S Thomson

Heart Lung Circ· April 2006

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A concise asymmetric route for the synthesis of a novel class of glucocorticoid mimetics containing a trifluoromethyl-substituted alcohol.
Thomas W Lee, John R Proudfoot, David S Thomson

Bioorg Med Chem Lett· February 2006

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Trifluoromethyl group as a pharmacophore: effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand.
Raj Betageri, Yan Zhang, Renee M Zindell, Daniel Kuzmich, Thomas M Kirrane, David S Thomson

Bioorg Med Chem Lett· November 2005

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Measurements of the concentration and composition of nuclei for cirrus formation.
P J DeMott, D J Cziczo, A J Prenni, D M Murphy, S M Kreidenweis, D S Thomson

Proc Natl Acad Sci U S A· December 2003

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A new technique for repair of atrioventricular disruption complicating mitral valve replacement.
Rosauro Mejia, Duncan S Thomson

Ann Thorac Surg· June 2003

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Design and synthesis of dipeptide nitriles as reversible and potent Cathepsin S inhibitors.
Yancey D Ward, David S Thomson, Leah L Frye, Charles L Cywin, Tina Morwick

J Med Chem· December 2002

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Median sternotomy and extended left anterior thoracotomy for repair of traumatic aortic transection with ruptured right atrium.
Dong Kang, Duncan S Thomson, Kiyoshi Doi, Allen N James

Ann Thorac Surg· December 2002

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