Publications by authors named "Dacheng Fan"

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Uncovering the rewired IAP-JAK regulatory axis as an immune-dependent vulnerability of LKB1-mutant lung cancer.
Changfa Shu, Jianfeng Li, Jin Rui, Dacheng Fan, Qiankun Niu

Nat Commun· March 2025

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OGA mutant aberrantly hydrolyzes O-GlcNAc modification from PDLIM7 to modulate p53 and cytoskeleton in promoting cancer cell malignancy.
Chia-Wei Hu, Ao Wang, Dacheng Fan, Matthew Worth, Zhengwei Chen

Proc Natl Acad Sci U S A· June 2024

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TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS.
Danielle Cicka, Qiankun Niu, Min Qui, Kun Qian, Eric Miller, Dacheng Fan, Stefan G Sarafianos

J Mol Cell Biol· August 2023

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Cancer-derived mutation in the OGA stalk domain promotes cell malignancy through dysregulating PDLIM7 and p53.
Chia-Wei Hu, Ao Wang, Dacheng Fan, Matthew Worth, Zhengwei Chen

Res Sq· March 2023

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Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells.
Changfa Shu, Xi Zheng, Alafate Wuhafu, Danielle Cicka, Sean Doyle, Dacheng Fan

Acta Pharmacol Sin· September 2022

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Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
Xiulei Mo, Qiankun Niu, Andrey A Ivanov, Yiu Huen Tsang, Cong Tang, Dacheng Fan

Cell· May 2022

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Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer.
Xuan Yang, Dacheng Fan, Aidan Henry Troha, Hyunjun Max Ahn, Kun Qian

Bioorg Med Chem· September 2021

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Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe.
Adam Kositzke, Dacheng Fan, Ao Wang, Hao Li, Matthew Worth

Int J Biol Macromol· February 2021

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Targeted covalent inhibition of O-GlcNAc transferase in cells.
Matthew Worth, Chia-Wei Hu, Hao Li, Dacheng Fan, Arielis Estevez

Chem Commun (Camb)· October 2019

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Aglycone Ebselen and β-d-Xyloside Primed Glycosaminoglycans Co-contribute to Ebselen β-d-Xyloside-Induced Cytotoxicity.
Yang Tang, Siqi Zhang, Yajing Chang, Dacheng Fan, Ariane De Agostini

J Med Chem· April 2018

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Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.
Chia-Wei Hu, Matthew Worth, Dacheng Fan, Baobin Li, Hao Li, Xiaofang Zhong

Nat Chem Biol· December 2017

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Distributive O-GlcNAcylation on the Highly Repetitive C-Terminal Domain of RNA Polymerase II.
Lei Lu, Dacheng Fan, Chia-Wei Hu, Matthew Worth, Zhi-Xiong Ma

Biochemistry· February 2016

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Exploring stereoselectivity of 3-indolyl cyclopent[b]indoles: a parallel synthesis and anti-EGFR study on human cancer cells.
Dacheng Fan, Weizhi Sun, Peiju Qiu, Zhiyong Wu, Yantuan Li

Eur J Med Chem· March 2014

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