Publications by authors named "DaeSik Kim"

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AIM2 drives inflammatory cell death and monkeypox pathogenesis.
Jueun Oh, Yun-Ho Hwang, Jihye Lee, Cheong Seok, SuHyeon Oh, Hye Yoon Kim, Hayeon Kim, Suhyun Kim, Dokeun Kim, Daesik Kim, You-Jin Kim

Cell Mol Immunol· December 2025

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Generation and ophthalmological characterization of oculocutaneous albinism type 1 pig models by selection-free genome editing.
Dongjin Oh, Cheong Seok, Hyun Woo Park, Soomin Park, Joohyeong Lee, Daesik Kim

Sci Rep· December 2025

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High-efficiency base editing for nuclear and mitochondrial DNA with an optimized DYW-like deaminase.
Jiyeon Kweon, Soomin Park, Mi Yeon Jeon, Kayeong Lim, Gayoung Jang, Naheun Kim, Daesik Kim, Yongsub Kim

Mol Ther· November 2025

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eVLP-Mediated Cas9 Delivery for Preventing IBMIR in Islet Transplantation.
Manju Shrestha, Yeonji Kim, Subin Park, Hu-Lin Jiang, Jae-Young Lee, Daesik Kim

Small· November 2025

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Engineered virus-like particle-assembled Vegfa-targeting Cas9 ribonucleoprotein treatment alleviates neovascularization in wet age-related macular degeneration.
Jun Wu, Hyewon Jang, Hyunjong Kwak, Minchae Son, Weiyan Jiang, Daesik Kim, Hyongbum Henry Kim, Jeong Hun Kim

Genome Biol· October 2025

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Single-Cell RNA Analysis Reveals Reduced Frequency and Activity of CXCR5 Atypical Memory B Cells in Islet Xenotransplantation Treated With Clinically Applicable Immunosuppressants Including Belimumab.
Yuji Lee, Ji Hwan Moon, Hyun Je Kim, Daesik Kim, Yong-Hee Kim, Jong-Min Kim

Xenotransplantation· September 2025

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Four germline POLH variants, including two found in skin tumors, impair DNA polymerase η function and cellular tolerance to UV radiation and cisplatin.
Jin-Kyung Hong, Mina Yeom, Hye-Yeon Hwang, Eunji Mun, Jae-Hyeon Woo, Yeho Kim, Daesik Kim

Chem Biol Interact· August 2025

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Engineered Sdd7 cytosine base editors with enhanced specificity.
Hye-Yeon Hwang, Minyoung Lee, Hwalin Yi, Cheong Seok, Kayeong Lim, Daesik Kim

Nat Commun· July 2025

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Epstein-Barr virus and multiple sclerosis: lesson learned to develop better nonhuman primate models.
Hai Duc Nguyen, Daesik Kim, Yong-Hee Kim, Erik Flemington, Gavin Giovannoni, Woong-Ki Kim

Exp Mol Med· June 2025

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Real-Time Monitoring of Cardiac Output Using Non-Invasive Impedance Cardiography in Dogs: A Pilot Study on Heartworm Extraction and Gastric Decompression.
Daesik Kim, Seol-Gi Park, Min Su Kim

Vet Sci· May 2025

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EBP1 potentiates amyloid β pathology by regulating γ-secretase.
Byeong-Seong Kim, Inwoo Hwang, Hyo Rim Ko, Young Kwan Kim, Hee Jin Kim, Yun Kyung Kim, Daesik Kim

Nat Aging· March 2025

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Immune cell-enriched single-cell RNA sequencing unveils the interplay between infiltrated CD8 T resident memory cells and choroid plexus epithelial cells in Alzheimer's disease.
Seong-Jun Kang, Yong-Hee Kim, Thuy Nguyen-Phuong, Yijoon Kim, Jin-Mi Oh, DaeSik Kim, Hyun Je Kim

J Neuroimmunol· January 2025

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In vivo adenine base editing rescues adrenoleukodystrophy in a humanized mouse model.
Ramu Gopalappa, MinYoung Lee, Globinna Kim, Eul Sik Jung, Hanahrae Lee, Su Jung Kim, Daesik Kim, Hyongbum Henry Kim

Mol Ther· July 2024

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Precise editing of pathogenic nucleotide repeat expansions in iPSCs using paired prime editor.
Hye-Yeon Hwang, Dongmin Gim, Hwalin Yi, Hyewon Jung, Jaecheol Lee, Daesik Kim

Nucleic Acids Res· June 2024

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CRISPR-based editing strategies to rectify complex genomic rearrangement linked to haploinsufficiency.
Hwalin Yi, Yejin Yun, Won Hoon Choi, Hye-Yeon Hwang, Ju Hyuen Cha, Daesik Kim

Mol Ther Nucleic Acids· June 2024

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Integrated NLRP3, AIM2, NLRC4, Pyrin inflammasome activation and assembly drive PANoptosis.
SuHyeon Oh, Jihye Lee, Jueun Oh, Gyoengju Yu, Haesun Ryu, Daesik Kim

Cell Mol Immunol· December 2023

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Interventional Heartworm Extraction in Two Dogs: The Clinical Application of Impedance Cardiography.
Daesik Kim, Seol-Gi Park, Minsu Kim

Animals (Basel)· October 2023

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β-arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4.
Ji Young Kim, Ji Hye Shin, Mi-Jeong Kim, Yeeun Kang, Ji Su Lee, Daesik Kim, Duk-Hwan Kim

Cell Death Dis· July 2023

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FFAR2 antagonizes TLR2- and TLR3-induced lung cancer progression via the inhibition of AMPK-TAK1 signaling axis for the activation of NF-κB.
Mi-Jeong Kim, Ji Young Kim, Ji Hye Shin, Yeeun Kang, Ji Su Lee, Daesik Kim, Duk-Hwan Kim

Cell Biosci· June 2023

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DNA double-strand break-free CRISPR interference delays Huntington's disease progression in mice.
Jung Hwa Seo, Jeong Hong Shin, Junwon Lee, Daesik Kim, Hye-Yeon Hwang, Hyongbum Henry Kim

Commun Biol· April 2023

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Selective-Area Growth Mechanism of GaN Microrods on a Plateau Patterned Substrate.
Min-Joo Ahn, Woo-Seop Jeong, Kyu-Yeon Shim, Seongho Kang, Hwayoung Kim, Dae-Sik Kim, Jaekyun Kim

Materials (Basel)· March 2023

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Targeted genomic translocations and inversions generated using a paired prime editing strategy.
Jiyeon Kweon, Hye-Yeon Hwang, Haesun Ryu, An-Hee Jang, Daesik Kim, Yongsub Kim

Mol Ther· January 2023

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Profiling Genome-Wide Specificity of dCpf1 Cytidine Base Editors Using Digenome-Seq.
Daesik Kim

Methods Mol Biol· January 2023

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Expanded targeting scope of LbCas12a variants allows editing of multiple oncogenic mutations.
Eunyoung Choi, Hye-Yeon Hwang, Eunji Kwon, Daesik Kim, Taeyoung Koo

Mol Ther Nucleic Acids· December 2022

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Horticultural Therapy for Improving the Work Performance and Interpersonal Relationships of Persons with Intellectual Disabilities.
Hyo-Jung Son, Dae-Sik Kim, Sin-Ae Park

Int J Environ Res Public Health· October 2022

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