Publications by authors named "Daisuke Ejima"

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SDS protein interactions.
Tsutomu Arakawa, Daisuke Ejima, Tomoto Ura, Teruo Akuta, Masamichi Oh-Ishi

Biophys Chem· January 2026

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Solubilization and refolding of inclusion bodies by detergents.
Tsutomu Arakawa, Teruo Akuta, Daisuke Ejima, Kouhei Tsumoto

Protein Expr Purif· December 2025

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Introducing arginine residues into scFv in CAR-T cells shows promising antitumor effects.
Shingo Maeta, Atsushi Fukunaga, Yuriko Egashira, Yasushi Akahori, Linan Wang, Daisuke Ejima

Mol Ther· December 2025

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Mini review for niche downstream processes.
Tsutomu Arakawa, Daisuke Ejima, Yui Tomioka, Chiaki Sakuma, Teruo Akuta

Protein Expr Purif· June 2025

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Spatiotemporal Control of Protein Refolding through Flash-Change Reaction Conditions.
Yuichi Nakahara, Tomoko Kawaguchi, Yutaka Matsuda, Yuta Endo, Masayo Date, Daisuke Ejima

Langmuir· April 2024

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Electrophoresis, a transport technology that transitioned from moving boundary method to zone method.
Tsutomu Arakawa, Masataka Nakagawa, Chiaki Sakuma, Yui Tomioka, Yasunori Kurosawa, Daisuke Ejima

Eur Biophys J· February 2024

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Non-Affinity Purification of Antibodies.
Tsutomu Arakawa, Yui Tomioka, Masataka Nakagawa, Chiaki Sakuma, Yasunori Kurosawa, Daisuke Ejima

Antibodies (Basel)· February 2023

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Mirror-image streptavidin with specific binding to L-biotin, the unnatural enantiomer.
Masatoshi Suganuma, Takuya Kubo, Kengo Ishiki, Kota Tanaka, Kouzou Suto, Daisuke Ejima

Sci Rep· June 2022

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Protein aggregation suppressor arginine as an effective mouth cleaning agent.
Keiko Ikeda, Daisuke Ejima, Tsutomu Arakawa, A Hajime Koyama

Int J Biol Macromol· February 2019

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Long-Term Stability and Reversible Thermal Unfolding of Antibody Structure at Low pH: Case Study.
Harumi Fukada, Kouhei Tsumoto, Tsutomu Arakawa, Daisuke Ejima

J Pharm Sci· November 2018

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Protein aggregation under high concentration/density state during chromatographic and ultrafiltration processes.
Tsutomu Arakawa, Daisuke Ejima, Teruo Akuta

Int J Biol Macromol· February 2017

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Heat-induced formation of myosin oligomer-soluble filament complex in high-salt solution.
Masato Shimada, Eisuke Takai, Daisuke Ejima, Tsutomu Arakawa, Kentaro Shiraki

Int J Biol Macromol· February 2015

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Alternative downstream processes for production of antibodies and antibody fragments.
Tsutomu Arakawa, Kouhei Tsumoto, Daisuke Ejima

Biochim Biophys Acta· November 2014

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Synergistic solubilization of porcine myosin in physiological salt solution by arginine.
Eisuke Takai, Shunsuke Yoshizawa, Daisuke Ejima, Tsutomu Arakawa, Kentaro Shiraki

Int J Biol Macromol· November 2013

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Refolding single-chain antibody (scFv) using lauroyl-L-glutamate as a solubilization detergent and arginine as a refolding additive.
Motonori Kudou, Daisuke Ejima, Haruna Sato, Ryosuke Yumioka, Tsutomu Arakawa

Protein Expr Purif· May 2011

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A novel protein refolding system using lauroyl-l-glutamate as a solubilizing detergent and arginine as a folding assisting agent.
Motonori Kudou, Ryosuke Yumioka, Daisuke Ejima, Tsutomu Arakawa, Kouhei Tsumoto

Protein Expr Purif· January 2011

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MEP HyperCel chromatography II: binding, washing and elution.
Tsutomu Arakawa, Mutsumi Futatsumori-Sugai, Kouhei Tsumoto, Yoshiko Kita, Haruna Sato, Daisuke Ejima

Protein Expr Purif· June 2010

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Screening of effective column rinse solvent for Protein-A chromatography.
Ryosuke Yumioka, Kouhei Tsumoto, Tsutomu Arakawa, Daisuke Ejima

Protein Expr Purif· April 2010

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The critical role of mobile phase composition in size exclusion chromatography of protein pharmaceuticals.
Tsutomu Arakawa, Daisuke Ejima, Tiansheng Li, John S Philo

J Pharm Sci· April 2010

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Non-denaturing solubilization of inclusion bodies.
Kouhei Tsumoto, Ryota Abe, Daisuke Ejima, Tsutomu Arakawa

Curr Pharm Biotechnol· April 2010

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Mobile phase containing arginine provides more reliable SEC condition for aggregation analysis.
Ryosuke Yumioka, Haruna Sato, Hiroshi Tomizawa, Yosuke Yamasaki, Daisuke Ejima

J Pharm Sci· February 2010

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Antiviral and virucidal activities of natural products.
Tsutomu Arakawa, Hisashi Yamasaki, Keiko Ikeda, Daisuke Ejima, Takeshi Naito

Curr Med Chem· January 2010

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Utilization of Arg-elution method for FLAG-tag based chromatography.
Mutsumi Futatsumori-Sugai, Ryota Abe, Masato Watanabe, Motonori Kudou, Tadashi Yamamoto, Daisuke Ejima

Protein Expr Purif· October 2009

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Stress-free chromatography: affinity chromatography.
Tsutomu Arakawa, Yoshiko Kita, Haruna Sato, Daisuke Ejima

Curr Pharm Biotechnol· June 2009

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Stress-free chromatography: IEC and HIC.
Tsutomu Arakawa, Yoshiko Kita, Daisuke Ejima

Curr Pharm Biotechnol· June 2009

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