Publications by authors named "Daisuke Watase"

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Menaquinone-4 inhibits the formation and vulnerability of atherosclerotic plaques in apolipoprotein E knockout mice by decreasing the uptake of the oxidized low-density lipoprotein in macrophages.
Ayano Yamada, Mitsuhisa Koga, Daisuke Watase, Mai Hazekawa, Masako Harada

Eur J Pharmacol· September 2025

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Menahydroquinone-4 may play a key role in regulating CCL5 expression induced by epidermal growth factor receptor inhibitors.
Shotaro Goto, Shuichi Setoguchi, Daisuke Watase, Hirofumi Yamakawa, Ayano Yamada

Sci Rep· December 2023

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Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption.
Mariko Hirano-Kusuda, Shuichi Setoguchi, Mitsuhisa Koga, Shotaro Goto, Ayano Yamada, Daisuke Watase

Pharm Res· May 2023

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Delivery of the reduced form of vitamin K to NIH/3T3 cells partially protects against rotenone induced cell death.
Erina Toki, Shotaro Goto, Shuichi Setoguchi, Kazuki Terada, Daisuke Watase

Sci Rep· November 2022

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Cationic ,-Dimethylglycine Ester Prodrug of 2-α-Tocotrienol Promotes Intestinal Absorption via Efficient Self-Micellization with Intrinsic Bile Acid Anion.
Daisuke Watase, Shuichi Setoguchi, Nami Nagata-Akaho, Shotaro Goto, Hirofumi Yamakawa

Molecules· April 2022

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Growth Inhibitory Effects of Ester Derivatives of Menahydroquinone-4, the Reduced Form of Vitamin K, on All-Trans Retinoic Acid-Resistant HL60 Cell Line.
Hirofumi Yamakawa, Shuichi Setoguchi, Shotaro Goto, Daisuke Watase, Kazuki Terada

Pharmaceutics· May 2021

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Ester derivatives of phyllohydroquinone effectively deliver the active form of vitamin K topically, owing to their non-photosensitivity.
Shotaro Goto, Shuichi Setoguchi, Nami Nagata-Akaho, Kazuki Terada, Daisuke Watase

Eur J Pharm Sci· December 2020

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Evaluation of photostability and phototoxicity of esterified derivatives of ubiquinol-10 and their application as prodrugs of reduced coenzyme Q for topical administration.
Shuichi Setoguchi, Nami Nagata-Akaho, Shotaro Goto, Hirofumi Yamakawa, Daisuke Watase

Biofactors· November 2020

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Atypical Antipsychotic Drug Ziprasidone Protects against Rotenone-Induced Neurotoxicity: An In Vitro Study.
Kazuki Terada, Ayumi Murata, Erina Toki, Shotaro Goto, Hirofumi Yamakawa, Daisuke Watase

Molecules· September 2020

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Novel Cationic Prodrug of Ubiquinol-10 Enhances Intestinal Absorption via Efficient Formation of Nanosized Mixed-Micelles with Bile Acid Anions.
Shuichi Setoguchi, Ryoji Hidaka, Nami Nagata-Akaho, Daisuke Watase, Mitsuhisa Koga

Molecules· January 2020

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Prodrugs for Skin Delivery of Menahydroquinone-4, an Active Form of Vitamin K, Could Overcome the Photoinstability and Phototoxicity of Vitamin K.
Shotaro Goto, Shuichi Setoguchi, Hirofumi Yamakawa, Daisuke Watase, Kazuki Terada

Int J Mol Sci· May 2019

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Antitumor Effects and Delivery Profiles of Menahydroquinone-4 Prodrugs with Ionic or Nonionic Promoiety to Hepatocellular Carcinoma Cells.
Shuichi Setoguchi, Daisuke Watase, Kazuhisa Matsunaga, Hirofumi Yamakawa, Shotaro Goto

Molecules· July 2018

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Effect of orally ingested diosgenin into diet on skin collagen content in a low collagen skin mouse model and its mechanism of action.
Akinori Haratake, Daisuke Watase, Shuichi Setoguchi, Nami Nagata-Akaho, Kazuhisa Matsunaga

Life Sci· April 2017

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Pharmacokinetics of Paradol Analogues Orally Administered to Rats.
Shuichi Setoguchi, Daisuke Watase, Nami Nagata-Akaho, Akinori Haratake, Kazuhisa Matsunaga

J Agric Food Chem· March 2016

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Menahydroquinone-4 Prodrug: A Promising Candidate Anti-Hepatocellular Carcinoma Agent.
Munechika Enjoji, Daisuke Watase, Kazuhisa Matsunaga, Mariko Kusuda, Nami Nagata-Akaho

Diseases· July 2015

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Enhanced antitumor effects of novel intracellular delivery of an active form of menaquinone-4, menahydroquinone-4, into hepatocellular carcinoma.
Shuichi Setoguchi, Daisuke Watase, Kazuhisa Matsunaga, Misa Matsubara, Yohei Kubo

Cancer Prev Res (Phila)· February 2015

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Relationship between the acyl chain length of paradol analogues and their antiobesity activity following oral ingestion.
Akinori Haratake, Daisuke Watase, Shuichi Setoguchi, Kazuki Terada, Kazuhisa Matsunaga

J Agric Food Chem· July 2014

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