Publications by authors named "Dale D O Martin"

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Reversion of heme-dependent metronidazole resistance in .
Lillia Louis, Firyal Ramzan, Dale D O Martin, Abiola O Olaitan

Microbiol Spectr· November 2025

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Micro-scale control of oligodendrocyte morphology and myelination by the intellectual disability-linked protein acyltransferase ZDHHC9.
Hey-Kyeong Jeong, Estibaliz Gonzalez-Fernandez, Ilan Crawley, Julia M Coakley, Jinha Hwang, Dale D O Martin

Elife· October 2025

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Altered Protein Palmitoylation as Disease Mechanism in Neurodegenerative Disorders.
Jakub Wlodarczyk, Raja Bhattacharyya, Kim Dore, Gary P H Ho, Dale D O Martin

J Neurosci· October 2024

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Protective Proteolysis in Huntington's Disease: Unraveling the Role of Post-Translational Myristoylation of Huntingtin in Autophagy.
Yasmeen Alshehabi, Dale D O Martin

J Huntingtons Dis· September 2024

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Fatty links between multisystem proteinopathy and small VCP-interacting protein.
Firyal Ramzan, Ashish Kumar, Fatima Abrar, Rachel A V Gray, Zurie E Campbell, Dale D O Martin

Cell Death Discov· August 2024

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Let's get fat: emergence of S-acylation as a therapeutic target in Huntington disease.
Dale D O Martin, Shaun S Sanders

Biochem Soc Trans· June 2024

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Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein A-I nanodisks for Huntington disease.
Nicholas S Caron, Amirah E-E Aly, Hailey Findlay Black, Dale D O Martin, Mandi E Schmidt

J Control Release· March 2024

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Delivery of mutant huntingtin-lowering antisense oligonucleotides to the brain by intranasally administered apolipoprotein A-I nanodisks.
Amirah E-E Aly, Nicholas S Caron, Hailey Findlay Black, Mandi E Schmidt, Christine Anderson, Dale D O Martin

J Control Release· August 2023

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Lost in traffic: consequences of altered palmitoylation in neurodegeneration.
Firyal Ramzan, Fatima Abrar, Gyana Gourab Mishra, Lucia Meng Qi Liao, Dale D O Martin

Front Physiol· May 2023

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Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage.
Fanny L Lemarié, Shaun S Sanders, Yen Nguyen, Dale D O Martin, Michael R Hayden

Front Physiol· January 2023

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Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity.
Fanny L Lemarié, Nicholas S Caron, Shaun S Sanders, Mandi E Schmidt, Yen T N Nguyen, Dale D O Martin

Neurobiol Dis· October 2021

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Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry.
Lucia M Q Liao, Rachel A V Gray, Dale D O Martin

J Vis Exp· April 2021

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Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance.
Dale D O Martin, Mandi E Schmidt, Yen T Nguyen, Nikola Lazic, Michael R Hayden

FASEB J· March 2019

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Identification of Novel Inhibitors of DLK Palmitoylation and Signaling by High Content Screening.
Dale D O Martin, Prasad S Kanuparthi, Sabrina M Holland, Shaun S Sanders, Hey-Kyeong Jeong

Sci Rep· March 2019

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Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease.
Dagmar E Ehrnhoefer, Dale D O Martin, Mandi E Schmidt, Xiaofan Qiu, Safia Ladha

Acta Neuropathol Commun· March 2018

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Neurodegeneration: Role of repeats in protein clearance.
Dale D O Martin, Michael R Hayden

Nature· May 2017

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Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers.
Shaun S Sanders, Dale D O Martin, Stefanie L Butland, Mathieu Lavallée-Adam, Diego Calzolari

PLoS Comput Biol· August 2015

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Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice.
Bibiana K Y Wong, Dagmar E Ehrnhoefer, Rona K Graham, Dale D O Martin, Safia Ladha

Neurobiol Dis· April 2015

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Post-translational myristoylation at the cross roads of cell death, autophagy and neurodegeneration.
Dale D O Martin, Michael R Hayden

Biochem Soc Trans· April 2015

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Autophagy in Huntington disease and huntingtin in autophagy.
Dale D O Martin, Safia Ladha, Dagmar E Ehrnhoefer, Michael R Hayden

Trends Neurosci· January 2015

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The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.
Stefanie L Butland, Shaun S Sanders, Mandi E Schmidt, Sean-Patrick Riechers, David T S Lin, Dale D O Martin

Hum Mol Genet· August 2014

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Identification of a post-translationally myristoylated autophagy-inducing domain released by caspase cleavage of huntingtin.
Dale D O Martin, Ryan J Heit, Megan C Yap, Michael W Davidson, Michael R Hayden

Hum Mol Genet· June 2014

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The Salmonella type III effector SspH2 specifically exploits the NLR co-chaperone activity of SGT1 to subvert immunity.
Amit P Bhavsar, Nat F Brown, Jan Stoepel, Marcel Wiermer, Dale D O Martin

PLoS Pathog· February 2014

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Regulation of co- and post-translational myristoylation of proteins during apoptosis: interplay of N-myristoyltransferases and caspases.
Maneka A Perinpanayagam, Erwan Beauchamp, Dale D O Martin, Jacky Y W Sim, Megan C Yap

FASEB J· February 2013

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Tandem reporter assay for myristoylated proteins post-translationally (TRAMPP) identifies novel substrates for post-translational myristoylation: PKCε, a case study.
Dale D O Martin, Chrisselle Y Ahpin, Ryan J Heit, Maneka A Perinpanayagam, Megan C Yap

FASEB J· January 2012

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