Publications by authors named "Dallas Flies"

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NC410, a bivalent LAIR-2 construct, remodels collagen in the tumor microenvironment and abrogates neutrophil-driven T cell suppression.
Thejaswini Giridharan, Sora Suzuki, Anm Nazmul H Khan, Qian Liu, Kristopher Attwood, Dallas Flies

J Immunol· September 2025

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Immune inhibitory receptor agonist therapeutics.
Rustin R Lovewell, Solomon Langermann, Dallas B Flies

Front Immunol· April 2025

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Editorial: Beyond PD-1: novel checkpoint receptors and ligands as targets for immunotherapy.
Jesse Haramati, Fabiola Solorzano-Ibarra, Dallas B Flies

Front Immunol· February 2025

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BCAM (basal cell adhesion molecule) protein expression in different tumor populations.
Sneha Burela, Mengni He, Ioannis P Trontzas, Niki Gavrielatou, Kurt A Schalper, Dallas B Flies

Discov Oncol· August 2024

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Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity.
Tianxiang Zhang, Weiwei Yu, Xiaoxiao Cheng, Jacky Yeung, Viviana Ahumada, Dallas B Flies

Sci Immunol· April 2024

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The FLRT3-UNC5B checkpoint pathway inhibits T cell-based cancer immunotherapies.
Kushal Prajapati, Chuan Yan, Qiqi Yang, Steven Arbitman, Daniel P Fitzgerald, Dallas B Flies

Sci Adv· March 2024

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Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice.
Akashdip Singh, Eline T A M Mommers-Elshof, Saskia V Vijver, J H Marco Jansen, Susanne Gonder, Dallas Flies

Cancer Immunol Immunother· January 2024

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LAIR-1 agonism as a therapy for acute myeloid leukemia.
Rustin R Lovewell, Junshik Hong, Subhadip Kundu, Carly M Fielder, Qianni Hu, Dallas B Flies

J Clin Invest· November 2023

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Regulation of tumor immunity and immunotherapy by the tumor collagen extracellular matrix.
Dallas B Flies, Solomon Langermann, Christina Jensen, Morten A Karsdal, Nicholas Willumsen

Front Immunol· September 2023

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Author Correction: Programmed death one homolog maintains the pool size of regulatory T cells by promoting their differentiation and stability.
Qi Wang, Jianwei He, Dallas B Flies, Liqun Luo, Lieping Chen

Sci Rep· July 2023

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Quantitative, Spatially Defined Expression of Leukocyte-associated Immunoglobulin-like Receptor in Non-small Cell Lung Cancer.
Thazin N Aung, Niki Gavrielatou, Ioannis A Vathiotis, Aileen I Fernandez, Saba Shafi, Dallas B Flies

Cancer Res Commun· March 2023

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Remodeling the tumor microenvironment via blockade of LAIR-1 and TGF-β signaling enables PD-L1-mediated tumor eradication.
Lucas A Horn, Paul L Chariou, Sofia R Gameiro, Haiyan Qin, Masafumi Iida, Dallas Flies

J Clin Invest· April 2022

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Collagen Fragments Produced in Cancer Mediate T Cell Suppression Through Leukocyte-Associated Immunoglobulin-Like Receptor 1.
Saskia V Vijver, Akashdip Singh, Eline T A M Mommers-Elshof, Jan Meeldijk, Ronald Copeland, Dallas Flies

Front Immunol· December 2021

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Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction.
M Ines Pascoal Ramos, Linjie Tian, Emma J de Ruiter, Chang Song, Ana Paucarmayta, Dallas Flies

Elife· June 2021

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Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes.
Sarah F Adams, Alizée J Grimm, Cheryl L-L Chiang, Ananda Mookerjee, Dallas Flies

J Immunother Cancer· August 2020

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PD-1H (VISTA)-mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus.
Xue Han, Matthew D Vesely, Wendy Yang, Miguel F Sanmamed, Ti Badri, Dallas B Flies

Sci Transl Med· December 2019

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Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy.
Jun Wang, Jingwei Sun, Linda N Liu, Dallas B Flies, Xinxin Nie

Nat Med· April 2019

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Programmed death one homolog maintains the pool size of regulatory T cells by promoting their differentiation and stability.
Qi Wang, Jianwei He, Dallas B Flies, Liqun Luo, Lieping Chen

Sci Rep· July 2017

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Immune checkpoint blockade reveals the stimulatory capacity of tumor-associated CD103(+) dendritic cells in late-stage ovarian cancer.
Dallas B Flies, Tomoe Higuchi, Jaryse C Harris, Vibha Jha, Phyllis A Gimotty

Oncoimmunology· August 2016

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CTLA-4 Blockade Synergizes Therapeutically with PARP Inhibition in BRCA1-Deficient Ovarian Cancer.
Tomoe Higuchi, Dallas B Flies, Nicole A Marjon, Gina Mantia-Smaldone, Lukas Ronner

Cancer Immunol Res· November 2015

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Mechanistic Assessment of PD-1H Coinhibitory Receptor-Induced T Cell Tolerance to Allogeneic Antigens.
Dallas B Flies, Tomoe Higuchi, Lieping Chen

J Immunol· June 2015

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Coinhibitory receptor PD-1H preferentially suppresses CD4⁺ T cell-mediated immunity.
Dallas B Flies, Xue Han, Tomoe Higuchi, Linghua Zheng, Jingwei Sun

J Clin Invest· May 2014

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Strain-specific induction of experimental autoimmune prostatitis (EAP) in mice.
Christopher M Jackson, Dallas B Flies, Claudio A Mosse, Anil Parwani, Edward L Hipkiss

Prostate· May 2013

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Molecular mechanisms of T cell co-stimulation and co-inhibition.
Lieping Chen, Dallas B Flies

Nat Rev Immunol· April 2013

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Blockade of the B7-H1/PD-1 pathway for cancer immunotherapy.
Dallas B Flies, Britt J Sandler, Mario Sznol, Lieping Chen

Yale J Biol Med· December 2011

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