Publications by authors named "Dan Predescu"

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X-inactive-specific transcript: a long noncoding RNA with a complex role in sex differences in human disease.
Dan N Predescu, Babak Mokhlesi, Sanda A Predescu

Biol Sex Differ· December 2024

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Dysregulation of the Long Noncoding RNA X-Inactive-Specific Transcript Expression in Male Patients with Pulmonary Arterial Hypertension.
Brandon L Carman, Shanshan Qin, Dan N Predescu, Malabendu Jana, Rene Cortese, Sanda A Predescu

Am J Pathol· August 2024

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RUNX1 mediates the therapeutic effects of mesenchymal stem cells-derived microparticles in acute respiratory distress syndrome.
Dan Predescu, Shanshan Qin, Vasilios Stefanis, Brandon Carman, Balaji Ganesh, Sanda Predescu

Clin Transl Med· November 2023

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The Impact of Sex Chromosomes in the Sexual Dimorphism of Pulmonary Arterial Hypertension.
Dan N Predescu, Babak Mokhlesi, Sanda A Predescu

Am J Pathol· April 2022

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Up-Regulation of the Long Noncoding RNA X-Inactive-Specific Transcript and the Sex Bias in Pulmonary Arterial Hypertension.
Shanshan Qin, Dan Predescu, Brandon Carman, Priyam Patel, Jiwang Chen, Sanda A Predescu

Am J Pathol· June 2021

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Sex differences in the proliferation of pulmonary artery endothelial cells: implications for plexiform arteriopathy.
Shanshan Qin, Dan N Predescu, Monal Patel, Patrick Drazkowski, Balaji Ganesh, Sanda A Predescu

J Cell Sci· May 2020

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Mesenchymal stem cells-derived extracellular vesicles in acute respiratory distress syndrome: a review of current literature and potential future treatment options.
Trushil G Shah, Dan Predescu, Sanda Predescu

Clin Transl Med· September 2019

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Plexiform Arteriopathy in Rodent Models of Pulmonary Arterial Hypertension.
Brandon L Carman, Dan N Predescu, Roberto Machado, Sanda A Predescu

Am J Pathol· June 2019

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Epsin15 Homology Domains: Role in the Pathogenesis of Pulmonary Arterial Hypertension.
Dan Predescu, Shanshan Qin, Monal Patel, Cristina Bardita, Rabia Bhalli, Sanda Predescu

Front Physiol· October 2018

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Alk5/Runx1 signaling mediated by extracellular vesicles promotes vascular repair in acute respiratory distress syndrome.
Trushil Shah, Shanshan Qin, Mona Vashi, Dan N Predescu, Niranjan Jeganathan, Sanda A Predescu

Clin Transl Med· June 2018

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Pirfenidone reduces subchondral bone loss and fibrosis after murine knee cartilage injury.
Deva D Chan, Jun Li, Wei Luo, Dan N Predescu, Brian J Cole

J Orthop Res· January 2018

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Intersectin-1s deficiency in pulmonary pathogenesis.
Niranjan Jeganathan, Dan Predescu, Sanda Predescu

Respir Res· September 2017

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Modulation of Intersectin-1s Lung Expression Induces Obliterative Remodeling and Severe Plexiform Arteriopathy in the Murine Pulmonary Vascular Bed.
Monal Patel, Dan Predescu, Cristina Bardita, Jiwang Chen, Niranjan Jeganathan, Sanda Predescu

Am J Pathol· March 2017

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Mouse Lung Fibroblast Resistance to Fas-Mediated Apoptosis Is Dependent on the Baculoviral Inhibitor of Apoptosis Protein 4 and the Cellular FLICE-Inhibitory Protein.
Sanda A Predescu, Jian Zhang, Cristina Bardita, Monal Patel, Varun Godbole, Dan N Predescu

Front Physiol· March 2017

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Rac1-mediated cytoskeleton rearrangements induced by intersectin-1s deficiency promotes lung cancer cell proliferation, migration and metastasis.
Niranjan Jeganathan, Dan Predescu, Jin Zhang, Fei Sha, Cristina Bardita, Sanda Predescu

Mol Cancer· September 2016

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Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood-Brain Barrier Integrity and Central Nervous System Homeostasis.
Khiem A Tran, Xianming Zhang, Dan Predescu, Xiaojia Huang, Roberto F Machado

Circulation· January 2016

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New insights into the functions of intersectin-1s.
Sanda Predescu, Cristina Bardita, Dan Predescu

Commun Integr Biol· October 2015

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Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells.
Angelia D Lockett, Daniela N Petrusca, Matthew J Justice, Christophe Poirier, Karina A Serban, Dan Predescu, Sanda Predescu

Am J Physiol Lung Cell Mol Physiol· August 2015

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Endocytic deficiency induced by ITSN-1s knockdown alters the Smad2/3-Erk1/2 signaling balance downstream of Alk5.
Cristina Bardita, Dan N Predescu, Fei Sha, Monal Patel, Ganesh Balaji, Sanda A Predescu

J Cell Sci· April 2015

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Platelet activating factor-induced ceramide micro-domains drive endothelial NOS activation and contribute to barrier dysfunction.
Sanda Predescu, Ivana Knezevic, Cristina Bardita, Radu Florin Neamu, Viktor Brovcovych, Dan Predescu

PLoS One· July 2014

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A novel p38 mitogen-activated protein kinase/Elk-1 transcription factor-dependent molecular mechanism underlying abnormal endothelial cell proliferation in plexogenic pulmonary arterial hypertension.
Monal Patel, Dan Predescu, Rajive Tandon, Cristina Bardita, Jennifer Pogoriler, Sanda Predescu

J Biol Chem· September 2013

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Intersectin-1s: an important regulator of cellular and molecular pathways in lung injury.
Dan N Predescu, Cristina Bardita, Rajive Tandon, Sanda A Predescu

Pulm Circ· September 2013

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Long-term silencing of intersectin-1s in mouse lungs by repeated delivery of a specific siRNA via cationic liposomes. Evaluation of knockdown effects by electron microscopy.
Cristina Bardita, Dan Predescu, Sanda Predescu

J Vis Exp· June 2013

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In vivo knockdown of intersectin-1s alters endothelial cell phenotype and causes microvascular remodeling in the mouse lungs.
Cristina Bardita, Dan Predescu, Matthew J Justice, Irina Petrache, Sanda Predescu

Apoptosis· January 2013

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Impaired caveolae function and upregulation of alternative endocytic pathways induced by experimental modulation of intersectin-1s expression in mouse lung endothelium.
Dan N Predescu, Radu Neamu, Cristina Bardita, Minhua Wang, Sanda A Predescu

Biochem Res Int· August 2012

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