Publications by authors named "Daniel A Lawrence"

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Occludin acts as a dynein adaptor regulating permeability and collateral angiogenesis.
Xuwen Liu, Enming J Su, Alyssa Dreffs, John P Gillies, Madeline Merlino, Daniel A Lawrence

Proc Natl Acad Sci U S A· December 2025

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Immersion-Based Clearing and Autofluorescence Quenching in Myocardial Tissue.
Victoria E Sturgess, Nadia K Korovesis, Domingo E Uceda, Ali Citalan-Madrid, Eric V Vu, Daniel A Lawrence

Microcirculation· November 2025

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Targeting Plasminogen Activator Inhibitor-1 with a Novel Small Molecule Inhibitor Attenuates Lung Fibrosis.
Thomas H Sisson, Sean Fortier, Lam C Tsoi, Roxann Alonzo, Natalya Subbotina, Daniel A Lawrence

Res Sq· August 2025

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Targeting autophagy and plasminogen activator inhibitor-1 increases survival and remodels the tumor microenvironment in glioblastoma.
Sophie G Shifman, Jennifer L O'Connor, Daniel P Radin, Aryan Sharma, Laura Infante, Daniel A Lawrence

J Exp Clin Cancer Res· July 2025

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Micrometer-scale tPA beads amplify plasmin generation for enhanced thrombolytic therapy.
Matthew J Osmond, Fabrice Dabertrand, Nidia Quillinan, Enming J Su, Daniel A Lawrence

Bioeng Transl Med· July 2025

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PAI-1 interaction with sortilin-related receptor 1 is required for lung fibrosis.
Thomas H Sisson, John J Osterholzer, Lisa Leung, Venkatesha Basrur, Alexey Nesvizhskii, Daniel A Lawrence

JCI Insight· June 2025

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Secreted Protease CpaA Inhibits Factor XII-Mediated Bradykinin Generation and Neutrophil Activation.
Kris M Blair, Dillon J Bohinc, Kara L Bane, Mark Warnock, Basel Abuaita, Daniel A Lawrence

Circ Res· June 2025

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Occludin Acts as a Dynein Adaptor Regulating Permeability and Collateral Angiogenesis.
Xuwen Liu, Enming J Su, Alyssa Dreffs, John P Gillies, Madeline Merlino, Daniel A Lawrence

bioRxiv· June 2025

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PA System in the Pathogenesis of Ischemic Stroke.
Boxin Zhang, Lisa Leung, Enming J Su, Daniel A Lawrence

Arterioscler Thromb Vasc Biol· May 2025

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PDGFRα inhibition reduces myofibroblast expansion in the fibrotic rim and enhances recovery after ischemic stroke.
Jil Protzmann, Manuel Zeitelhofer, Christina Stefanitsch, Daniel Torrente, Milena Z Adzemovic, Daniel A Lawrence

J Clin Invest· January 2025

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The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity.
Daniel Torrente, Enming J Su, Alí Francisco Citalán-Madrid, Gerald P Schielke, Daniel Magaoay, Daniel A Lawrence

J Neuroinflammation· January 2025

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Photoacoustic and fluorescence dual-modality imaging of cerebral biomarkers in Alzheimer's disease rodent model.
Tianqu Zhai, Wei Zhang, Chenshuo Ma, Yanhui Ma, Yannis Mantas Paulus, Daniel A Lawrence

J Biomed Opt· December 2024

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Harnessing micrometer-scale tPA beads for high plasmin generation and accelerated fibrinolysis.
Matthew J Osmond, Fabrice Dabertrand, Nidia Quillinan, Enming J Su, Daniel A Lawrence

bioRxiv· November 2024

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Thrombolysis exacerbates cerebrovascular injury after ischemic stroke via a VEGF-B dependent effect on adipose lipolysis.
Ingrid Nilsson, Enming J Su, Linda Fredriksson, Benjamin Heller Sahlgren, Zsuzsa Bagoly, Anna-Lisa E Lawrence, Daniel A Lawrence

bioRxiv· October 2024

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PAI-1 Interaction with Sortilin Related Receptor-1 is Required for Lung Fibrosis.
Thomas H Sisson, John J Osterholzer, Lisa Leung, Venkatesha Basrur, Alexey Nesvizhskii, Daniel A Lawrence

bioRxiv· August 2024

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SORL1 is a receptor for tau that promotes tau seeding.
Joanna M Cooper, Aurelien Lathuiliere, Enming J Su, Yuyu Song, Daniel Torrente, Daniel A Lawrence

J Biol Chem· June 2024

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Magnetically powered microwheel thrombolysis of occlusive thrombi in zebrafish.
M Hao Hao Pontius, Chia-Jui Ku, Matthew J Osmond, Dante Disharoon, Yang Liu, Daniel A Lawrence

Proc Natl Acad Sci U S A· March 2024

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Beta1-receptor blockade attenuates atherosclerosis progression following traumatic brain injury in apolipoprotein E deficient mice.
Jintao Wang, Jessica Venugopal, Paul Silaghi, Enming J Su, Chiao Guo, Daniel A Lawrence

PLoS One· May 2023

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Opposing effects of β-2 and β-1 adrenergic receptor signaling on neuroinflammation and dopaminergic neuron survival in α-synuclein-mediated neurotoxicity.
Daniel Torrente, Enming J Su, Gerald P Schielke, Mark Warnock, Kris Mann, Daniel A Lawrence

J Neuroinflammation· March 2023

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Deep mutational scanning and massively parallel kinetics of plasminogen activator inhibitor-1 functional stability to probe its latency transition.
Laura M Haynes, Zachary M Huttinger, Andrew Yee, Colin A Kretz, David R Siemieniak, Daniel A Lawrence

J Biol Chem· December 2022

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Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin.
Kyle Kihn, Elisa Marchiori, Giovanni Spagnolli, Alberto Boldrini, Luca Terruzzi, Daniel A Lawrence

J Biol Chem· December 2022

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Diabetes and the treatment of ischemic stroke.
Enming J Su, Daniel A Lawrence

J Diabetes Complications· November 2022

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Compartmentalized Actions of the Plasminogen Activator Inhibitors, PAI-1 and Nsp, in Ischemic Stroke.
Daniel Torrente, Enming Joseph Su, Linda Fredriksson, Mark Warnock, David Bushart, Daniel A Lawrence

Transl Stroke Res· October 2022

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Defibrotide Therapy for SARS-CoV-2 ARDS.
David Frame, Gianni B Scappaticci, Thomas M Braun, Mary Maliarik, Thomas H Sisson, Daniel A Lawrence

Chest· August 2022

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Thrombolytic tPA-induced hemorrhagic transformation of ischemic stroke is mediated by PKCβ phosphorylation of occludin.
Andreia Goncalves, Enming J Su, Arivalagan Muthusamy, Manuel Zeitelhofer, Daniel Torrente, Daniel A Lawrence

Blood· July 2022

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