Publications by authors named "Daniel A Rappolee"

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Novel kinetic and developmental transcriptomic pan-stress responses by embryonic stem cells.
Aditi Singh, Ximena Lu Ruden, Wen Tang, Awoniyi Olumide Awonuga, Douglas Mark Ruden, Daniel Allen Rappolee

Sci Rep· July 2025

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Effects of gravity, microgravity or microgravity simulation on early mouse embryogenesis: A review of the first two space embryo studies.
Douglas M Ruden, Daniel A Rappolee

Mechanobiol Med· December 2024

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A Single Cell Transcriptomic Fingerprint of Stressed Premature, Imbalanced Differentiation of Embryonic Stem Cells.
Ximena L Ruden, Aditi Singh, Teya Marben, Wen Tang, Awoniyi O Awonuga, Daniel A Rappolee

Birth Defects Res· November 2024

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Determinants of Embryo Implantation: Roles of the Endometrium and Embryo in Implantation Success.
Awoniyi O Awonuga, Olivia G Camp, Husam M Abu-Soud, Daniel A Rappolee, Elizabeth E Puscheck

Reprod Sci· August 2023

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Epigenetic Reprogramming in and : From Fertilization to Primordial Germ Cell Development.
Aditi Singh, Daniel A Rappolee, Douglas M Ruden

Cells· July 2023

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Pathological epigenetic events and reversibility review: the intersection between hallmarks of aging and developmental origin of health and disease.
Douglas M Ruden, Aditi Singh, Daniel A Rappolee

Epigenomics· July 2023

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Using high throughput screens to predict miscarriages with placental stem cells and long-term stress effects with embryonic stem cells.
Elizabeth E Puscheck, Ximena Ruden, Aditi Singh, Mohammed Abdulhasan, Douglas M Ruden, Daniel A Rappolee

Birth Defects Res· October 2022

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Using Live Imaging and Fluorescence Ubiquitinated Cell Cycle Indicator Embryonic Stem Cells to Distinguish G1 Cell Cycle Delays for General Stressors like Perfluoro-Octanoic Acid and Hyperosmotic Sorbitol or G2 Cell Cycle Delay for Mutagenic Stressors like Benzo(a)pyrene.
Mohammed Abdulhasan, Ximena Ruden, Teya Marben, Sean Harris, Douglas M Ruden, Daniel A Rappolee

Stem Cells Dev· June 2022

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Stress Decreases Host Viral Resistance and Increases Covid Susceptibility in Embryonic Stem Cells.
Mohammed Abdulhasan, Ximena Ruden, Benjamin Rappolee, Sudipta Dutta, Katherine Gurdziel, Daniel A Rappolee

Stem Cell Rev Rep· December 2021

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Using Live Imaging and FUCCI Embryonic Stem Cells to Rank DevTox Risks: Adverse Growth Effects of PFOA Compared With DEP Are 26 Times Faster, 1,000 Times More Sensitive, and 13 Times Greater in Magnitude.
Mohammed Abdulhasan, Ximena Ruden, Yuan You, Sean M Harris, Douglas M Ruden, Daniel A Rappolee

Front Toxicol· November 2021

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Phthalate Exposure and Long-Term Epigenomic Consequences: A Review.
Sudipta Dutta, Diana K Haggerty, Daniel A Rappolee, Douglas M Ruden

Front Genet· May 2020

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Stress Forces First Lineage Differentiation of Mouse Embryonic Stem Cells; Validation of a High-Throughput Screen for Toxicant Stress.
Quanwen Li, Erica Louden, Jordan Zhou, Sascha Drewlo, Jing Dai, Daniel A Rappolee

Stem Cells Dev· January 2019

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Effects of Gravity, Microgravity or Microgravity Simulation on Early Mammalian Development.
Douglas M Ruden, Alan Bolnick, Awoniyi Awonuga, Mohammed Abdulhasan, Gloria Perez, Daniel A Rappolee

Stem Cells Dev· September 2018

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Why AMPK agonists not known to be stressors may surprisingly contribute to miscarriage or hinder IVF/ART.
Elizabeth E Puscheck, Alan Bolnick, Awoniyi Awonuga, Yu Yang, Mohammed Abdulhasan, Daniel A Rappolee

J Assist Reprod Genet· August 2018

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Two-cell embryos are more sensitive than blastocysts to AMPK-dependent suppression of anabolism and stemness by commonly used fertility drugs, a diet supplement, and stress.
Alan Bolnick, Mohammed Abdulhasan, Brian Kilburn, Yufen Xie, Mindie Howard, Daniel A Rappolee

J Assist Reprod Genet· December 2017

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Using stem cell oxygen physiology to optimize blastocyst culture while minimizing hypoxic stress.
Alan Bolnick, Awoniyi O Awonuga, Yu Yang, Mohammed Abdulhasan, Yufen Xie, Daniel A Rappolee

J Assist Reprod Genet· October 2017

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Hypoxic Stress Forces Adaptive and Maladaptive Placental Stress Responses in Early Pregnancy.
Yu Yang, Mohammed Abdulhasan, Awoniyi Awonuga, Alan Bolnick, Elizabeth E Puscheck, Daniel A Rappolee

Birth Defects Res· October 2017

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Departure from optimal O level for mouse trophoblast stem cell proliferation and potency leads to most rapid AMPK activation.
Yu Yang, Zhongliang Jiang, Alan Bolnick, Jing Dai, Elizabeth E Puscheck, Daniel A Rappolee

J Reprod Dev· February 2017

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Hypoxic Stress Forces Irreversible Differentiation of a Majority of Mouse Trophoblast Stem Cells Despite FGF4.
Yu Yang, Marcia Arenas-Hernandez, Nardhy Gomez-Lopez, Jing Dai, Graham C Parker, Daniel A Rappolee

Biol Reprod· November 2016

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Commonly used fertility drugs, a diet supplement, and stress force AMPK-dependent block of stemness and development in cultured mammalian embryos.
Alan Bolnick, Mohammed Abdulhasan, Brian Kilburn, Yufen Xie, Mindie Howard, Daniel A Rappolee

J Assist Reprod Genet· August 2016

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Direct reprogramming to multipotent trophoblast stem cells, and is pluripotency needed for regenerative medicine either?
Yu Yang, Graham C Parker, Elizabeth E Puscheck, Daniel A Rappolee

Stem Cell Investig· August 2016

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Comparison of 2, 5, and 20 % O2 on the development of post-thaw human embryos.
Yu Yang, Yanwen Xu, Chenhui Ding, Rabea Youcef Khoudja, Mingmei Lin, Daniel A Rappolee

J Assist Reprod Genet· July 2016

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Development and Validation of a Rex1-RFP Potency Activity Reporter Assay That Quantifies Stress-Forced Potency Loss in Mouse Embryonic Stem Cells.
Quanwen Li, Nardhy Gomez-Lopez, Sascha Drewlo, Elly Sanchez-Rodriguez, Jing Dai, Daniel A Rappolee

Stem Cells Dev· February 2016

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Molecular biology of the stress response in the early embryo and its stem cells.
Elizabeth E Puscheck, Awoniyi O Awonuga, Yu Yang, Zhongliang Jiang, Daniel A Rappolee

Adv Exp Med Biol· October 2015

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Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency.
Yufen Xie, Sichang Zhou, Zhongliang Jiang, Jing Dai, Elizabeth E Puscheck, Daniel A Rappolee

Stem Cell Res· November 2014

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