Publications by authors named "Daniel Brigham"

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Maximizing ER-α Degradation Maximizes Activity in a Tamoxifen-Resistant Breast Cancer Model: Identification of GDC-0927.
Mehmet Kahraman, Steven P Govek, Johnny Y Nagasawa, Andiliy Lai, Celine Bonnefous, Daniel Brigham

ACS Med Chem Lett· January 2019

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Identification of an Orally Bioavailable Chromene-Based Selective Estrogen Receptor Degrader (SERD) That Demonstrates Robust Activity in a Model of Tamoxifen-Resistant Breast Cancer.
Johnny Nagasawa, Steven Govek, Mehmet Kahraman, Andiliy Lai, Celine Bonnefous, Daniel Brigham

J Med Chem· September 2018

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Discovery and optimization of a highly efficacious class of 5-aryl-2-aminopyridines as FMS-like tyrosine kinase 3 (FLT3) inhibitors.
Gang Liu, Sunny Abraham, Xing Liu, Shimin Xu, Allison M Rooks, Daniel Brigham

Bioorg Med Chem Lett· September 2015

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Identification of GDC-0810 (ARN-810), an Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) that Demonstrates Robust Activity in Tamoxifen-Resistant Breast Cancer Xenografts.
Andiliy Lai, Mehmet Kahraman, Steven Govek, Johnny Nagasawa, Celine Bonnefous, Daniel Brigham

J Med Chem· June 2015

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Discovery of AC710, a Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases.
Gang Liu, Brian T Campbell, Mark W Holladay, Julia M Ford Pulido, Helen Hua, Daniel Brigham

ACS Med Chem Lett· December 2012

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AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML).
Patrick P Zarrinkar, Ruwanthi N Gunawardane, Merryl D Cramer, Michael F Gardner, Daniel Brigham

Blood· October 2009

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In vivo characterization of the psa genes from Streptococcus pneumoniae in multiple models of infection.
Andrea Marra, Stacey Lawson, Jyoti S Asundi, Daniel Brigham, Alexander E Hromockyj

Microbiology (Reading)· May 2002

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Differential fluorescence induction analysis of Streptococcus pneumoniae identifies genes involved in pathogenesis.
Andrea Marra, Jyoti Asundi, Magdalena Bartilson, Stacey Lawson, Flora Fang, Daniel Brigham

Infect Immun· March 2002

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