Publications by authors named "Daniel C Nelson"

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Endolysins: targeting in its major anatomical niches of infection and addressing the hurdles.
Giovanna Castallanos, Norberto Gonzalez-Juarbe, Daniel C Nelson

Front Microbiol· October 2025

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Harnessing mRNA to unleash endolysins: A new frontier in antibacterial therapy.
Daniel C Nelson, Urmil M Dave, Norberto Gonzalez-Juarbe

Mol Ther Nucleic Acids· September 2024

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Engineered antibodies targeted to bacterial surface integrate effector functions with toxin neutralization to provide superior efficacy against bacterial infections.
Rajan P Adhikari, Farhang Alem, Daniel Kemboi, Tulasikumari Kanipakala, Shardulendra P Sherchand, Daniel C Nelson

medRxiv· September 2024

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SP-CHAP, an endolysin with enhanced activity against biofilm pneumococci and nasopharyngeal colonization.
Adit B Alreja, Amanda E Appel, Jinyi C Zhu, Sean P Riley, Norberto Gonzalez-Juarbe, Daniel C Nelson

mBio· April 2024

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Bacteriophage endolysin treatment for systemic infection of Streptococcus iniae in hybrid striped bass.
Michael B Deshotel, Urmil M Dave, Bradley Farmer, Daniel Kemboi, Daniel C Nelson

Fish Shellfish Immunol· February 2024

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Immunogenic epitope scanning in bacteriolytic enzymes Pal and Cpl-1 and engineering Pal to escape antibody responses.
Marek Adam Harhala, Katarzyna Gembara, Izabela Rybicka, Zuzanna Maria Kaźmierczak, Paulina Miernikiewicz, Daniel C Nelson

Front Immunol· October 2023

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A unique borrelial protein facilitates microbial immune evasion.
Shelby D Foor, Kalvis Brangulis, Anil K Shakya, Vipin S Rana, Sandhya Bista, Daniel C Nelson

mBio· October 2023

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Thermal Characterization and Interaction of the Subunits from the Multimeric Bacteriophage Endolysin PlyC.
J Todd Hoopes, Ryan D Heselpoth, Frederick P Schwarz, Daniel C Nelson

Biology (Basel)· September 2023

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Understanding the Molecular Basis for Homodimer Formation of the Pneumococcal Endolysin Cpl-1.
Adit B Alreja, Sara B Linden, Harrison R Lee, Kinlin L Chao, Osnat Herzberg, Daniel C Nelson

ACS Infect Dis· May 2023

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Bacteriophage endolysin powders for inhaled delivery against pulmonary infections.
Yuncheng Wang, Dipesh Khanal, Adit B Alreja, Hang Yang, Rachel Yk Chang, Daniel C Nelson

Int J Pharm· March 2023

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Immunogenicity of Endolysin PlyC.
Marek Adam Harhala, Katarzyna Gembara, Daniel C Nelson, Paulina Miernikiewicz, Krystyna Dąbrowska

Antibiotics (Basel)· July 2022

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Controlled Proteolysis of an Essential Virulence Determinant Dictates Infectivity of Lyme Disease Pathogens.
Meghna Thakur, Sandhya Bista, Shelby D Foor, Shraboni Dutta, Xiuli Yang, Daniel C Nelson

Infect Immun· May 2022

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Structure of Escherichia coli O157:H7 bacteriophage CBA120 tailspike protein 4 baseplate anchor and tailspike assembly domains (TSP4-N).
Kinlin L Chao, Xiaoran Shang, Julia Greenfield, Sara B Linden, Adit B Alreja, Daniel C Nelson

Sci Rep· February 2022

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Computational models in the service of X-ray and cryo-electron microscopy structure determination.
Andriy Kryshtafovych, John Moult, Reinhard Albrecht, Geoffrey A Chang, Kinlin Chao, Daniel C Nelson

Proteins· December 2021

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DNA Dye Sytox Green in Detection of Bacteriolytic Activity: High Speed, Precision and Sensitivity Demonstrated With Endolysins.
Marek Harhala, Katarzyna Gembara, Paulina Miernikiewicz, Barbara Owczarek, Zuzanna Kaźmierczak, Daniel C Nelson

Front Microbiol· October 2021

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High avidity drives the interaction between the streptococcal C1 phage endolysin, PlyC, with the cell surface carbohydrates of Group A Streptococcus.
Sebastian S Broendum, Daniel E Williams, Brooke K Hayes, Felix Kraus, James Fodor, Daniel C Nelson

Mol Microbiol· August 2021

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Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin.
Harley King, Sowmya Ajay Castro, Amol Arunrao Pohane, Cynthia M Scholte, Vincent A Fischetti, Daniel C Nelson

Biochem J· June 2021

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Application of bacteriophage-derived endolysins to combat streptococcal disease: current state and perspectives.
Sara B Linden, Adit B Alreja, Daniel C Nelson

Curr Opin Biotechnol· April 2021

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Structure and function of bacteriophage CBA120 ORF211 (TSP2), the determinant of phage specificity towards E. coli O157:H7.
Julia Greenfield, Xiaoran Shang, Heng Luo, Yan Zhou, Sara B Linden, Daniel C Nelson

Sci Rep· September 2020

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Characterization of the Bacteriophage-Derived Endolysins PlySs2 and PlySs9 with In Vitro Lytic Activity against Bovine Mastitis .
Niels Vander Elst, Sara B Linden, Rob Lavigne, Evelyne Meyer, Yves Briers, Daniel C Nelson

Antibiotics (Basel)· September 2020

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Linker Editing of Pneumococcal Lysin ClyJ Conveys Improved Bactericidal Activity.
Hang Yang, Dehua Luo, Irina Etobayeva, Xiaohong Li, Yujing Gong, Daniel C Nelson

Antimicrob Agents Chemother· January 2020

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Characterization of LysBC17, a Lytic Endopeptidase from .
Steven M Swift, Irina V Etobayeva, Kevin P Reid, Jerel J Waters, Brian B Oakley, Daniel C Nelson

Antibiotics (Basel)· September 2019

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The PlyB Endolysin of Bacteriophage vB_BanS_Bcp1 Exhibits Broad-Spectrum Bactericidal Activity against Isolates.
Raymond Schuch, Adam J Pelzek, Daniel C Nelson, Vincent A Fischetti

Appl Environ Microbiol· May 2019

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Structure and tailspike glycosidase machinery of ORF212 from E. coli O157:H7 phage CBA120 (TSP3).
Julia Greenfield, Xiaoran Shang, Heng Luo, Yan Zhou, Ryan D Heselpoth, Daniel C Nelson

Sci Rep· May 2019

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Contributions of Net Charge on the PlyC Endolysin CHAP Domain.
Xiaoran Shang, Daniel C Nelson

Antibiotics (Basel)· May 2019

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