Publications by authors named "Daniel D Billadeau"

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Genomic and Immune Landscape of Pancreatic Ductal Adenocarcinoma Associated with Germline Pathogenic Variants in ATM.
Siddhartha Yadav, Riyue Bao, Rondell P Graham, Chunling Hu, Steven N Hart, Daniel D Billadeau

Clin Cancer Res· November 2025

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Artificial Clinic Intelligence (ACI): A Generative AI-Powered Modeling Platform to Optimize Patient Cohort Enrichment and Clinical Trial Optimization.
Choong-Yong Ung, Cristina Correia, Zhuofei Zhang, Carter Caya, Shizhen Zhu, Daniel D Billadeau

Cancers (Basel)· November 2025

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Nuclear VAV1 increases GLI1-dependent transcription in pancreatic cancer cells.
Brooke R Tader, Luciana L Almada, Murat Toruner, Kayla C LaRue-Nolan, David L Marks, Daniel D Billadeau

J Biol Chem· November 2025

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A Dual Role for NKG7 in T-cell Cytotoxicity and Longevity.
Haidong Dong, Hyoungjun Ham, Whitney Barham, Ti Wen, Jacob B Hirdler, Daniel D Billadeau

Cancer Immunol Res· October 2025

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An Orally Available Grafted Peptide Targeting Epidermal Growth Factor Receptor Dimers Reduces Non-Small Cell Lung Cancer Tumors in Mouse Models.
Prajesh Shrestha, Sitanshu S Singh, Achyut Dahal, Vivitri Prasasty, Arpan Chowdhury, Daniel D Billadeau

ACS Pharmacol Transl Sci· October 2025

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VPS29C: Adding complexity to the Retromer complex.
Baoyu Chen, Ezra Burstein, Daniel D Billadeau

Proc Natl Acad Sci U S A· August 2025

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A novel dominant-negative variant of IRF8 in a mother and son: Clinical, phenotypic and biological characteristics.
Hyoungjun Ham, Crescent R Isham, Elizabeth H Ristagno, Cristina Correia, Scott M Ennis, Daniel D Billadeau

J Allergy Clin Immunol· June 2025

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CCDC22 mutations that impair COMMD binding cause attenuated 3C/Ritscher-Schinzel syndrome.
Amika Singla, Carolyn Rogers, Mary-Joe Touma, Yassin El-Najjar, Alison Colley, Daniel D Billadeau

BMC Med Genomics· May 2025

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Fatty acid synthase (FASN) inhibition cooperates with BH3 mimetic drugs to overcome resistance to mitochondrial apoptosis in pancreatic cancer.
Travis Vander Steen, Ingrid Espinoza, Cristina Duran, Guillem Casadevall, Eila Serrano-Hervás, Daniel D Billadeau

Neoplasia· April 2025

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β-hydroxybutyrate facilitates mitochondrial-derived vesicle biogenesis and improves mitochondrial functions.
Min Tang, Yingfeng Tu, Yanqiu Gong, Qin Yang, Jinrui Wang, Daniel D Billadeau

Mol Cell· April 2025

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Trans-Golgi network tethering factors regulate TBK1 trafficking and promote the STING-IFN-I pathway.
Jinrui Wang, Shenghui Niu, Xiao Hu, Tianxing Li, Shengduo Liu, Daniel D Billadeau

Cell Discov· March 2025

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Cryo-EM structure of the BLOC-3 complex provides insights into the pathogenesis of Hermansky-Pudlak syndrome.
Xin Yong, Guowen Jia, Qin Yang, Chunzhuang Zhou, Sitao Zhang, Daniel D Billadeau

Nat Commun· March 2025

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Lysosomal NKG7 restrains mTORC1 activity to promote CD8 T cell durability and tumor control.
Hyoungjun Ham, Jacob B Hirdler, Daniel T Bihnam, Zhiming Mao, Joanina K Gicobi, Daniel D Billadeau

Nat Commun· February 2025

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PD-1 prelimits both the cytotoxic and exhaustion potential in thymic CD8+ T cells and impacts the maintenance of peripheral tumor immunity.
Zhiming Mao, Jacob B Hirdler, Joanina K Gicobi, Mark Maynes, Michelle A Hsu, Daniel D Billadeau

bioRxiv· January 2025

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The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O Watzlawik, Daniel D Billadeau

Nat Commun· November 2024

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Structural basis for Retriever-SNX17 assembly and endosomal sorting.
Amika Singla, Daniel J Boesch, Ho Yee Joyce Fung, Chigozie Ngoka, Avery S Enriquez, Daniel D Billadeau

Nat Commun· November 2024

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Loss of HD-PTP function results in lipodystrophy, defective cellular signaling and altered lipid homeostasis.
Destiny F Schultz, Brian A Davies, Johanna A Payne, Cole P Martin, Annabel Y Minard, Daniel D Billadeau

J Cell Sci· September 2024

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Germline mutations in a G protein identify signaling cross-talk in T cells.
Hyoungjun Ham, Huie Jing, Ian T Lamborn, Megan M Kober, Alexey Koval, Daniel D Billadeau

Science· September 2024

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The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins.
Huaqing Deng, Guowen Jia, Ping Li, Yingying Tang, Lin Zhao, Daniel D Billadeau

Cell· August 2024

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Structural organization of the retriever-CCC endosomal recycling complex.
Daniel J Boesch, Amika Singla, Yan Han, Daniel A Kramer, Qi Liu, Daniel D Billadeau

Nat Struct Mol Biol· June 2024

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TRIM25 predominately associates with anti-viral stress granules.
Zehua Shang, Sitao Zhang, Jinrui Wang, Lili Zhou, Xinyue Zhang, Daniel D Billadeau

Nat Commun· May 2024

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MADD regulates natural killer cell degranulation through Rab27a activation.
Michael J Medlyn, Easton Maeder, Claire Bradley, Prasad Phatarpekar, Hyoungjun Ham, Daniel D Billadeau

J Cell Sci· April 2024

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Structural basis for Retriever-SNX17 assembly and endosomal sorting.
Amika Singla, Daniel J Boesch, Ho Yee Joyce Fung, Chigozie Ngoka, Avery S Enriquez, Daniel D Billadeau

bioRxiv· March 2024

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The Rise of Hypothesis-Driven Artificial Intelligence in Oncology.
Zilin Xianyu, Cristina Correia, Choong Yong Ung, Shizhen Zhu, Daniel D Billadeau

Cancers (Basel)· February 2024

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Endosomal trafficking inhibitor EGA can control TLR7-mediated IFNα expression by human plasmacytoid dendritic cells.
Matthew J Wiest, Laurie Baert, Chao Gu, Kevin M Gayler, Hyoungjun Ham, Daniel D Billadeau

Front Immunol· December 2023

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