Publications by authors named "Daniel D Lam"

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RLS-associated MEIS transcription factors control distinct processes in human neural stem cells.
Volker Kittke, Chen Zhao, Daniel D Lam, Philip Harrer, Wojciech Krezel

Sci Rep· November 2024

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A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice.
Chia-Luen Leu, Daniel D Lam, Aaro V Salminen, Benedikt Wefers, Lore Becker

Sleep· May 2024

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Spatial enhancer activation influences inhibitory neuron identity during mouse embryonic development.
Elena Dvoretskova, May C Ho, Volker Kittke, Florian Neuhaus, Ilaria Vitali, Daniel D Lam

Nat Neurosci· May 2024

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Intronic elements associated with insomnia and restless legs syndrome exhibit cell-type-specific epigenetic features contributing to MEIS1 regulation.
Daniel D Lam, Ana Antic Nikolic, Chen Zhao, Nazanin Mirza-Schreiber, Wojciech Krężel

Hum Mol Genet· June 2022

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Collagen VI Regulates Motor Circuit Plasticity and Motor Performance by Cannabinoid Modulation.
Daniel D Lam, Rhîannan H Williams, Ernesto Lujan, Koji Tanabe, Georg Huber

J Neurosci· February 2022

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Investigation of dopaminergic signalling in Meis homeobox 1 (Meis1) deficient mice as an animal model of restless legs syndrome.
Lucile Cathiard, Valerie Fraulob, Daniel D Lam, Miguel Torres, Juliane Winkelmann

J Sleep Res· October 2021

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Decreased sensitivity to the anorectic effects of leptin in mice that lack a Pomc-specific neural enhancer.
Elisa S Na, Daniel D Lam, Eva Yokosawa, Jessica M Adams, David P Olson

PLoS One· March 2021

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Role of MEIS1 in restless legs syndrome: From GWAS to functional studies in mice.
Aaro V Salminen, Daniel D Lam, Juliane Winkelmann

Adv Pharmacol· December 2019

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Recessive variants in ZNF142 cause a complex neurodevelopmental disorder with intellectual disability, speech impairment, seizures, and dystonia.
Kamal Khan, Michael Zech, Angela T Morgan, David J Amor, Matej Skorvanek, Daniel D Lam

Genet Med· November 2019

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Update on KMT2B-Related Dystonia.
Michael Zech, Daniel D Lam, Juliane Winkelmann

Curr Neurol Neurosci Rep· November 2019

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A unique de novo gain-of-function variant in associated with intellectual disability and hyperkinetic movement disorder.
Michael Zech, Daniel D Lam, Sandrina Weber, Riccardo Berutti, Kamila Poláková

Cold Spring Harb Mol Case Stud· December 2018

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An appetite for life: brain regulation of hunger and satiety.
Lora K Heisler, Daniel D Lam

Curr Opin Pharmacol· December 2017

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Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria.
Kavaljit H Chhabra, Jessica M Adams, Brian Fagel, Daniel D Lam, Nathan Qi

Diabetes· March 2016

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Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons.
Luke K Burke, Barbora Doslikova, Giuseppe D'Agostino, Megan Greenwald-Yarnell, Teodora Georgescu, Daniel D Lam

Mol Metab· March 2016

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Recessive mutations in the α3 (VI) collagen gene COL6A3 cause early-onset isolated dystonia.
Michael Zech, Daniel D Lam, Ludmila Francescatto, Barbara Schormair, Aaro V Salminen

Am J Hum Genet· June 2015

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Conditional expression of Pomc in the Lepr-positive subpopulation of POMC neurons is sufficient for normal energy homeostasis and metabolism.
Daniel D Lam, Courtney A Attard, Aaron J Mercer, Martin G Myers, Marcelo Rubinstein

Endocrinology· April 2015

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Partially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional threshold.
Daniel D Lam, Flavio S J de Souza, Sofia Nasif, Miho Yamashita, Rodrigo López-Leal

PLoS Genet· February 2015

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Brain glucose sensors play a significant role in the regulation of pancreatic glucose-stimulated insulin secretion.
Mayowa A Osundiji, Daniel D Lam, Jill Shaw, Chen-Yu Yueh, S Pauliina Markkula

Diabetes· February 2012

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Glucokinase inhibitor glucosamine stimulates feeding and activates hypothalamic neuropeptide Y and orexin neurons.
Ligang Zhou, Chen-Yu Yueh, Daniel D Lam, Jill Shaw, Mayowa Osundiji

Behav Brain Res· September 2011

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Leptin does not directly affect CNS serotonin neurons to influence appetite.
Daniel D Lam, Gina M Leinninger, Gwendolyn W Louis, Alastair S Garfield, Oliver J Marston

Cell Metab· May 2011

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Brain serotonin system in the coordination of food intake and body weight.
Daniel D Lam, Alastair S Garfield, Oliver J Marston, Jill Shaw, Lora K Heisler

Pharmacol Biochem Behav· November 2010

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Nutritional state influences Nociceptin/Orphanin FQ peptide receptor expression in the dorsal raphe nucleus.
Magdalena J Przydzial, Alastair S Garfield, Daniel D Lam, Stephen P Moore, Mark L Evans

Behav Brain Res· January 2010

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Role of central melanocortin pathways in energy homeostasis.
Alastair S Garfield, Daniel D Lam, Oliver J Marston, Magdalena J Przydzial, Lora K Heisler

Trends Endocrinol Metab· July 2009

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Distribution and neurochemical characterization of neurons within the nucleus of the solitary tract responsive to serotonin agonist-induced hypophagia.
Daniel D Lam, Ligang Zhou, Andreas Vegge, Philip Y Xiu, Britt T Christensen

Behav Brain Res· January 2009

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Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism.
K Ganesh Kumar, James L Trevaskis, Daniel D Lam, Gregory M Sutton, Robert A Koza

Cell Metab· December 2008

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