Publications by authors named "Daniel D Long"

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Discovery of Axelopran (TD-1211): A Peripherally Restricted μ-Opioid Receptor Antagonist.
Daniel D Long, Scott R Armstrong, David T Beattie, Christina B Campbell, Timothy J Church

ACS Med Chem Lett· December 2019

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Discovery of N-substituted-endo-3-(8-aza-bicyclo[3.2.1]oct-3-yl)-phenol and -phenyl carboxamide series of μ-opioid receptor antagonists.
Lan Jiang, David T Beattie, John R Jacobsen, Samuel Kintz, Glenmar P Obedencio, Daniel D Long

Bioorg Med Chem Lett· July 2017

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Discovery of TD-8954, a clinical stage 5-HT(4) receptor agonist with gastrointestinal prokinetic properties.
R Murray McKinnell, Scott R Armstrong, David T Beattie, Paul R Fatheree, Daniel D Long

Bioorg Med Chem Lett· July 2013

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The in vivo pharmacodynamics of the novel opioid receptor antagonist, TD-1211, in models of opioid-induced gastrointestinal and CNS activity.
Scott R Armstrong, Christina B Campbell, Carrie L Richardson, Ross G Vickery, Pamela R Tsuruda, Daniel D Long

Naunyn Schmiedebergs Arch Pharmacol· June 2013

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The in vitro pharmacological profile of TD-1211, a neutral opioid receptor antagonist.
Pamela R Tsuruda, Ross G Vickery, Daniel D Long, Scott R Armstrong, David T Beattie

Naunyn Schmiedebergs Arch Pharmacol· June 2013

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A multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma.
Daniel D Long, Bryan Frieman, Sharath S Hegde, Craig M Hill, Lan Jiang

Bioorg Med Chem Lett· February 2013

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Discovery, oral pharmacokinetics and in vivo efficacy of velusetrag, a highly selective 5-HT(4) receptor agonist that has achieved proof-of-concept in patients with chronic idiopathic constipation.
Daniel D Long, Scott R Armstrong, David T Beattie, Seok-Ki Choi, Paul R Fatheree

Bioorg Med Chem Lett· October 2012

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Discovery, oral pharmacokinetics and in vivo efficacy of a highly selective 5-HT4 receptor agonist: clinical compound TD-2749.
Daniel D Long, Scott R Armstrong, David T Beattie, Seok-Ki Choi, Paul R Fatheree

Bioorg Med Chem Lett· July 2012

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A multivalent approach to the design and discovery of orally efficacious 5-HT4 receptor agonists.
R Murray McKinnell, Scott R Armstrong, David T Beattie, Seok-Ki Choi, Paul R Fatheree, Daniel D Long

J Med Chem· September 2009

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Novel heterodimer antibiotics: a review of recent patent literature.
Daniel D Long, Daniel G Marquess

Future Med Chem· September 2009

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A multivalent approach to drug discovery for novel antibiotics.
Daniel D Long, James B Aggen, Burton G Christensen, J Kevin Judice, Sharath S Hegde

J Antibiot (Tokyo)· October 2008

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Exploring the positional attachment of glycopeptide/beta-lactam heterodimers.
Daniel D Long, James B Aggen, Jason Chinn, Seok-Ki Choi, Burton G Christensen

J Antibiot (Tokyo)· October 2008

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Helix-forming carbohydrate amino acids.
Timothy D W Claridge, Daniel D Long, Christopher M Baker, Barbara Odell, Guy H Grant

J Org Chem· March 2005

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