Publications by authors named "Daniel Fil"

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EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma.
Jacob L Edmondson, Megan R Reed, Daniel Fil, Billie Heflin, Alyson McKinnon

iScience· June 2025

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Design and validation of cell-based potency assays for frataxin supplementation treatments.
Shibani Mukherjee, Larisa Pereboeva, Daniel Fil, Achisha Saikia, Jeon Lee

Mol Ther Methods Clin Dev· December 2024

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Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma.
Lauren C Morehead, Brian Koss, Daniel Fil, Billie Heflin, Sarita Garg

Mol Immunol· November 2023

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Chemical inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 helper and CD8 effector T cells.
Ana C Azevedo-Pouly, Lauren E Appell, Lyle Burdine, Lora J Rogers, Lauren C Morehead, Daniel Fil

Immunol Cell Biol· August 2023

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in the enteric nervous system is preferentially expressed during early postnatal development in mouse as DM20, whose expression appears reliant on an intronic enhancer.
Pankaj Patyal, Daniel Fil, Patricia A Wight

Front Cell Neurosci· May 2023

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Neurobehavioral deficits of mice expressing a low level of G127V mutant frataxin.
Daniel Fil, Robbie L Conley, Aamir R Zuberi, Cathleen M Lutz, Terry Gemelli

Neurobiol Dis· February 2023

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transgenic mice reveal that splice variants containing "human-specific" exons are relatively minor in comparison to the archetypal transcript and that an upstream regulatory element bolsters expression during early postnatal brain development.
Pankaj Patyal, Daniel Fil, Hamdan Hamdan, Patricia A Wight

Front Cell Neurosci· January 2023

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Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models.
Alicja Urbaniak, Megan R Reed, Daniel Fil, Anika Moorjani, Sarah Heflin

Biomed Pharmacother· September 2021

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Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia.
Daniel Fil, Balu K Chacko, Robbie Conley, Xiaosen Ouyang, Jianhua Zhang

Dis Model Mech· July 2020

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Excision of the expanded GAA repeats corrects cardiomyopathy phenotypes of iPSC-derived Friedreich's ataxia cardiomyocytes.
Jixue Li, Natalia Rozwadowska, Amanda Clark, Daniel Fil, Jill S Napierala

Stem Cell Res· October 2019

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RNA-Seq Analysis of Spinal Cord Tissues from hPFN1 Transgenic Mouse Model of ALS at Pre-symptomatic and End-Stages of Disease.
Caroline Barham, Daniel Fil, Stephanie D Byrum, Yasir Rahmatallah, Galina Glazko

Sci Rep· September 2018

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Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy.
Rebecca J Holley, Stuart M Ellison, Daniel Fil, Claire O'Leary, John McDermott

Brain· January 2018

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Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.
Daniel Fil, Abigail DeLoach, Shilpi Yadav, Duah Alkam, Melanie MacNicol

Hum Mol Genet· February 2017

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Functional and RNA expression profile of adenosine receptor subtypes in mouse mesenteric arteries.
Bunyen Teng, Daniel Fil, Stephen L Tilley, Catherine Ledent, Thomas Krahn

J Cardiovasc Pharmacol· January 2013

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NADPH oxidase pathway is involved in aortic contraction induced by A3 adenosine receptor in mice.
Mohammed S El-Awady, Habib R Ansari, Daniel Fil, Stephen L Tilley, S Jamal Mustafa

J Pharmacol Exp Ther· August 2011

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A broad upregulation of cerebral chemokine genes by peripherally-generated inflammatory mediators.
Daniel Fil, Elizabeth Borysiewicz, Gregory W Konat

Metab Brain Dis· March 2011

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Peripheral immune challenge with dsRNA enhances kainic acid-induced status epilepticus.
Lindsay T Kirschman, Elizabeth Borysiewicz, Daniel Fil, Gregory W Konat

Metab Brain Dis· March 2011

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Phosphodiesterase 4B2 gene is an effector of Toll-like receptor signaling in astrocytes.
Elizabeth Borysiewicz, Daniel Fil, Daniel Dlaboga, James M O'Donnell, Gregory W Konat

Metab Brain Dis· September 2009

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Rho proteins are negative regulators of TLR2, TLR3, and TLR4 signaling in astrocytes.
Elizabeth Borysiewicz, Daniel Fil, Gregory W Konat

J Neurosci Res· May 2009

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Peripheral challenge with double-stranded RNA elicits global up-regulation of cytokine gene expression in the brain.
Gregory W Konat, Elizabeth Borysiewicz, Daniel Fil, Isaac James

J Neurosci Res· May 2009

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