Publications by authors named "Daniel Gaddy"

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Companion Diagnostic Cu-Liposome Positron Emission Tomography Enables Characterization of Drug Delivery to Tumors and Predicts Response to Cancer Nanomedicines.
Helen Lee, Daniel Gaddy, Manuela Ventura, Nicholas Bernards, Raquel de Souza

Theranostics· April 2019

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Extended topoisomerase 1 inhibition through liposomal irinotecan results in improved efficacy over topotecan and irinotecan in models of small-cell lung cancer.
Shannon C Leonard, Helen Lee, Daniel F Gaddy, Stephan G Klinz, Nancy Paz

Anticancer Drugs· November 2017

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Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response in Patients with Metastatic Breast Cancer.
Helen Lee, Anthony F Shields, Barry A Siegel, Kathy D Miller, Ian Krop, Daniel F Gaddy

Clin Cancer Res· August 2017

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Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302).
Elena Geretti, Shannon Curtis Leonard, Nancy Dumont, Helen Lee, Jinzi Zheng, Daniel F Gaddy

Mol Cancer Ther· September 2015

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Whole-body organ-level and kidney micro-dosimetric evaluations of (64)Cu-loaded HER2/ErbB2-targeted liposomal doxorubicin ((64)Cu-MM-302) in rodents and primates.
Daniel F Gaddy, Helen Lee, Jinzi Zheng, David A Jaffray, Thomas J Wickham

EJNMMI Res· April 2015

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A gradient-loadable (64)Cu-chelator for quantifying tumor deposition kinetics of nanoliposomal therapeutics by positron emission tomography.
Helen Lee, Jinzi Zheng, Daniel Gaddy, Kelly D Orcutt, Shannon Leonard

Nanomedicine· January 2015

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Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death.
Jeremy S Tilstra, Daniel F Gaddy, Jing Zhao, Shaival H Davé, Laura J Niedernhofer

Sci Rep· January 2014

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Impact of tumor HER2/ERBB2 expression level on HER2-targeted liposomal doxorubicin-mediated drug delivery: multiple low-affinity interactions lead to a threshold effect.
Bart S Hendriks, Stephan G Klinz, Joseph G Reynolds, Christopher W Espelin, Daniel F Gaddy

Mol Cancer Ther· September 2013

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In vivo expression of HGF/NK1 and GLP-1 From dsAAV vectors enhances pancreatic ß-cell proliferation and improves pathology in the db/db mouse model of diabetes.
Daniel F Gaddy, Michael J Riedel, Sharmila Pejawar-Gaddy, Timothy J Kieffer, Paul D Robbins

Diabetes· December 2010

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Generation of a tumor vaccine candidate based on conjugation of a MUC1 peptide to polyionic papillomavirus virus-like particles.
Sharmila Pejawar-Gaddy, Yogendra Rajawat, Zoe Hilioti, Jia Xue, Daniel F Gaddy

Cancer Immunol Immunother· November 2010

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Current status of gene therapy for rheumatoid arthritis.
Daniel F Gaddy, Paul D Robbins

Curr Rheumatol Rep· October 2008

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Oncolytic vesicular stomatitis virus induces apoptosis via signaling through PKR, Fas, and Daxx.
Daniel F Gaddy, Douglas S Lyles

J Virol· March 2007

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Vesicular stomatitis viruses expressing wild-type or mutant M proteins activate apoptosis through distinct pathways.
Daniel F Gaddy, Douglas S Lyles

J Virol· April 2005

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