Publications by authors named "Daniel Gamu"

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Using long-read sequencing to detect and subtype a case with Temple syndrome.
Sarah Dada, Vahid Akbari, Duha Hejla, Yaoqing Shen, Katherine Dixon, Daniel Gamu

J Med Genet· July 2025

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NPAS4 Depletion in POMC Neurons Protects From Obesity and Alters the Feeding-regulated Transcriptome in Male Mice.
Ji Soo Yoon, Daniel Gamu, William T Gibson, Francis C Lynn

Endocrinology· May 2025

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Minimally Humanized Exon-18 Mouse Cell Lines Validate Preclinical CRISPR/Cas9 Approach to Treat Weaver Syndrome.
William T Gibson, Tess C Lengyell, Andrea J Korecki, Sanne M Janssen, Bethany A Adair, Daniel Gamu

Hum Gene Ther· March 2025

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Maintenance of thermogenic adipose tissues despite loss of the H3K27 acetyltransferases p300 or CBP.
Daniel Gamu, Makenna S Cameron, William T Gibson

Am J Physiol Endocrinol Metab· October 2024

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Activation of β-catenin in mesenchymal progenitors leads to muscle mass loss.
Nasim Kajabadi, Marcela Low, Erik Jacques, Heta Lad, Lin Wei Tung, Daniel Gamu

Dev Cell· March 2023

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Activating thermogenesis to combat obesity: hot topic or cold front?
Moses Jeong, Daniel Gamu

J Physiol· February 2022

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Searching for Monogenic Diabetes in a High-risk Autoimmune Diabetes Cohort: Needles in a Paperclip Stack.
Daniel Gamu, William T Gibson

J Clin Endocrinol Metab· July 2021

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Phospholamban and sarcolipin prevent thermal inactivation of sarco(endo)plasmic reticulum Ca2+-ATPases.
Minghua Fu, Eric Bombardier, Daniel Gamu, A Russell Tupling

Biochem J· November 2020

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Reciprocal skeletal phenotypes of PRC2-related overgrowth and Rubinstein-Taybi syndromes: potential role of H3K27 modifications.
Daniel Gamu, William T Gibson

Cold Spring Harb Mol Case Stud· August 2020

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The sarcoplasmic reticulum and SERCA: a nexus for muscular adaptive thermogenesis.
Daniel Gamu, Emma Sara Juracic, Karlee J Hall, A Russell Tupling

Appl Physiol Nutr Metab· January 2020

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Phospholamban deficiency does not alter skeletal muscle SERCA pumping efficiency or predispose mice to diet-induced obesity.
Daniel Gamu, Emma Sara Juracic, Val A Fajardo, Bradley Alexander Rietze, Khanh Tran

Am J Physiol Endocrinol Metab· March 2019

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Sarcolipin deletion in mdx mice impairs calcineurin signalling and worsens dystrophic pathology.
Val A Fajardo, Paige J Chambers, Emma S Juracic, Bradley A Rietze, Daniel Gamu

Hum Mol Genet· December 2018

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Genetic deletion of muscle RANK or selective inhibition of RANKL is not as effective as full-length OPG-fc in mitigating muscular dystrophy.
Sébastien S Dufresne, Antoine Boulanger-Piette, Sabrina Bossé, Anteneh Argaw, Dounia Hamoudi, Daniel Gamu

Acta Neuropathol Commun· April 2018

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Fattening the role of Ca cycling in adaptive thermogenesis.
Daniel Gamu, A Russell Tupling

Nat Med· December 2017

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Beetroot Juice Increases Human Muscle Force without Changing Ca2+-Handling Proteins.
Jamie Whitfield, Daniel Gamu, George J F Heigenhauser, Luc J C VAN Loon, Lawrence L Spriet

Med Sci Sports Exerc· October 2017

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Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice.
Val A Fajardo, Daniel Gamu, Andrew Mitchell, Darin Bloemberg, Eric Bombardier

PLoS One· September 2017

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Sarcolipin expression is not required for the mitochondrial enzymatic response to physical activity or diet.
Daniel Gamu, Anton Trinh, Val A Fajardo, Eric Bombardier, A Russell Tupling

J Appl Physiol (1985)· May 2017

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Sarcolipin knockout mice fed a high-fat diet exhibit altered indices of adipose tissue inflammation and remodeling.
Rebecca E K MacPherson, Daniel Gamu, Scott Frendo-Cumbo, Laura Castellani, Frenk Kwon

Obesity (Silver Spring)· July 2016

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Muscle RANK is a key regulator of Ca2+ storage, SERCA activity, and function of fast-twitch skeletal muscles.
Sébastien S Dufresne, Nicolas A Dumont, Antoine Boulanger-Piette, Val A Fajardo, Daniel Gamu

Am J Physiol Cell Physiol· April 2016

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Persistence of diet-induced obesity despite access to voluntary activity in mice lacking sarcolipin.
Daniel Gamu, Anton Trinh, Eric Bombardier, A Russell Tupling

Physiol Rep· September 2015

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Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype.
Val A Fajardo, Eric Bombardier, Elliott McMillan, Khanh Tran, Brennan J Wadsworth, Daniel Gamu

Dis Model Mech· August 2015

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Functional, morphological, and apoptotic alterations in skeletal muscle of ARC deficient mice.
Andrew S Mitchell, Ian C Smith, Daniel Gamu, Stefan Donath, A Russell Tupling

Apoptosis· March 2015

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Co-expression of SERCA isoforms, phospholamban and sarcolipin in human skeletal muscle fibers.
Val A Fajardo, Eric Bombardier, Chris Vigna, Tahira Devji, Darin Bloemberg, Daniel Gamu

PLoS One· September 2014

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Sarcolipin provides a novel muscle-based mechanism for adaptive thermogenesis.
Daniel Gamu, Eric Bombardier, Ian C Smith, Val A Fajardo, A Russell Tupling

Exerc Sport Sci Rev· July 2014

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Sarcolipin trumps β-adrenergic receptor signaling as the favored mechanism for muscle-based diet-induced thermogenesis.
Eric Bombardier, Ian C Smith, Daniel Gamu, Val A Fajardo, Chris Vigna

FASEB J· September 2013

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