Publications by authors named "Daniel Hebert"

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N-glycan-dependent protein maturation and quality control in the ER.
Kevin P Guay, Wen-Chuan Chou, Nathan P Canniff, Kylie B Paul, Daniel N Hebert

Nat Rev Mol Cell Biol· December 2025

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The cysteine-rich domain of SEP15, a selenoprotein co-chaperone of the ER chaperone, UDP-glucose:glycoprotein glucosyltransferase, adopts a novel fold.
Robert V Williams, Kevin P Guay, Owen Hurlbut Lesk, Daniel N Hebert, Lila M Gierasch

bioRxiv· August 2025

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Bi-allelic UGGT1 variants cause a congenital disorder of glycosylation.
Zain Dardas, Laura Harrold, Daniel G Calame, Claire G Salter, Takashi Kikuma, Daniel N Hebert

Am J Hum Genet· May 2025

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Insights into the interaction between UGGT, the gatekeeper of folding in the ER, and its partner, the selenoprotein SEP15.
Robert V Williams, Kevin P Guay, Owen A Hurlbut Lesk, Eugenia M Clerico, Daniel N Hebert

Proc Natl Acad Sci U S A· August 2024

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Rescue of secretion of rare-disease-associated misfolded mutant glycoproteins in UGGT1 knock-out mammalian cells.
Gabor Tax, Kevin P Guay, Ludovica Pantalone, Martina Ceci, Tatiana Soldà, Daniel N Hebert

Traffic· January 2024

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TTC17 is an endoplasmic reticulum resident TPR-containing adaptor protein.
Nathan P Canniff, Jill B Graham, Kevin P Guay, Daniel A Lubicki, Stephen J Eyles, Daniel N Hebert

J Biol Chem· December 2023

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ER chaperones use a protein folding and quality control glyco-code.
Kevin P Guay, Haiping Ke, Nathan P Canniff, Gracie T George, Stephen J Eyles, Daniel N Hebert

Mol Cell· December 2023

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Monitoring the Secretion and Activity of Alpha-1 Antitrypsin in Various Mammalian Cell Types.
Kevin P Guay, Haiping Ke, Lila M Gierasch, Anne Gershenson, Daniel N Hebert

Methods Mol Biol· December 2023

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A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
Kevin P Guay, Roberta Ibba, J L Kiappes, Snežana Vasiljević, Francesco Bonì, Daniel N Hebert

iScience· October 2023

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Rescue of secretion of a rare-disease associated mis-folded mutant glycoprotein in knock-out mammalian cells.
Gábor Tax, Kevin P Guay, Tatiana Soldà, Charlie J Hitchman, Johan C Hill, Daniel N Hebert

bioRxiv· May 2023

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The conformational landscape of a serpin N-terminal subdomain facilitates folding and in-cell quality control.
Upneet Kaur, Kyle C Kihn, Haiping Ke, Weiwei Kuo, Lila M Gierasch, Daniel N Hebert

bioRxiv· April 2023

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Calnexin reveals a sugar-free taste within the lipid bilayer.
Kevin P Guay, Robert V Williams, Daniel N Hebert

EMBO J· December 2022

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Secretion of functional α1-antitrypsin is cell type dependent: Implications for intramuscular delivery for gene therapy.
Haiping Ke, Kevin P Guay, Terence R Flotte, Lila M Gierasch, Anne Gershenson, Daniel N Hebert

Proc Natl Acad Sci U S A· August 2022

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The Role of Endoplasmic Reticulum Chaperones in Protein Folding and Quality Control.
Benjamin M Adams, Nathan P Canniff, Kevin P Guay, Daniel N Hebert

Prog Mol Subcell Biol· August 2021

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Age groups that sustain resurging COVID-19 epidemics in the United States.
Mélodie Monod, Alexandra Blenkinsop, Xiaoyue Xi, Daniel Hebert, Sivan Bershan

Science· March 2021

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Quantitative glycoproteomics reveals cellular substrate selectivity of the ER protein quality control sensors UGGT1 and UGGT2.
Benjamin M Adams, Nathan P Canniff, Kevin P Guay, Ida Signe Bohse Larsen, Daniel N Hebert

Elife· December 2020

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In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin.
Robert Daniels, Daniel N Hebert

mSphere· March 2020

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Endoplasmic reticulum transmembrane protein TMTC3 contributes to O-mannosylation of E-cadherin, cellular adherence, and embryonic gastrulation.
Jill B Graham, Johan C Sunryd, Ketan Mathavan, Emma Weir, Ida Signe Bohse Larsen, Daniel N Hebert

Mol Biol Cell· February 2020

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Proper secretion of the serpin antithrombin relies strictly on thiol-dependent quality control.
Benjamin M Adams, Haiping Ke, Lila M Gierasch, Anne Gershenson, Daniel N Hebert

J Biol Chem· December 2019

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Protein Quality Control in the Endoplasmic Reticulum.
Benjamin M Adams, Michela E Oster, Daniel N Hebert

Protein J· June 2019

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TPR-containing proteins control protein organization and homeostasis for the endoplasmic reticulum.
Jill B Graham, Nathan P Canniff, Daniel N Hebert

Crit Rev Biochem Mol Biol· April 2019

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EDEM1's mannosidase-like domain binds ERAD client proteins in a redox-sensitive manner and possesses catalytic activity.
Lydia Lamriben, Michela E Oster, Taku Tamura, Weihua Tian, Zhang Yang, Daniel N Hebert

J Biol Chem· September 2018

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Expression and Purification of Active Recombinant Human Alpha-1 Antitrypsin (AAT) from Escherichia coli.
Beena Krishnan, Lizbeth Hedstrom, Daniel N Hebert, Lila M Gierasch, Anne Gershenson

Methods Mol Biol· April 2018

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Activating and Repressing IRE1α: The Hsp47 and BiP Tug of War.
Lydia Lamriben, Daniel N Hebert

Mol Cell· January 2018

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Analysis of Disulfide Bond Formation.
Ineke Braakman, Lydia Lamriben, Guus van Zadelhoff, Daniel N Hebert

Curr Protoc Protein Sci· November 2017

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