Publications by authors named "Daniel Maneval"

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Computed tomography sequence integration for enhanced proton therapy in patients with metallic implants.
Daniel Maneval, Luka McNeill, Ronan Penard, Julien Feuillade, Régis Amblard

Phys Med Biol· December 2025

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The safety of recombinant human hyaluronidase PH20 in nonclinical models: An overview of toxicology, pharmacology, and impact of anti-PH20 antibodies.
Ryan P Nolan, David W Kang, Daniel C Maneval, Stephen P Knowles, Michael J LaBarre

J Control Release· October 2024

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JNTX-101, a novel albumin-encapsulated gemcitabine prodrug, is efficacious and operates via caveolin-1-mediated endocytosis.
Tiantian Cui, Sergio Corrales-Guerrero, Veronica Castro-Aceituno, Sindhu Nair, Daniel C Maneval

Mol Ther Oncolytics· September 2023

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A high sensitivity Cherenkov detector for prompt gamma timing and time imaging.
Maxime Jacquet, Saba Ansari, Marie-Laure Gallin-Martel, Adélie André, Yannick Boursier, Daniel Maneval

Sci Rep· March 2023

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Dual Stromal Targeting Sensitizes Pancreatic Adenocarcinoma for Anti-Programmed Cell Death Protein 1 Therapy.
Alex B Blair, Jianxin Wang, John Davelaar, Andrew Baker, Keyu Li, Daniel C Maneval

Gastroenterology· November 2022

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Risk Factors, Hyaluronidase Expression, and Clinical Immunogenicity of Recombinant Human Hyaluronidase PH20, an Enzyme Enabling Subcutaneous Drug Administration.
Marie A Printz, Barry J Sugarman, Rudolph D Paladini, Michael C Jorge, Yan Wang, Daniel C Maneval

AAPS J· October 2022

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Postsurgical geometrical variations of tumor bed and brainstem during photon and proton therapy for pediatric tumors of the posterior fossa: dosimetric impact and predictive factors.
Stefania Volpe, Pierre-Yves Bondiau, Line Claude, Audrey Claren, Laetitia Padovani, Daniel Maneval

Strahlenther Onkol· December 2021

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Safety and pharmacokinetics of docetaxel in combination with pegvorhyaluronidase alfa in patients with non-small cell lung cancer.
Thomas Heineman, Megan Baumgart, Charvi Nanavati, Nash Gabrail, Scott A Van Wart, Daniel C Maneval

Clin Transl Sci· September 2021

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A time-of-flight-based reconstruction for real-time prompt-gamma imaging in proton therapy.
Maxime Jacquet, Sara Marcatili, Marie-Laure Gallin-Martel, Jean-Luc Bouly, Yannick Boursier

Phys Med Biol· June 2021

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A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells.
Drake M Mellott, Chien-Te Tseng, Aleksandra Drelich, Pavla Fajtová, Bala C Chenna, Daniel Maneval

ACS Chem Biol· April 2021

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A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells.
Drake M Mellott, Chien-Te Tseng, Aleksandra Drelich, Pavla Fajtová, Bala C Chenna, Daniel Maneval

bioRxiv· October 2020

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A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Hyaluronidase PH20 Administered Intravenously in Healthy Volunteers.
Marie A Printz, Samuel S Dychter, Emanuel P DeNoia, Rena Harrigan, Barry J Sugarman, Daniel C Maneval

Curr Ther Res Clin Exp· August 2020

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ENHANZE drug delivery technology: a novel approach to subcutaneous administration using recombinant human hyaluronidase PH20.
Kenneth W Locke, Daniel C Maneval, Michael J LaBarre

Drug Deliv· December 2019

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The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44.
Chunmei Zhao, Benjamin J Thompson, Kelly Chen, Feng Gao, Barbara Blouw, Daniel C Maneval

Oncotarget· November 2019

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pGPUMCD: an efficient GPU-based Monte Carlo code for accurate proton dose calculations.
Daniel Maneval, Benoît Ozell, Philippe Després

Phys Med Biol· April 2019

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Long term efficacy and toxicity after stereotactic ablative reirradiation in locally relapsed stage III non-small cell lung cancer.
Shakeel Sumodhee, Pierre-Yves Bondiau, Michel Poudenx, Charlotte Cohen, Arash O Naghavi, Daniel Maneval

BMC Cancer· April 2019

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Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression.
Xiaoming Li, H Michael Shepard, Jessica A Cowell, Chunmei Zhao, Ryan J Osgood, Daniel C Maneval

Clin Cancer Res· October 2018

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Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.
Jeffrey R Infante, Ronald L Korn, Lee S Rosen, Patricia LoRusso, Samuel S Dychter, Daniel C Maneval

Br J Cancer· January 2018

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Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.
Jeffrey R Infante, Ronald L Korn, Lee S Rosen, Patricia LoRusso, Samuel S Dychter, Daniel C Maneval

Br J Cancer· January 2018

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Efficiency improvement in proton dose calculations with an equivalent restricted stopping power formalism.
Daniel Maneval, Hugo Bouchard, Benoît Ozell, Philippe Després

Phys Med Biol· December 2017

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PH20 is not expressed in murine CNS and oligodendrocyte precursor cells.
Mathieu Marella, Joe Ouyang, Jonathan Zombeck, Chunmei Zhao, Lei Huang, Daniel C Maneval

Ann Clin Transl Neurol· March 2017

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Tolerability and pharmacokinetic properties of ondansetron administered subcutaneously with recombinant human hyaluronidase in minipigs and healthy volunteers.
Samuel S Dychter, Rena Harrigan, Jesse D Bahn, Marie A Printz, Barry J Sugarman, Daniel C Maneval

Clin Ther· February 2014

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Phase I trial of intravesical recombinant adenovirus mediated interferon-α2b formulated in Syn3 for Bacillus Calmette-Guérin failures in nonmuscle invasive bladder cancer.
Colin P N Dinney, Mark B Fisher, Neema Navai, Michael A O'Donnell, David Cutler, Daniel C Maneval

J Urol· September 2013

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Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.
Michael A Jacobetz, Derek S Chan, Albrecht Neesse, Tashinga E Bapiro, Natalie Cook, Daniel C Maneval

Gut· January 2013

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Sustained intravesical interferon protein exposure is achieved using an adenoviral-mediated gene delivery system: a study in rats evaluating dosing regimens.
Robert J Connor, Jennifer M Anderson, Todd Machemer, Daniel C Maneval, Heidrun Engler

Urology· July 2005

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