Publications by authors named "Daniel N Grba"

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Global conformations of complex I are distinguished by the binding of a unique interdomain bridging subunit.
Chris Seunggyu Lee, Daniel N Grba, John J Wright, Bozhidar S Ivanov, Judy Hirst

Sci Adv· October 2025

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Biallelic variants cause a progressive neurodevelopmental disorder with prominent dystonia and mitochondrial complex I deficiency.
Francesca Magrinelli, Lucie S Taylor, Sahar Sedighzadeh, Dalila Moualek, Mariasavina Severino, Daniel N Grba

Brain Commun· October 2025

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Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I.
Daniel N Grba, John J Wright, Zhan Yin, William Fisher, Judy Hirst

Science· June 2024

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Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I.
Daniel N Grba, Injae Chung, Hannah R Bridges, Ahmed-Noor A Agip, Judy Hirst

Sci Adv· August 2023

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Insights into a viral motor: the structure of the HK97 packaging termination assembly.
Dorothy E D P Hawkins, Oliver W Bayfield, Herman K H Fung, Daniel N Grba, Alexis Huet

Nucleic Acids Res· July 2023

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Making the leap from structure to mechanism: are the open states of mammalian complex I identified by cryoEM resting states or catalytic intermediates?
Injae Chung, Daniel N Grba, John J Wright, Judy Hirst

Curr Opin Struct Biol· December 2022

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Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I.
Daniel N Grba, James N Blaza, Hannah R Bridges, Ahmed-Noor A Agip, Zhan Yin

J Biol Chem· March 2022

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A conserved arginine residue is critical for stabilizing the N2 FeS cluster in mitochondrial complex I.
Mikhail A Hameedi, Daniel N Grba, Katherine H Richardson, Andrew J Y Jones, Wei Song

J Biol Chem· August 2021

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Structural basis for a complex I mutation that blocks pathological ROS production.
Zhan Yin, Nils Burger, Duvaraka Kula-Alwar, Dunja Aksentijević, Hannah R Bridges, Daniel N Grba

Nat Commun· January 2021

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Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation.
Daniel N Grba, Judy Hirst

Nat Struct Mol Biol· October 2020

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