Publications by authors named "Daniel Obrecht"

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Reply to: Antibiotics and hexagonal order in the bacterial outer membrane.
Selen Manioglu, Seyed Majed Modaresi, Johannes Thoma, Sarah A Overall, Gregory Upert, Daniel Obrecht

Nat Commun· August 2023

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Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae.
Matthias Schuster, Emile Brabet, Kathryn K Oi, Nicolas Desjonquères, Kerstin Moehle, Daniel Obrecht

Sci Adv· May 2023

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Antibiotic polymyxin arranges lipopolysaccharide into crystalline structures to solidify the bacterial membrane.
Selen Manioglu, Seyed Majed Modaresi, Noah Ritzmann, Johannes Thoma, Sarah A Overall, Daniel Obrecht

Nat Commun· October 2022

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Anti-biofilm activity of murepavadin against cystic fibrosis Pseudomonas aeruginosa isolates.
María Díez-Aguilar, Miquel Ekkelenkamp, María-Isabel Morosini, Natalia Huertas, Rosa Del Campo, Daniel Obrecht

J Antimicrob Chemother· September 2021

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Macrocycle Therapeutics to Treat Life-threatening Diseases.
Gokhan Batur, Philipp Ermert, Johann Zimmermann, Daniel Obrecht

Chimia (Aarau)· June 2021

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Murepavadin antimicrobial activity against and resistance development in cystic fibrosis Pseudomonas aeruginosa isolates.
María Díez-Aguilar, Marta Hernández-García, María-Isabel Morosini, Ad Fluit, Michael M Tunney, Daniel Obrecht

J Antimicrob Chemother· March 2021

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Emerging peptide antibiotics with therapeutic potential.
Gregory Upert, Anatol Luther, Daniel Obrecht, Philipp Ermert

Med Drug Discov· March 2021

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Identification of Genes Required for Resistance to Peptidomimetic Antibiotics by Transposon Sequencing.
Alessandra Vitale, Gabriella Pessi, Matthias Urfer, Hans H Locher, Katja Zerbe, Daniel Obrecht

Front Microbiol· July 2020

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Frontier Between Cyclic Peptides and Macrocycles.
Philipp Ermert, Anatol Luther, Peter Zbinden, Daniel Obrecht

Methods Mol Biol· March 2020

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Chimeric peptidomimetic antibiotics against Gram-negative bacteria.
Anatol Luther, Matthias Urfer, Michael Zahn, Maik Müller, Shuang-Yan Wang, Daniel Obrecht

Nature· December 2019

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Author Correction: Chimeric peptidomimetic antibiotics against Gram-negative bacteria.
Anatol Luther, Matthias Urfer, Michael Zahn, Maik Müller, Shuang-Yan Wang, Daniel Obrecht

Nature· December 2019

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Advances in macrocyclic peptide-based antibiotics.
Anatol Luther, Christian Bisang, Daniel Obrecht

Bioorg Med Chem· June 2018

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Protein epitope mimetic macrocycles as biopharmaceuticals.
Anatol Luther, Kerstin Moehle, Eric Chevalier, Glenn Dale, Daniel Obrecht

Curr Opin Chem Biol· June 2017

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Efficacy of the Novel Antibiotic POL7001 in Preclinical Models of Pseudomonas aeruginosa Pneumonia.
Cristina Cigana, Francesca Bernardini, Marcella Facchini, Beatriz Alcalá-Franco, Camilla Riva, Daniel Obrecht

Antimicrob Agents Chemother· August 2016

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Structural studies of β-hairpin peptidomimetic antibiotics that target LptD in Pseudomonas sp.
Jasmin Schmidt, Krystyna Patora-Komisarska, Kerstin Moehle, Daniel Obrecht, John A Robinson

Bioorg Med Chem· September 2013

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Inhibition of lipopolysaccharide transport to the outer membrane in Pseudomonas aeruginosa by peptidomimetic antibiotics.
Martina Werneburg, Katja Zerbe, Mario Juhas, Laurent Bigler, Urs Stalder, Daniel Obrecht

Chembiochem· August 2012

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Peptidomimetic antibiotics target outer-membrane biogenesis in Pseudomonas aeruginosa.
Nityakalyani Srinivas, Peter Jetter, Bernhard J Ueberbacher, Martina Werneburg, Katja Zerbe, Daniel Obrecht

Science· February 2010

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The design, structures and therapeutic potential of protein epitope mimetics.
John A Robinson, Steve Demarco, Frank Gombert, Kerstin Moehle, Daniel Obrecht

Drug Discov Today· November 2008

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Molecular characterization of the NCoA-1-STAT 6 interaction.
Markus Seitz, Ludovic T Maillard, Daniel Obrecht, John A Robinson

Chembiochem· May 2008

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Biaryl amino acid templates in place of D-Pro-L-Pro in cyclic beta-hairpin cationic antimicrobial peptidomimetics.
Nityakalyani Srinivas, Kerstin Moehle, Khaled Abou-Hadeed, Daniel Obrecht, John A Robinson

Org Biomol Chem· October 2007

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Discovery of novel, highly potent and selective beta-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles.
Steven J DeMarco, Heiko Henze, Alexander Lederer, Kerstin Moehle, Reshmi Mukherjee, Jean-Pierre Obrecht, Daniel Obrecht

Bioorg Med Chem· December 2006

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Protein ligand design: from phage display to synthetic protein epitope mimetics in human antibody Fc-binding peptidomimetics.
Ricardo L A Dias, Rudi Fasan, Kerstin Moehle, Annabelle Renard, Daniel Obrecht

J Am Chem Soc· March 2006

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Structure-activity studies in a family of beta-hairpin protein epitope mimetic inhibitors of the p53-HDM2 protein-protein interaction.
Rudi Fasan, Ricardo L A Dias, Kerstin Moehle, Oliver Zerbe, Daniel Obrecht

Chembiochem· March 2006

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Properties and structure-activity studies of cyclic beta-hairpin peptidomimetics based on the cationic antimicrobial peptide protegrin I.
John A Robinson, Sasalu C Shankaramma, Peter Jetter, Ursula Kienzl, Reto A Schwendener, Daniel Obrecht

Bioorg Med Chem· March 2005

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Using a beta-hairpin to mimic an alpha-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction.
Rudi Fasan, Ricardo L A Dias, Kerstin Moehle, Oliver Zerbe, Jan W Vrijbloed, Daniel Obrecht

Angew Chem Int Ed Engl· April 2004

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