Publications by authors named "Daniel P Becker"

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Bioisosteric replacement of pyridoxal-5'-phosphate to pyridoxal-5'-tetrazole targeting Bacillus subtilis GabR.
Nicholas E Kaley, Zachary J Liveris, Maxwell Moore, Cory T Reidl, Zdzislaw Wawrzak, Daniel P Becker

Protein Sci· January 2025

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Synthesis of Pyrazole-Based Inhibitors of the Bacterial Enzyme -Succinyl-l,l-2,6-Diaminopimelic Acid Desuccinylase (DapE) as Potential Antibiotics.
Thomas DiPuma, Emma H Kelley, Teerana Thabthimthong, Alayna Bland, Katherine Konczak, Daniel P Becker

Int J Mol Sci· December 2024

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Corrigendum: N -acetyl-L-ornithine deacetylase from and a ninhydrin-based assay to enable inhibitor identification.
Emma H Kelley, Jerzy Osipiuk, Malgorzata Korbas, Michael Endres, Alayna Bland, Daniel P Becker

Front Chem· August 2024

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-acetyl-L-ornithine deacetylase from and a ninhydrin-based assay to enable inhibitor identification.
Emma H Kelley, Jerzy Osipiuk, Malgorzata Korbas, Michael Endres, Alayna Bland, Daniel P Becker

Front Chem· July 2024

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Cyclobutanone Inhibitors of Diaminopimelate Desuccinylase (DapE) as Potential New Antibiotics.
Thahani S Habeeb Mohammad, Emma H Kelley, Cory T Reidl, Katherine Konczak, Megan Beulke, Daniel P Becker

Int J Mol Sci· January 2024

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Biochemical and Structural Analysis of the Bacterial Enzyme Succinyl-Diaminopimelate Desuccinylase (DapE) from .
Emma H Kelley, George Minasov, Katherine Konczak, Ludmilla Shuvalova, Joseph S Brunzelle, Daniel P Becker

ACS Omega· January 2024

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Mapping roles of active site residues in the acceptor site of the PA3944 Gcn5-related N-acetyltransferase enzyme.
Cillian Variot, Daniel Capule, Xhulio Arolli, Jackson Baumgartner, Cory Reidl, Daniel P Becker

Protein Sci· August 2023

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Synthesis and characterization of the N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE) alternate substrate analog N,N-dimethyl-l,l-SDAP.
Zachary J Liveris, Emma H Kelley, Emma Simmons, Katherine Konczak, Marlon R Lutz, Daniel P Becker

Bioorg Med Chem· August 2023

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New Boron Delivery Agents.
Annette G Beck-Sickinger, Daniel P Becker, Oksana Chepurna, Bhaskar Das, Sebastian Flieger

Cancer Biother Radiopharm· April 2023

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Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry.
Sebastian Flieger, Mao Takagaki, Natsuko Kondo, Marlon R Lutz, Yash Gupta, Daniel P Becker

Int J Mol Sci· April 2023

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Tetrazole-based inhibitors of the bacterial enzyme N-succinyl-l,l-2,6-diaminopimelic acid desuccinylase as potential antibiotics.
Thomas DiPuma, Teerana Thabthimthong, Emma H Kelley, Katherine Konczak, Megan Beulke, Daniel P Becker

Bioorg Med Chem Lett· March 2023

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In Silico Binding of 2-Aminocyclobutanones to SARS-CoV-2 Nsp13 Helicase and Demonstration of Antiviral Activity.
Thahani S Habeeb Mohammad, Yash Gupta, Cory T Reidl, Vlad Nicolaescu, Haley Gula, Daniel P Becker

Int J Mol Sci· March 2023

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Iron dysregulation in COVID-19 and reciprocal evolution of SARS-CoV-2: Natura nihil frustra facit.
Yash Gupta, Dawid Maciorowski, Brian Medernach, Daniel P Becker, Ravi Durvasula

J Cell Biochem· March 2022

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Repurposing Lansoprazole and Posaconazole to treat leishmaniasis: Integration of in vitro testing, pharmacological corroboration, and mechanisms of action.
Yash Gupta, Steven Goicoechea, Jesus G Romero, Raman Mathur, Thomas R Caulfield, Daniel P Becker

J Food Drug Anal· March 2022

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Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays.
Yash Gupta, Dawid Maciorowski, Samantha E Zak, Krysten A Jones, Rahul S Kathayat, Daniel P Becker

Methods· November 2021

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Cyclobutanone Inhibitor of Cobalt-Functionalized Metallo-γ-Lactonase AiiA with Cyclobutanone Ring Opening in the Active Site.
Cory T Reidl, Romila Mascarenhas, Thahani S Habeeb Mohammad, Marlon R Lutz, Pei W Thomas, Daniel P Becker

ACS Omega· June 2021

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Gcn5-Related Acetyltransferases (GNATs) With a Catalytic Serine Residue Can Play Ping-Pong Too.
Jackson T Baumgartner, Thahani S Habeeb Mohammad, Mateusz P Czub, Karolina A Majorek, Xhulio Arolli, Daniel P Becker

Front Mol Biosci· April 2021

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Atomic-Resolution 1.3 Å Crystal Structure, Inhibition by Sulfate, and Molecular Dynamics of the Bacterial Enzyme DapE.
Matthew Kochert, Boguslaw P Nocek, Thahani S Habeeb Mohammad, Elliot Gild, Kaitlyn Lovato, Daniel P Becker

Biochemistry· March 2021

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A Review of the Preclinical and Clinical Efficacy of Remdesivir, Hydroxychloroquine, and Lopinavir-Ritonavir Treatments against COVID-19.
Dawid Maciorowski, Samir Z El Idrissi, Yash Gupta, Brian J Medernach, Michael B Burns, Daniel P Becker

SLAS Discov· December 2020

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Carborane-Containing Matrix Metalloprotease (MMP) Ligands as Candidates for Boron Neutron-Capture Therapy (BNCT).
Marlon R Lutz, Sebastian Flieger, Andre Colorina, John Wozny, Narayan S Hosmane, Daniel P Becker

ChemMedChem· October 2020

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Indoline-6-Sulfonamide Inhibitors of the Bacterial Enzyme DapE.
Cory T Reidl, Tahirah K Heath, Iman Darwish, Rachel M Torrez, Maxwell Moore, Daniel P Becker

Antibiotics (Basel)· September 2020

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(S)-4-Amino-5-phenoxypentanoate designed as a potential selective agonist of the bacterial transcription factor GabR.
Daniel S Catlin, Cory T Reidl, Thomas R Trzupek, Richard B Silverman, Brian L Cannon, Daniel P Becker

Protein Sci· August 2020

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A Gcn5-Related N-Acetyltransferase (GNAT) Capable of Acetylating Polymyxin B and Colistin Antibiotics in Vitro.
Mateusz P Czub, Brian Zhang, M Paul Chiarelli, Karolina A Majorek, Layton Joe, Daniel P Becker

Biochemistry· December 2018

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Iron(II) complexes of dimethyltriazacyclophane.
Wei Tsung Lee, Matthias Zeller, David Upp, Yuliya Politanska, Doug Steinman, Daniel P Becker

Acta Crystallogr C Struct Chem· December 2018

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Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target.
Tahirah K Heath, Marlon R Lutz, Cory T Reidl, Estefany R Guzman, Claire A Herbert, Daniel P Becker

PLoS One· July 2018

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