Publications by authors named "Daniel R Engel"

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SCAMP3 is essential for proper formation and function of neutrophil granules.
Almke Bader, Jincheng Gao, Nina Reiter, Devon Siemes, Annette Zehrer, Daniel Robert Engel

J Leukoc Biol· December 2025

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G-CSF/NAMPT signaling drives neutrophil dysfunction and enhances bacterial infection susceptibility in cancer patients.
Ekaterina Pylaeva, Lea Tollrian, Jana Riedesel, Olga Shevchuk, Ilona Thiel, Daniel Robert Engel

Nat Commun· December 2025

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Interleukin-1α alters megakaryocyte maturation, promotes emperipolesis, and induces a distinct proteomic profile.
Robert Kolman, Hannah Voß, Ivana Bertović, Josip Peradinović, Ivana Munitić, Daniel Robert Engel

J Thromb Haemost· September 2025

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A reference database enabling in-depth proteome and PTM analysis of mouse immune cells.
Devon Siemes, Hannah Voss, Federica Benvenuti, Francesca Simoncello, Dominik Kopczynski, Daniel Robert Engel

Sci Data· April 2025

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Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanoma.
Jan-Malte Placke, Jenny Bottek, Renata Váraljai, Batool Shannan, Sarah Scharfenberg, Daniel R Engel

Br J Dermatol· February 2025

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Inhibition of tumour necrosis factor alpha by Etanercept attenuates Shiga toxin-induced brain pathology.
Robin Christ, Devon Siemes, Shuo Zhao, Lars Widera, Philippa Spangenberg, Daniel R Engel

J Neuroinflammation· February 2025

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msiFlow: automated workflows for reproducible and scalable multimodal mass spectrometry imaging and microscopy data analysis.
Philippa Spangenberg, Sebastian Bessler, Lars Widera, Jenny Bottek, Mathis Richter, Daniel R Engel

Nat Commun· January 2025

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Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice.
Christina Wenzek, Devon Siemes, G Sebastian Hönes, Eva Pastille, Nina Härting, Daniel R Engel

iScience· August 2024

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Scientific Advances in Understanding the Pathogenesis, Diagnosis, and Prevention of Urinary Tract Infection in the Past 10 Years.
Daniel R Engel, Florian M E Wagenlehner, Olga Shevchuk

Infect Dis Clin North Am· June 2024

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Canonical and Noncanonical Contribution of Thyroid Hormone Receptor Isoforms Alpha and Beta to Cardiac Hypertrophy and Heart Rate in Male Mice.
Daniela Geist, Georg Sebastian Hönes, Susanne Camilla Grund, Janina Pape, Devon Siemes, Daniel Robert Engel

Thyroid· June 2024

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Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion.
Ali A Tuz, Susmita Ghosh, Laura Karsch, Dimitris Ttoouli, Sai P Sata, Daniel R Engel

Nat Cardiovasc Res· May 2024

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The global burden of antimicrobial resistance - urinary tract infections.
Sibylle Von Vietinghoff, Olga Shevchuk, Ulrich Dobrindt, Daniel Robert Engel, Selina K Jorch

Nephrol Dial Transplant· March 2024

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Correlation of tumor PD-L1 expression in different tissue types and outcome of PD-1-based immunotherapy in metastatic melanoma - analysis of the DeCOG prospective multicenter cohort study ADOREG/TRIM.
Jan-Malte Placke, Mona Kimmig, Klaus Griewank, Rudolf Herbst, Patrick Terheyden, Daniel Robert Engel

EBioMedicine· October 2023

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Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infection.
Kristina Zec, Stephanie Thiebes, Jenny Bottek, Devon Siemes, Philippa Spangenberg, Daniel R Engel

Front Immunol· October 2023

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Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function.
Devon Siemes, Pieter Vancamp, Boyka Markova, Philippa Spangenberg, Olga Shevchuk, Daniel Robert Engel

Cells· October 2023

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Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma.
Renáta Váraljai, Lisa Zimmer, Yahya Al-Matary, Paulien Kaptein, Lea J Albrecht, Daniel R Engel

Nat Cancer· September 2023

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Author Correction: Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma.
Renáta Váraljai, Lisa Zimmer, Yahya Al-Matary, Paulien Kaptein, Lea J Albrecht, Daniel R Engel

Nat Cancer· September 2023

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Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs.
Xiaoqing Xie, Pradeep Kumar Patnana, Daria Frank, Judith Schütte, Yahya Al-Matary, Daniel R Engel

Front Cell Dev Biol· April 2023

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Rapid and fully automated blood vasculature analysis in 3D light-sheet image volumes of different organs.
Philippa Spangenberg, Nina Hagemann, Anthony Squire, Nils Förster, Sascha D Krauß, Daniel R Engel

Cell Rep Methods· March 2023

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Non-invasive mapping of systemic neutrophil dynamics upon cardiovascular injury.
Pascal Bouvain, Zhaoping Ding, Shiwa Kadir, Patricia Kleimann, Nils Kluge, Daniel Robert Engel

Nat Cardiovasc Res· February 2023

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Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures.
Susanne Fleig, Tamar Kapanadze, Jeremiah Bernier-Latmani, Julia K Lill, Tania Wyss, Daniel R Engel

Nat Commun· April 2022

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The interplay of thyroid hormones and the immune system - where we stand and why we need to know about it.
Christina Wenzek, Anita Boelen, Astrid M Westendorf, Daniel R Engel, Lars C Moeller

Eur J Endocrinol· March 2022

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Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.
Phyllis F Cheung, JiaJin Yang, Rui Fang, Arianna Borgers, Kirsten Krengel, Daniel R Engel

Nat Commun· January 2022

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Eosinophils Suppress the Migration of T Cells Into the Brain of -Infected Mice and Protect Them From Experimental Cerebral Malaria.
Johanna F Scheunemann, Julia J Reichwald, Patricia Jebett Korir, Janina M Kuehlwein, Lea-Marie Jenster, Daniel R Engel

Front Immunol· December 2021

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Digital Quantification of Tumor PD-L1 Predicts Outcome of PD-1-Based Immune Checkpoint Therapy in Metastatic Melanoma.
Jan-Malte Placke, Camille Soun, Jenny Bottek, Rudolf Herbst, Patrick Terheyden, Daniel Robert Engel

Front Oncol· September 2021

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