Publications by authors named "Daniel Sevin"

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Mass-Guided Single-Cell MALDI Imaging of Low-Mass Metabolites Reveals Cellular Activation Markers.
James L Cairns, Johanna Huber, Andrea Lewen, Jessica Jung, Stefan J Maurer, Daniel Sevin

Adv Sci (Weinh)· February 2025

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Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation.
Anna Rutkowska, H Christian Eberl, Thilo Werner, Marco L Hennrich, Daniel C Sévin

Cancer Res Commun· September 2024

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Integrated metabolic-transcriptomic network identifies immunometabolic modulations in human macrophages.
Hung-Jen Chen, Daniel C Sévin, Guillermo R Griffith, Johanna Vappiani, Lee M Booty

Cell Rep· September 2024

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Consistency across multi-omics layers in a drug-perturbed gut microbial community.
Sander Wuyts, Renato Alves, Maria Zimmermann-Kogadeeva, Suguru Nishijima, Sonja Blasche, Daniel C Sevin

Mol Syst Biol· September 2023

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Metabolic rewiring revealed by cell-specific rate analyses from nontargeted exometabolomics during simultaneous consumption of glucose and lactic acid in a CHO fed-batch process.
Yu Luo, Johanna Vappiani, Keegan Orzechowski, Pramthesh Patel, Daniel Sevin

J Biotechnol· November 2022

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Exometabolome profiling reveals activation of the carnitine buffering pathway in fed-batch cultures of CHO cells co-fed with glucose and lactic acid.
Johanna Vappiani, Tom Eyster, Keegan Orzechowski, Diana Ritz, Pramthesh Patel

Biotechnol Prog· November 2021

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Metabolic memory underlying minimal residual disease in breast cancer.
Ksenija Radic Shechter, Eleni Kafkia, Katharina Zirngibl, Sylwia Gawrzak, Ashna Alladin

Mol Syst Biol· October 2021

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Bioaccumulation of therapeutic drugs by human gut bacteria.
Martina Klünemann, Sergej Andrejev, Sonja Blasche, Andre Mateus, Prasad Phapale

Nature· September 2021

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New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids.
Daniela Rodrigues, Terezinha de Souza, Luke Coyle, Matteo Di Piazza, Bram Herpers

Arch Toxicol· August 2021

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An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in human precision-cut lung slices.
Muzamil Majid Khan, Daniel Poeckel, Aliaksandr Halavatyi, Joanna Zukowska-Kasprzyk, Frank Stein, Daniel C Sevin

Eur Respir J· July 2021

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Effect of topical applications of sunflower seed oil on systemic fatty acid levels in under-two children under rehabilitation for severe acute malnutrition in Bangladesh: a randomized controlled trial.
K M Shahunja, Daniel C Sévin, Lindsay Kendall, Tahmeed Ahmed, Md Iqbal Hossain

Nutr J· June 2021

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Complementary NAD replacement strategies fail to functionally protect dystrophin-deficient muscle.
David W Frederick, Alan V McDougal, Melisa Semenas, Johanna Vappiani, Andrea Nuzzo

Skelet Muscle· October 2020

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Identifying drug targets in tissues and whole blood with thermal-shift profiling.
Jessica Perrin, Thilo Werner, Nils Kurzawa, Anna Rutkowska, Dorothee D Childs, Daniel C Sevin

Nat Biotechnol· March 2020

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Characterization of the small flavin-binding dodecin in the roseoflavin producer Streptomyces davawensis.
Petra Ludwig, Daniel C Sévin, Tobias Busche, Jörn Kalinowski, Florian Bourdeaux

Microbiology (Reading)· June 2018

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An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation.
Richard G Carroll, Zbigniew Zasłona, Silvia Galván-Peña, Emma L Koppe, Daniel C Sévin

J Biol Chem· April 2018

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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon

Nature· April 2018

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Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow.
Olga Ponomarova, Natalia Gabrielli, Daniel C Sévin, Michael Mülleder, Katharina Zirngibl

Cell Syst· October 2017

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Metabolic network segmentation: A probabilistic graphical modeling approach to identify the sites and sequential order of metabolic regulation from non-targeted metabolomics data.
Andreas Kuehne, Urs Mayr, Daniel C Sévin, Manfred Claassen, Nicola Zamboni

PLoS Comput Biol· June 2017

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Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli.
Daniel C Sévin, Tobias Fuhrer, Nicola Zamboni, Uwe Sauer

Nat Methods· February 2017

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Genomewide landscape of gene-metabolome associations in Escherichia coli.
Tobias Fuhrer, Mattia Zampieri, Daniel C Sévin, Uwe Sauer, Nicola Zamboni

Mol Syst Biol· January 2017

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Global Metabolic Responses to Salt Stress in Fifteen Species.
Daniel C Sévin, Jacqueline N Stählin, Georg R Pollak, Andreas Kuehne, Uwe Sauer

PLoS One· July 2016

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Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.
Shahaf Peleg, Christian Feller, Ignasi Forne, Evelyn Schiller, Daniel C Sévin

EMBO Rep· March 2016

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A dual control mechanism synchronizes riboflavin and sulphur metabolism in Bacillus subtilis.
Danielle Biscaro Pedrolli, Christian Kühm, Daniel C Sévin, Michael P Vockenhuber, Uwe Sauer

Proc Natl Acad Sci U S A· November 2015

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Inflating bacterial cells by increased protein synthesis.
Markus Basan, Manlu Zhu, Xiongfeng Dai, Mya Warren, Daniel Sévin

Mol Syst Biol· October 2015

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