Publications by authors named "Daniel Simao"

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Addressing neuroinflammation in human induced pluripotent stem cell-derived central nervous system neurospheroids.
Catarina M Gomes, Daniel Simão, Carolina Cardoso Gonçalves, Gabriela Silva, Beatriz Painho

iScience· September 2025

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Aldehyde Dehydrogenase 2 (ALDH2): A novel sorafenib target in hepatocellular carcinoma unraveled by the proteome-wide cellular thermal shift assay.
Inês C Ferreira, Estefania Torrejón, Bernardo Abecasis, Bruno M Alexandre, Ricardo A Gomes

SLAS Discov· April 2024

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Miniaturization of hiPSC-derived 3D neural cultures in stirred-tank bioreactors for parallelized preclinical assessment of rAAV.
Catarina M Gomes, Maria João Sebastião, Gabriela Silva, Filipa Moura, Daniel Simão

Front Bioeng Biotechnol· April 2024

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Novel scFv against Notch Ligand JAG1 Suitable for Development of Cell Therapies toward JAG1-Positive Tumors.
Gabriela Silva, Ana F Rodrigues, Susana Ferreira, Carolina Matos, Rute P Eleutério

Biomolecules· March 2023

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Transcriptome and proteome profiling of activated cardiac fibroblasts supports target prioritization in cardiac fibrosis.
Maria Raquel Moita, Marta M Silva, Cláudia Diniz, Margarida Serra, René M Hoet

Front Cardiovasc Med· December 2022

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Capturing the third dimension in drug discovery: Spatially-resolved tools for interrogation of complex 3D cell models.
Daniel Simão, Catarina M Gomes, Paula M Alves, Catarina Brito

Biotechnol Adv· May 2022

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Unveiling dynamic metabolic signatures in human induced pluripotent and neural stem cells.
João Vasconcelos E Sá, Daniel Simão, Ana P Terrasso, Marta M Silva, Catarina Brito

PLoS Comput Biol· April 2020

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Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Hepatic Infection.
Francisca Arez, Sofia P Rebelo, Diana Fontinha, Daniel Simão, Tatiana R Martins

ACS Infect Dis· November 2019

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Full-length human CCBE1 production and purification: leveraging bioprocess development for high quality glycosylation attributes and functionality.
Marta M Silva, Patrícia Gomes-Alves, Sara Rosa, Daniel Simão, José M Inácio

J Biotechnol· November 2018

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Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons.
Neus Bayó-Puxan, Ana Paula Terrasso, Sophie Creyssels, Daniel Simão, Christina Begon-Pescia

Sci Rep· November 2018

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Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation.
Daniel Simão, Marta M Silva, Ana P Terrasso, Francisca Arez, Marcos F Q Sousa

Stem Cell Reports· August 2018

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Perfusion Stirred-Tank Bioreactors for 3D Differentiation of Human Neural Stem Cells.
Daniel Simão, Francisca Arez, Ana P Terasso, Catarina Pinto, Marcos F Q Sousa

Methods Mol Biol· January 2018

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Energy-Efficient Channel Coding Strategy for Underwater Acoustic Networks.
Grasielli Barreto, Daniel H Simão, Marcelo E Pellenz, Richard D Souza, Edgard Jamhour

Sensors (Basel)· March 2017

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Functional metabolic interactions of human neuron-astrocyte 3D in vitro networks.
Daniel Simão, Ana P Terrasso, Ana P Teixeira, Catarina Brito, Ursula Sonnewald

Sci Rep· September 2016

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Transcriptional Response of Human Neurospheres to Helper-Dependent CAV-2 Vectors Involves the Modulation of DNA Damage Response, Microtubule and Centromere Gene Groups.
Stefania Piersanti, Romina Burla, Valerio Licursi, Catarina Brito, Mattia La Torre, Daniel Simao

PLoS One· May 2016

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Human amniocyte-derived cells are a promising cell host for adenoviral vector production under serum-free conditions.
Ana Carina Silva, Daniel Simão, Claudia Küppers, Tanja Lucas, Marcos F Q Sousa

Biotechnol J· May 2015

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Towards human central nervous system in vitro models for preclinical research: strategies for 3D neural cell culture.
Daniel Simão, Inês Costa, Margarida Serra, Johannes Schwarz, Catarina Brito

BMC Proc· April 2015

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Modeling human neural functionality in vitro: three-dimensional culture for dopaminergic differentiation.
Daniel Simão, Catarina Pinto, Stefania Piersanti, Anne Weston, Christopher J Peddie

Tissue Eng Part A· February 2015

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Imaging of human differentiated 3D neural aggregates using light sheet fluorescence microscopy.
Emilio J Gualda, Daniel Simão, Catarina Pinto, Paula M Alves, Catarina Brito

Front Cell Neurosci· August 2014

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3D cultures of human neural progenitor cells: dopaminergic differentiation and genetic modification. [corrected].
Catarina Brito, Daniel Simão, Inês Costa, Rita Malpique, Cristina I Pereira

Methods· March 2012

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Gene stage-specific expression in the microenvironment of pediatric myelodysplastic syndromes.
Rosimeire A Roela, Dirce M Carraro, Helena P Brentani, Jane H L Kaiano, Daniel F Simão

Leuk Res· May 2007

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Class distinction between follicular adenomas and follicular carcinomas of the thyroid gland on the basis of their signature expression.
Beatriz S Stolf, Mariana M S Santos, Daniel F Simao, Juan P Diaz, Elier B Cristo

Cancer· May 2006

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