Publications by authors named "Daniel Sirkis"

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DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.
Luke W Bonham, Daniel W Sirkis, Alina P S Pang, Leo P Sugrue, Hernando Santamaría-García

NPJ Dement· May 2025

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Reduced levels of angiogenesis biomarkers predict increased symptom severity in Chinese Americans with Alzheimer's disease with demographic-specific effect.
Taylor P Johnson, Elena Tsoy, Jeffrey Shen, Will Rivera, Kevin Lieu, Daniel W Sirkis

Neurocase· April 2025

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The role of interferon signaling in neurodegeneration and neuropsychiatric disorders.
Daniel W Sirkis, Alexis P Oddi, Caroline Jonson, Luke W Bonham, Phuong T Hoang

Front Psychiatry· October 2024

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DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.
Luke Bonham, Daniel Sirkis, Alina Pang, Leo Sugrue, Hernando Santamaría-García

Res Sq· October 2024

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Frontotemporal lobar degeneration targets brain regions linked to expression of recently evolved genes.
Lorenzo Pasquini, Felipe L Pereira, Sahba Seddighi, Yi Zeng, Yongbin Wei, Daniel W Sirkis

Brain· September 2024

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Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease.
Daniel W Sirkis, Caroline Warly Solsberg, Taylor P Johnson, Luke W Bonham, Alexis P Oddi

Alzheimers Dement· July 2024

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gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types.
Iris J Broce, Daniel W Sirkis, Ryan M Nillo, Luke W Bonham, Suzee E Lee

Front Neurosci· February 2024

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Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease.
Daniel W Sirkis, Caroline Warly Solsberg, Taylor P Johnson, Luke W Bonham, Alexis P Oddi

bioRxiv· January 2024

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FTLD targets brain regions expressing recently evolved genes.
Lorenzo Pasquini, Felipe L Pereira, Sahba Seddighi, Yi Zeng, Yongbin Wei, Daniel W Sirkis

medRxiv· October 2023

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Frontotemporal dementia presentation in patients with heterozygous p.H157Y variant of .
Natalia Ogonowski, Hernando Santamaria-Garcia, Sandra Baez, Andrea Lopez, Andrés Laserna, Daniel W Sirkis

J Med Genet· September 2023

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Role for cell death pathway in Alzheimer's disease.
Daniel W Sirkis, Jennifer S Yokoyama

Science· September 2023

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Early-onset Alzheimer's disease explained by polygenic risk of late-onset disease?
William G Mantyh, J Nicholas Cochran, Jared W Taylor, Iris J Broce, Ethan G Geier, Daniel W Sirkis

Alzheimers Dement (Amst)· September 2023

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Critical metal geochemistry in groundwaters influenced by dredged material.
Aaron J Goodman, Austin Scircle, Ashley Kimble, William Harris, Bailey Calvitti, Daniel Sirkis

Sci Total Environ· August 2023

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gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types.
Iris J Broce, Daniel W Sirkis, Ryan M Nillo, Luke W Bonham, Suzee E Lee

bioRxiv· August 2023

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Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy.
Daniel W Sirkis, Caroline Warly Solsberg, Taylor P Johnson, Luke W Bonham, Virginia E Sturm

Genome Med· July 2023

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Radiogenomics of Expansion Carriers Reveals Global Transposable Element Derepression and Enables Prediction of Thalamic Atrophy and Clinical Impairment.
Luke W Bonham, Ethan G Geier, Daniel W Sirkis, Josiah K Leong, Eliana Marisa Ramos

J Neurosci· January 2023

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Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers.
Shenjie Wu, Nancy C Hernandez Villegas, Daniel W Sirkis, Iona Thomas-Wright, Richard Wade-Martins

Elife· January 2023

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Dissecting the clinical heterogeneity of early-onset Alzheimer's disease.
Daniel W Sirkis, Luke W Bonham, Taylor P Johnson, Renaud La Joie, Jennifer S Yokoyama

Mol Psychiatry· June 2022

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The Role of Microglia in Inherited White-Matter Disorders and Connections to Frontotemporal Dementia.
Daniel W Sirkis, Luke W Bonham, Jennifer S Yokoyama

Appl Clin Genet· March 2021

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The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease.
Luke W Bonham, Daniel W Sirkis, Jennifer S Yokoyama

Front Immunol· October 2020

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The Radiogenomics of Late-onset Alzheimer Disease.
Luke W Bonham, Daniel W Sirkis, Christopher P Hess, Leo P Sugrue, Jennifer S Yokoyama

Top Magn Reson Imaging· December 2019

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Immunological signatures in frontotemporal lobar degeneration.
Daniel W Sirkis, Luke W Bonham, Celeste M Karch, Jennifer S Yokoyama

Curr Opin Neurol· April 2019

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Recent advances in the genetics of frontotemporal dementia.
Daniel W Sirkis, Ethan G Geier, Luke W Bonham, Celeste M Karch, Jennifer S Yokoyama

Curr Genet Med Rep· March 2019

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Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia.
Ethan G Geier, Mathieu Bourdenx, Nadia J Storm, J Nicholas Cochran, Daniel W Sirkis

Acta Neuropathol· January 2019

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Neurodegeneration-associated mutant TREM2 proteins abortively cycle between the ER and ER-Golgi intermediate compartment.
Daniel W Sirkis, Renan E Aparicio, Randy Schekman

Mol Biol Cell· October 2017

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