Publications by authors named "Daniel Stange"

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A biomaterial-based platform of pancreatic cancer reveals kallikrein-related peptidase 6 (KLK6) as a mediator of neutrophil recruitment and immunosuppression.
Verena J Kast, Sandra Hauser, Ali Nadernezhad, Dagmar Pette, Manfred F Maitz, Daniel E Stange

Biomaterials· January 2026

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Intratumoral regulatory T cells are associated with treatment response to neoadjuvant chemotherapy and prognosis in gastroesophageal adenocarcinoma.
Franziska Baenke, Antonia Stammberger, Ulrich Sommer, Sascha Brückmann, Felix Merboth, Daniel E Stange

Oncoimmunology· December 2025

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MCL1 modulates mTORC1 signaling to promote bioenergetics and tumorigenesis.
Wentao Gui, Petr Paral, Bhavuk Dhamija, Eman Hagag, Martin Dusa, Daniel E Stange

Nat Commun· December 2025

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Nectin-4 reduces T cell effector function and is a therapeutic target in pancreatic cancer.
Max Heiduk, Carolin Beer, Sarah Cronjaeger, Emily A Kawaler, Ulrich Sommer, Daniel E Stange

JCI Insight· December 2025

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Epithelial WNT secretion drives niche escape of developing gastric cancer.
Jaehun Lee, Soomin Kim, Youngchul Oh, Stephan R Jahn, Jihoon Kim, Daniel E Stange

Mol Cancer· December 2025

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Human assembloids recapitulate periportal liver tissue in vitro.
Lei Yuan, Sagarika Dawka, Yohan Kim, Anke Liebert, Fabian Rost, Daniel E Stange

Nature· December 2025

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Patient-specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity.
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Daniel Stange

Mol Oncol· September 2025

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Navigating ethical challenges across professions: Insights from an Ethics Lab on patient-derived organoids.
Jeanette Bresson Ladegaard Knox, Mie Seest Dam, Sara Green, Daniel E Stange, Franziska Baenke

Med· May 2025

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Molecular Spectroscopy for the Biochemical Composition Analysis of Patient-Derived Pancreatic Cancer Organoids.
Christian Teske, Katja Liedel, Alexander Hirle, Franziska Baenke, Daniel E Stange

Cancer Med· December 2024

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Stratifying esophago-gastric cancer treatment using a patient-derived organoid-based threshold.
Tim Schmäche, Juliane Fohgrub, Anna Klimova, Karin Laaber, Stephan Drukewitz, Daniel E Stange

Mol Cancer· January 2024

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Deep learning trained on lymph node status predicts outcome from gastric cancer histopathology: a retrospective multicentric study.
Hannah S Muti, Christoph Röcken, Hans-Michael Behrens, Chiara M L Löffler, Nic G Reitsam, Daniel E Stange

Eur J Cancer· November 2023

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A Tumor Microenvironment Model of Pancreatic Cancer to Elucidate Responses toward Immunotherapy.
Verena Kast, Ali Nadernezhad, Dagmar Pette, Anastasiia Gabrielyan, Maximilian Fusenig, Daniel E Stange

Adv Healthc Mater· June 2023

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CRISPR/Cas9 Screen in Gastric Cancer Patient-Derived Organoids Reveals KDM1A-NDRG1 Axis as a Targetable Vulnerability.
Jovan Mircetic, Aylin Camgöz, Moustafa Abohawya, Li Ding, Julia Dietzel, Daniel E Stange

Small Methods· June 2023

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Fast and label-free intraoperative discrimination of malignant pancreatic tissue by attenuated total reflection infrared spectroscopy.
Rimante Bandzeviciute, Gerald Steiner, Katja Liedel, Jonas Golde, Edmund Koch, Daniel E Stange

J Biomed Opt· April 2023

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Robotic Esophagectomy Compared With Open Esophagectomy Reduces Sarcopenia within the First Postoperative Year: A Propensity Score-Matched Analysis.
Felix Merboth, Heiner Nebelung, Natalie Wotschel, Hendrik Liebscher, Franziska Eckert, Daniel E Stange

J Thorac Oncol· February 2023

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Sensitivity towards HDAC inhibition is associated with RTK/MAPK pathway activation in gastric cancer.
Therese Seidlitz, Tim Schmäche, Fernando Garcίa, Joon Ho Lee, Nan Qin, Daniel E Stange

EMBO Mol Med· October 2022

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Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms.
Kristin Pape, Anna J Lößner, Doreen William, Tabea Czempiel, Elke Beyreuther, Daniel E Stange

Cancers (Basel)· October 2022

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Minimally invasivE versus open total GAstrectomy (MEGA): study protocol for a multicentre randomised controlled trial (DRKS00025765).
Felix Nickel, Alexander Studier-Fischer, David Hausmann, Rosa Klotz, Sophia Lara Vogel-Adigozalov, Daniel Stange

BMJ Open· October 2022

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Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing.
Shady Sayed, Olga A Sidorova, Alexander Hennig, Martina Augsburg, Catherine P Cortés Vesga, Daniel E Stange

Cancer Res· September 2022

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Detecting drug resistance in pancreatic cancer organoids guides optimized chemotherapy treatment.
Alexander Hennig, Franziska Baenke, Anna Klimova, Stephan Drukewitz, Beatrix Jahnke, Daniel E Stange

J Pathol· August 2022

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Combined Systemic Drug Treatment with Proton Therapy: Investigations on Patient-Derived Organoids.
Max Naumann, Tabea Czempiel, Anna Jana Lößner, Kristin Pape, Elke Beyreuther, Daniel E Stange

Cancers (Basel)· August 2022

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Robotic-assisted minimally invasive Ivor Lewis esophagectomy within the prospective multicenter German da Vinci Xi registry trial.
Jan-Hendrik Egberts, Thilo Welsch, Felix Merboth, Sandra Korn, Christian Praetorius, Daniel E Stange

Langenbecks Arch Surg· June 2022

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p57 imposes the reserve stem cell state of gastric chief cells.
Ji-Hyun Lee, Somi Kim, Seungmin Han, Jimin Min, Brianna Caldwell, Daniel E Stange

Cell Stem Cell· May 2022

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Stem Cells, Helicobacter pylori, and Mutational Landscape: Utility of Preclinical Models to Understand Carcinogenesis and to Direct Management of Gastric Cancer.
Dylan Liabeuf, Masanobu Oshima, Daniel E Stange, Michael Sigal

Gastroenterology· April 2022

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Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer.
Kenneth Peuker, Anne Strigli, Daniele V F Tauriello, Alexander Hendricks, Witigo von Schönfels, Daniel E Stange

Immunity· April 2022

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