Publications by authors named "Daniel Tyrrell"

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Mitochondrial Glycosylation in Neuroinflammation Models.
Meghana Madabhushi, Rachel Erin Murphy, Md Akkas Ali, Muthuvel Paneerselvam, Mallikarjun Hanamantagouda Patil, Daniel J Tyrrell

Cells Tissues Organs· December 2025

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High-Dimensional Single-Cell Analysis Reveals Coordinated Age-Dependent Neuroinflammatory Microglia-T cell Circuits in the Brain.
Md Akkas Ali, Md Hasanul Banna Siam, Donald Vardaman, Chase Bolding, J Nicholas Brazell, Daniel J Tyrrell

bioRxiv· December 2025

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Tau, amyloid-β and α-synuclein co-pathologies synergistically enhance neuroinflammation and neuropathology.
Jhodi M Webster, Ya-Ting Yang, Aidan T Miller, Asta Zane, Kasandra Scholz, Daniel J Tyrrell

bioRxiv· November 2025

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genotype negates the benefits of 17β-estradiol on cerebrovascular endothelial and mitochondrial function.
Mackenzie N Kehmeier, Alexandra Famiano, Abigail E Cullen, Thomas Leonhardt, Skylyn Ferguson, Daniel Tyrrell

bioRxiv· July 2025

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CAFE: an integrated web app for high-dimensional analysis and visualization in spectral flow cytometry.
Md Hasanul Banna Siam, Md Akkas Ali, Donald Vardaman, Satwik Acharyya, Mallikarjun Patil, Daniel J Tyrrell

Bioinformatics· June 2025

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Paradoxical SERCA2a Dysregulation Contributes to Atrial Fibrillation in a Model of Diet-Induced Obesity.
Daniela Ponce-Balbuena, Daniel J Tyrrell, Carlos Cruz-Cortés, Guadalupe Guerrero-Serna, Andre Monteiro Da Rocha

Int J Mol Sci· June 2025

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Mitochondrial Preparation from Microglia for Glycan Analysis.
Meghana Madabhushi, Tana V Palomino, Mallikarjun H Patil, David C Muddiman, Daniel J Tyrrell

J Vis Exp· May 2025

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Development of a Spectral Flow Cytometry Analysis Pipeline for High-dimensional Immune Cell Characterization.
Donald Vardaman, Md Akkas Ali, Md Hasanul Banna Siam, Chase Bolding, Harrison Tidwell, Daniel J Tyrrell

J Immunol· December 2024

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CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry.
Md Hasanul Banna Siam, Md Akkas Ali, Donald Vardaman, Satwik Acharyya, Mallikarjun Patil, Daniel J Tyrrell

bioRxiv· December 2024

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Publisher Correction: Clonally expanded memory CD8 T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice.
Daniel J Tyrrell, Kathleen M Wragg, Judy Chen, Hui Wang, Jianrui Song

Nat Aging· August 2024

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Paradoxical SERCA dysregulation contributes to atrial fibrillation in a model of diet-induced obesity.
Daniela Ponce-Balbuena, Daniel J Tyrrell, Carlos Cruz-Cortés, Guadalupe Guerrero-Serna, Andre Monteiro Da Rocha

bioRxiv· August 2024

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Tissue resident memory CD8+ T cells are present but not critical for demyelination and neurodegeneration in a mouse model of multiple system atrophy.
Nicole J Corbin-Stein, Gabrielle M Childers, Jhodi M Webster, Asta Zane, Ya-Ting Yang, Daniel J Tyrrell

bioRxiv· June 2024

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FGF receptors mediate cellular senescence in the cystic fibrosis airway epithelium.
Molly Easter, Meghan June Hirsch, Elex Harris, Patrick Henry Howze, Emma Lea Matthews, Daniel J Tyrrell

JCI Insight· June 2024

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Development of a Spectral Flow Cytometry Analysis Pipeline for High-Dimensional Immune Cell Characterization.
Donald Vardaman, Md Akkas Ali, Chase Bolding, Harrison Tidwell, Holly Stephens, Daniel J Tyrrell

bioRxiv· June 2024

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Cardiovascular aging: spotlight on mitochondria.
Md Akkas Ali, Rachel Gioscia-Ryan, Dongli Yang, Nadia R Sutton, Daniel J Tyrrell

Am J Physiol Heart Circ Physiol· February 2024

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Analysis of NIH K99/R00 awards and the career progression of awardees.
Nicole C Woitowich, Sarah R Hengel, Christopher Solis, Tauras P Vilgalys, Joel Babdor, Daniel J Tyrrell

Elife· January 2024

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Analysis of NIH K99/R00 Awards and the Career Progression of Awardees.
Nicole C Woitowich, Sarah R Hengel, Christopher Solis, Tauras P Vilgalys, Joel Babdor, Daniel J Tyrrell

bioRxiv· December 2023

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Clonally expanded memory CD8 T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice.
Daniel J Tyrrell, Kathleen M Wragg, Judy Chen, Hui Wang, Jianrui Song

Nat Aging· December 2023

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Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice.
Jianrui Song, Yanling Zhang, Ryan A Frieler, Anthony Andren, Sherri Wood, Daniel J Tyrrell

J Clin Invest· December 2023

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Senescence and Inflammation: Summary of a Gerontological Society of America and National Institute on Aging-Sponsored Symposium.
Xu Zhang, Daniel J Tyrrell, Tamara Alliston, Birgit Schilling, Matthew J Yousefzadeh

J Gerontol A Biol Sci Med Sci· October 2023

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Age-associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis.
Jianrui Song, Diana Farris, Paola Ariza, Smriti Moorjani, Mita Varghese, Daniel Tyrrell

Aging Cell· February 2023

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Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis.
George Hindy, Daniel J Tyrrell, Alexi Vasbinder, Changli Wei, Feriel Presswalla

J Clin Invest· December 2022

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Black In Cardio: promoting diversity and representation in the cardiovascular field.
Jason Amartey, Chichi Okagbue, Adama Saccoh, Stanley Buffonge, Ashley Francois, Daniel J Tyrrell

Nat Rev Cardiol· November 2022

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Aging Alters the Aortic Proteome in Health and Thoracic Aortic Aneurysm.
Daniel J Tyrrell, Judy Chen, Benjamin Y Li, Sherri C Wood, Wendy Rosebury-Smith

Arterioscler Thromb Vasc Biol· August 2022

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Aging Impairs Mitochondrial Function and Mitophagy and Elevates Interleukin 6 Within the Cerebral Vasculature.
Daniel J Tyrrell, Muriel G Blin, Jianrui Song, Sherri C Wood, Daniel R Goldstein

J Am Heart Assoc· December 2020

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