Publications by authors named "Daniel Worthley"

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Evolutionary adaptation of probiotics in the gut: selection pressures, optimization strategies, and regulatory challenges.
Julia Leeflang, Josephine A Wright, Daniel L Worthley, M Omar Din, Susan L Woods

NPJ Biofilms Microbiomes· June 2025

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Prostaglandin E and Akt Promote Stemness in Apc Mutant Dclk1+ Cells to Give Rise to Colitis-associated Cancer.
Hayley J Good, Frederikke Larsen, Alice E Shin, Liyue Zhang, Mathieu Derouet, Daniel Worthley

Cell Mol Gastroenterol Hepatol· May 2025

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Stem cell injections for osteoarthritis of the knee.
Samuel L Whittle, Renea V Johnston, Steve McDonald, Daniel Worthley, T Mark Campbell

Cochrane Database Syst Rev· April 2025

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Discovery of WEE1 Kinase Inhibitors with Potent Activity against Patient-Derived, Metastatic Colorectal Cancer Organoids.
Joel L Syphers, Josephine A Wright, Shen Liu, Yi Sing Gee, Fan Gao, Daniel L Worthley

J Med Chem· April 2025

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Neuro-Mesenchymal Interaction Mediated by a β2-Adrenergic Nerve Growth Factor Feedforward Loop Promotes Colorectal Cancer Progression.
Hiroki Kobayashi, Tadashi Iida, Yosuke Ochiai, Ermanno Malagola, Xiaofei Zhi, Daniel L Worthley

Cancer Discov· January 2025

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Impaired Glycosylation of Gastric Mucins Drives Gastric Tumorigenesis and Serves as a Novel Therapeutic Target.
Junya Arai, Yoku Hayakawa, Hiroaki Tateno, Keita Murakami, Takeru Hayashi, Daniel L Worthley

Gastroenterology· August 2024

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Towards Understanding Tumour Colonisation by Probiotic Bacterium Nissle 1917.
Georgette A Radford, Laura Vrbanac, Rebekah T de Nys, Daniel L Worthley, Josephine A Wright

Cancers (Basel)· August 2024

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Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia.
Candice R Gurbatri, Georgette A Radford, Laura Vrbanac, Jongwon Im, Elaine M Thomas, Daniel L Worthley

Nat Commun· January 2024

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Advancing translational research for colorectal immuno-oncology.
Elaine M Thomas, Josephine A Wright, Stephen J Blake, Amanda J Page, Daniel L Worthley

Br J Cancer· October 2023

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Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis.
Jia Q Ng, Toghrul H Jafarov, Christopher B Little, Tongtong Wang, Abdullah M Ali, Daniel L Worthley

Nat Commun· October 2023

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Engineered bacteria detect tumor DNA.
Robert M Cooper, Josephine A Wright, Jia Q Ng, Jarrad M Goyne, Nobumi Suzuki, Daniel L Worthley

Science· August 2023

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Colorectal cancer detection and treatment with engineered probiotics.
Candice R Gurbatri, Georgette Radford, Laura Vrbanac, Courtney Coker, Jong-Won Im, Daniel L Worthley

bioRxiv· April 2023

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Non- Gastric Microbiome Modulates Prooncogenic Responses and Is Associated With Gastric Cancer Risk.
Ryota Niikura, Yoku Hayakawa, Naoyoshi Nagata, Tohru Miyoshi-Akiayama, Koji Miyabayashi, Daniel L Worthley

Gastro Hep Adv· March 2023

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Loss of -articular cartilage progenitor cells causes osteoarthritis.
Jia Q Ng, Toghrul H Jafarov, Christopher B Little, Tongtong Wang, Abdullah Ali, Daniel L Worthley

bioRxiv· March 2023

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The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.
Hiroki Kobayashi, Krystyna A Gieniec, Tamsin R M Lannagan, Tongtong Wang, Naoya Asai, Daniel L Worthley

Gastroenterology· March 2022

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The clinical value of "exception item" colonoscopy (MBS item 32228).
Michelle Lee See, Antonio Lee, Roderick Roberts, Richard A Friedman, David G Hewett, Daniel L Worthley

Med J Aust· February 2022

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The Antianginal Drug Perhexiline Displays Cytotoxicity against Colorectal Cancer Cells In Vitro: A Potential for Drug Repurposing.
Bimala Dhakal, Celine Man Ying Li, Runhao Li, Kenny Yeo, Josephine A Wright, Daniel L Worthley

Cancers (Basel)· February 2022

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Desmopressin as a Novel Long-Term Treatment in Postural Tachycardia Syndrome Patients with Polyuria.
Marie-Claire Seeley, Tilenka R Thynne, Wilton J Braund, Daniel L Worthley, Celine Gallagher

Am J Med· September 2021

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Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma.
Hiroki Kobayashi, Krystyna A Gieniec, Jia Q Ng, Jarrad Goyne, Tamsin R M Lannagan, Daniel L Worthley

J Vis Exp· September 2021

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The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses.
Mari Ichinose, Nobumi Suzuki, Tongtong Wang, Hiroki Kobayashi, Laura Vrbanac, Daniel L Worthley

Development· July 2021

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Stromal DLK1 promotes proliferation and inhibits differentiation of the intestinal epithelium during development.
Mari Ichinose, Nobumi Suzuki, Tongtong Wang, Josephine A Wright, Tamsin R M Lannagan, Daniel L Worthley

Am J Physiol Gastrointest Liver Physiol· April 2021

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The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis.
Hiroki Kobayashi, Krystyna A Gieniec, Josephine A Wright, Tongtong Wang, Naoya Asai, Daniel L Worthley

Gastroenterology· March 2021

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Delineating proinflammatory microenvironmental signals by ex vivo modeling of the immature intestinal stroma.
Mari Ichinose, Nobumi Suzuki, Tongtong Wang, Josephine A Wright, Tamsin R M Lannagan, Daniel L Worthley

Sci Rep· March 2021

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Young-onset colorectal cancer is associated with a personal history of type 2 diabetes.
Reger R Mikaeel, Erin L Symonds, James Kimber, Eric Smith, Mehgan Horsnell, Daniel L Worthley

Asia Pac J Clin Oncol· February 2021

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Targeted Disruption of Bone Marrow Stromal Cell-Derived Gremlin1 Limits Multiple Myeloma Disease Progression In Vivo.
Kimberley C Clark, Duncan R Hewett, Vasilios Panagopoulos, Natalya Plakhova, Khatora S Opperman, Daniel L Worthley

Cancers (Basel)· August 2020

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