Publications by authors named "Daniel Z Doherty"

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Evolutionary insights into the selectivity of sterol oxidising cytochrome P450 enzymes based on ancestral sequence reconstruction.
Daniel Z Doherty, James J De Voss, John B Bruning, Stephen G Bell

Chem Sci· June 2025

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Structural and Energetic Evidence Supports the Non-Covalent Phosphate Cyclization by the Class II Phospholipase D from .
Carolina Gismene, José Fernando Ruggiero Bachega, Daniel Z Doherty, Silvio Sanches Veiga, Raghuvir K Arni

Toxins (Basel)· February 2025

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Synthesis of steroidal inhibitors for Mycobacterium tuberculosis.
Luke R Churchman, James R Beckett, Lendl Tan, Kyra Woods, Daniel Z Doherty

J Steroid Biochem Mol Biol· May 2024

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Structural determination and characterisation of the CYP105Q4 cytochrome P450 enzyme from Mycobacterium marinum.
Hebatalla Mohamed, Stella A Child, Daniel Z Doherty, John B Bruning, Stephen G Bell

Arch Biochem Biophys· April 2024

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Computational methods meet in vitro techniques: A case study on fusaric acid and its possible detoxification through cytochrome P450 enzymes.
Lorenzo Pedroni, Daniel Zocchi Doherty, Chiara Dall'Asta, Gianni Galaverna, Stephen G Bell

Ecotoxicol Environ Saf· March 2024

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Characterisation of the heme aqua-ligand coordination environment in an engineered peroxygenase cytochrome P450 variant.
Matthew N Podgorski, Joel H Z Lee, Joshua S Harbort, Giang T H Nguyen, Daniel Z Doherty

J Inorg Biochem· December 2023

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The bacterial cytochrome P450 (CYP) CYP125 enzymes can competitively oxidise sitosterol in the presence of cholesterol.
Daniel Z Doherty, Amna Ghith, Ava Ho, James J De Voss, Stephen G Bell

Chem Commun (Camb)· July 2023

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Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering.
Tom Coleman, Joel Z H Lee, Alicia M Kirk, Daniel Z Doherty, Matthew N Podgorski

Chemistry· December 2022

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Exploring the Factors which Result in Cytochrome P450 Catalyzed Desaturation Versus Hydroxylation.
Tom Coleman, Daniel Z Doherty, Ting Zhang, Matthew N Podgorski, Ruihong Qiao

Chem Asian J· December 2022

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The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from and .
Amna Ghith, Daniel Z Doherty, John B Bruning, Robert A Russell, James J De Voss

ACS Infect Dis· August 2022

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