Publications by authors named "Daniela Rotin"

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The ubiquitin ligase Nedd4-2 promotes localization of DNMBP/Tuba to P-bodies under hyperosmotic stress.
Zetao Liu, Chong Jiang, Faith Yeung, Brian Raught, Daniela Rotin

J Biol Chem· November 2025

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The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation.
Yu-Xi Xiao, Seon Yong Lee, Magali Aguilera-Uribe, Reuben Samson, Aaron Au, Daniela Rotin

Cell Rep· July 2024

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Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2.
Daniela Rotin, Gali Prag

Physiology (Bethesda)· January 2024

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Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity.
Bekir Altas, Hong-Jun Rhee, Anes Ju, Hugo Cruces Solís, Samir Karaca, Daniela Rotin

J Cell Biol· January 2024

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Primate-specific isoform of Nedd4-1 regulates substrate binding via Ser/Thr phosphorylation and 14-3-3 binding.
George Kefalas, Daniela Rotin

Sci Rep· October 2023

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Regulation of the p38-MAPK pathway by hyperosmolarity and by WNK kinases.
Zetao Liu, Wael Demian, Avinash Persaud, Chong Jiang, Arohan R Subramanaya, Daniela Rotin

Sci Rep· August 2022

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Elevated intracellular Na and osmolarity stimulate catalytic activity of the ubiquitin ligase Nedd4-2.
Avinash Persaud, Chong Jiang, Zetao Liu, George Kefalas, Wael L Demian, Daniela Rotin

Proc Natl Acad Sci U S A· July 2022

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High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids.
Sunny Xia, Zoltán Bozóky, Michelle Di Paola, Onofrio Laselva, Saumel Ahmadi, Daniela Rotin

Cells· December 2021

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Split Chloramphenicol Acetyl-Transferase Assay Reveals Self-Ubiquitylation-Dependent Regulation of UBE3B.
Olga Levin-Kravets, Alina Kordonsky, Anna Shusterman, Sagnik Biswas, Avinash Persaud, Daniela Rotin

J Mol Biol· November 2021

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Function and Regulation of the Epithelial Na Channel ENaC.
Daniela Rotin, Olivier Staub

Compr Physiol· June 2021

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Inhibition of eEF2K synergizes with glutaminase inhibitors or 4EBP1 depletion to suppress growth of triple-negative breast cancer cells.
YoungJun Ju, Yaacov Ben-David, Daniela Rotin, Eldad Zacksenhaus

Sci Rep· April 2021

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Phosphorylation of the Chaperone-Like HspB5 Rescues Trafficking and Function of F508del-CFTR.
Fanny Degrugillier, Abdel Aissat, Virginie Prulière-Escabasse, Lucie Bizard, Benjamin Simonneau, Daniela Rotin

Int J Mol Sci· July 2020

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Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.
Julia Duerr, Dominik H W Leitz, Magdalena Szczygiel, Dmytro Dvornikov, Simon G Fraumann, Daniela Rotin

Nat Commun· April 2020

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The Ion Transporter NKCC1 Links Cell Volume to Cell Mass Regulation by Suppressing mTORC1.
Wael L Demian, Avinash Persaud, Chong Jiang, Étienne Coyaud, Shixuan Liu, Daniela Rotin

Cell Rep· May 2019

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Regulation of SH3PX1 by dNedd4-long at the neuromuscular junction.
Samantha S Wasserman, Alina Shteiman-Kotler, Kathryn Harris, Konstantin G Iliadi, Avinash Persaud, Daniela Rotin

J Biol Chem· February 2019

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Dynamin inhibitors block activation of mTORC1 by amino acids independently of dynamin.
Avinash Persaud, Yann Cormerais, Jacques Pouyssegur, Daniela Rotin

J Cell Sci· January 2018

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Inhaled ENaC antisense oligonucleotide ameliorates cystic fibrosis-like lung disease in mice.
Jeff R Crosby, Chenguang Zhao, Chong Jiang, Dong Bai, Melanie Katz, Daniela Rotin

J Cyst Fibros· November 2017

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Ubiquitylation-dependent oligomerization regulates activity of Nedd4 ligases.
Ilan Attali, William Sam Tobelaim, Avinash Persaud, Khatereh Motamedchaboki, Kobi J Simpson-Lavy, Daniela Rotin

EMBO J· February 2017

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The Ubiquitin Ligase Nedd4L Regulates the Na/K/2Cl Co-transporter NKCC1/SLC12A2 in the Colon.
Chong Jiang, Hiroshi Kawabe, Daniela Rotin

J Biol Chem· February 2017

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System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Wei Zhang, Kuen-Phon Wu, Maria A Sartori, Hari B Kamadurai, Alban Ordureau, Daniela Rotin

Mol Cell· April 2016

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Drosophila Nedd4-long reduces Amphiphysin levels in muscles and leads to impaired T-tubule formation.
Frozan Safi, Alina Shteiman-Kotler, Yunan Zhong, Konstantin G Iliadi, Gabrielle L Boulianne, Daniela Rotin

Mol Biol Cell· March 2016

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RNA Interference Screen to Identify Kinases That Suppress Rescue of ΔF508-CFTR.
Agata M Trzcińska-Daneluti, Anthony Chen, Leo Nguyen, Ryan Murchie, Chong Jiang, Daniela Rotin

Mol Cell Proteomics· June 2015

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LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation.
Ruth Milkereit, Avinash Persaud, Liviu Vanoaica, Adriano Guetg, Francois Verrey, Daniela Rotin

Nat Commun· May 2015

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Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress.
Nancy N Fang, Gerard T Chan, Mang Zhu, Sophie A Comyn, Avinash Persaud, Daniela Rotin

Nat Cell Biol· December 2014

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Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity.
Avinash Persaud, Philipp Alberts, Sara Mari, Jiefei Tong, Ryan Murchie, Daniela Rotin

Sci Signal· October 2014

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