Publications by authors named "Danilo Perrotti"

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Correction: Cytoplasmic DROSHA and non-canonical mechanisms of MiR-155 biogenesis in FLT3-ITD acute myeloid leukemia.
Le Xuan Truong Nguyen, Bin Zhang, Dinh Hoa Hoang, Dandan Zhao, Huafeng Wang, Danilo Perrotti

Leukemia· July 2025

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Acquired miR-142 deficit in leukemic stem cells suffices to drive chronic myeloid leukemia into blast crisis.
Bin Zhang, Dandan Zhao, Fang Chen, David Frankhouser, Huafeng Wang, Danilo Perrotti

Nat Commun· September 2023

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Retraction Notice to: Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development.
Flavia Pichiorri, Sung-Suk Suh, Alberto Rocci, Luciana De Luca, Cristian Taccioli, Danilo Perrotti

Cancer Cell· November 2022

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Retraction Notice to: Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development.
Flavia Pichiorri, Sung-Suk Suh, Alberto Rocci, Luciana De Luca, Cristian Taccioli, Danilo Perrotti

Cancer Cell· November 2022

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Spred1 deficit promotes treatment resistance and transformation of chronic phase CML.
Junjing Qiao, Chen Liang, Dandan Zhao, Le Xuan Truong Nguyen, Fang Chen, Danilo Perrotti

Leukemia· February 2022

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Cytoplasmic DROSHA and non-canonical mechanisms of MiR-155 biogenesis in FLT3-ITD acute myeloid leukemia.
Le Xuan Truong Nguyen, Bin Zhang, Dinh Hoa Hoang, Dandan Zhao, Huafeng Wang, Danilo Perrotti

Leukemia· August 2021

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Treatment-induced arteriolar revascularization and miR-126 enhancement in bone marrow niche protect leukemic stem cells in AML.
Bin Zhang, Le Xuan Truong Nguyen, Dandan Zhao, David E Frankhouser, Huafeng Wang, Danilo Perrotti

J Hematol Oncol· August 2021

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PP2A-activating Drugs Enhance FLT3 Inhibitor Efficacy through AKT Inhibition-Dependent GSK-3β-Mediated c-Myc and Pim-1 Proteasomal Degradation.
Mario Scarpa, Prerna Singh, Christopher M Bailey, Jonelle K Lee, Shivani Kapoor, Danilo Perrotti

Mol Cancer Ther· April 2021

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Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on Antiproliferative and PP2A-Activating Functions.
Giovannino Silvestri, Rossana Trotta, Lorenzo Stramucci, Justin J Ellis, Jason G Harb, Danilo Perrotti

Blood Cancer Discov· July 2020

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Somatic variants in epigenetic modifiers can predict failure of response to imatinib but not to second-generation tyrosine kinase inhibitors.
Georgios Nteliopoulos, Alexandra Bazeos, Simone Claudiani, Gareth Gerrard, Edward Curry, Danilo Perrotti

Haematologica· December 2019

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Comment on "PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL human leukemia".
Danilo Perrotti, Anupriya Agarwal, Claire M Lucas, Goutham Narla, Paolo Neviani

Sci Transl Med· July 2019

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BCR-ABL1 mediated miR-150 downregulation through MYC contributed to myeloid differentiation block and drug resistance in chronic myeloid leukemia.
Klara Srutova, Nikola Curik, Pavel Burda, Filipp Savvulidi, Giovannino Silvestri, Danilo Perrotti

Haematologica· December 2018

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Precision immunotherapy, mutational landscape, and emerging tools to optimize clinical outcomes in patients with classical myeloproliferative neoplasms.
Tariq I Mughal, Thomas Lion, Omar Abdel-Wahab, Ruben Mesa, Robyn M Scherber, Danilo Perrotti

Hematol Oncol· December 2018

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Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
Bin Zhang, Le Xuan Truong Nguyen, Ling Li, Dandan Zhao, Bijender Kumar, Danilo Perrotti

Nat Med· May 2018

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Concurrent Inhibition of Pim and FLT3 Kinases Enhances Apoptosis of FLT3-ITD Acute Myeloid Leukemia Cells through Increased Mcl-1 Proteasomal Degradation.
Shivani Kapoor, Karthika Natarajan, Patrick R Baldwin, Kshama A Doshi, Rena G Lapidus, Danilo Perrotti

Clin Cancer Res· January 2018

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Cellular and Molecular Networks in Chronic Myeloid Leukemia: The Leukemic Stem, Progenitor and Stromal Cell Interplay.
Danilo Perrotti, Giovannino Silvestri, Lorenzo Stramucci, Justine Yu, Rossana Trotta

Curr Drug Targets· September 2017

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Twisting IL-1 signaling to kill CML stem cells.
Lorenzo Stramucci, Danilo Perrotti

Blood· December 2016

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Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia.
Xiaomeng Huang, Sebastian Schwind, Ramasamy Santhanam, Ann-Kathrin Eisfeld, Chi-Ling Chiang, Danilo Perrotti

Oncotarget· September 2016

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Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia.
Kamilla M E Laidlaw, Samuel Berhan, Suhu Liu, Giovannino Silvestri, Tessa L Holyoake, Danilo Perrotti

Oncotarget· August 2016

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RETRACTED: Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development.
Flavia Pichiorri, Sung-Suk Suh, Alberto Rocci, Luciana De Luca, Cristian Taccioli, Danilo Perrotti

Cancer Cell· August 2016

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Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress.
Kshama A Doshi, Rossana Trotta, Karthika Natarajan, Feyruz V Rassool, Adriana E Tron, Danilo Perrotti

Oncotarget· July 2016

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c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase-Activated Leukemias.
Nidal Muvarak, Shannon Kelley, Carine Robert, Maria R Baer, Danilo Perrotti

Mol Cancer Res· April 2015

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From the Biology of PP2A to the PADs for Therapy of Hematologic Malignancies.
Maria Ciccone, George A Calin, Danilo Perrotti

Front Oncol· March 2015

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A "RANning" leap with "XPOrt" into TKI resistance.
Feyruz Rassool, Danilo Perrotti

Blood· March 2015

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Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway.
Ann-Kathrin Eisfeld, Sebastian Schwind, Ravi Patel, Xiaomeng Huang, Ramasamy Santhanam, Danilo Perrotti

Sci Signal· April 2014

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