Publications by authors named "Danish Sayed"

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Constitutive expression of cardiomyocyte Klf9 precipitates metabolic dysfunction and spontaneous cardiomyopathy.
Chandni Thakkar, Saleena Alikunju, Aishwarya Venkatasubramanian, Dorothy D'Mello, Hussain Abbas, Nazish Sayed, Danish Sayed

Cell Signal· December 2025

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Multiscale profiling of tyrosine kinase inhibitor cardiotoxicity reveals mechanosensitive ion channel PIEZO1 as cardioprotective.
Amit Manhas, Yu Liu, Chikage Noishiki, David Wu, Dipti Tripathi, Danish Sayed, Nazish Sayed

Sci Transl Med· December 2025

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The Whsc2/NelfA -dependent transcription complex is required for postnatal cardiac development and heart function.
Saleena Alikunju, Chandni Thakkar, Aishwarya Venkatasubramanian, Zhi Yang, Andreas Ivessa, Danish Sayed

bioRxiv· October 2025

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Constitutive expression of cardiomyocyte Klf9 precipitates metabolic dysfunction and spontaneous heart failure.
Chandni Thakkar, Saleena Alikunju, Aishwarya Venkatasubramanium, Zhi Yang, Nazish Sayed, Danish Sayed

bioRxiv· January 2025

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Reducing branched-chain amino acids improves cardiac stress response in mice by decreasing histone H3K23 propionylation.
Zhi Yang, Minzhen He, Julianne Austin, Danish Sayed, Maha Abdellatif

J Clin Invest· November 2023

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Klf9 plays a critical role in GR -dependent metabolic adaptations in cardiomyocytes.
Chandni Thakkar, Saleena Alikunju, Nandita Niranjan, Wajiha Rizvi, Ali Abbas, Danish Sayed

Cell Signal· November 2023

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G3bp1 - microRNA-1 axis regulates cardiomyocyte hypertrophy.
Saleena Alikunju, Nandita Niranjan, Maha Mohsin, Nazish Sayed, Danish Sayed

Cell Signal· March 2022

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A protocol for transdifferentiation of human cardiac fibroblasts into endothelial cells via activation of innate immunity.
Chun Liu, Pedro Medina, Dilip Thomas, Ian Y Chen, Karim Sallam, Danish Sayed, Nazish Sayed

STAR Protoc· June 2021

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Acute NelfA knockdown restricts compensatory gene expression and precipitates ventricular dysfunction during cardiac hypertrophy.
Saleena Alikunju, Elena Severinova, Zhi Yang, Andreas Ivessa, Danish Sayed

J Mol Cell Cardiol· May 2020

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HIF1α Regulates Early Metabolic Changes due to Activation of Innate Immunity in Nuclear Reprogramming.
Chun Liu, Hongyue Ruan, Farhan Himmati, Ming-Tao Zhao, Christopher C Chen, Danish Sayed, Nazish Sayed

Stem Cell Reports· February 2020

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Oxoglutarate dehydrogenase and acetyl-CoA acyltransferase 2 selectively associate with H2A.Z-occupied promoters and are required for histone modifications.
Sujung Choi, Jessica Pfleger, Yong Heui Jeon, Zhi Yang, Minzhen He, Danish Sayed

Biochim Biophys Acta Gene Regul Mech· October 2019

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Recruitment of RNA Polymerase II to Metabolic Gene Promoters Is Inhibited in the Failing Heart Possibly Through PGC-1α (Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α) Dysregulation.
Santosh Bhat, Adave Chin, Akihiro Shirakabe, Yoshiyuki Ikeda, Shohei Ikeda, Danish Sayed

Circ Heart Fail· March 2019

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Glucocorticoid Receptor-Binding and Transcriptome Signature in Cardiomyocytes.
Elena Severinova, Saleena Alikunju, Wei Deng, Puneet Dhawan, Nazish Sayed, Danish Sayed

J Am Heart Assoc· March 2019

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Transcriptional regulation mediated by H2A.Z via ANP32e-dependent inhibition of protein phosphatase 2A.
Hyewon Shin, Minzhen He, Zhi Yang, Yong Heui Jeon, Jessica Pfleger, Danish Sayed

Biochim Biophys Acta Gene Regul Mech· May 2018

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GTPase Activating Protein (Sh3 Domain) Binding Protein 1 Regulates the Processing of MicroRNA-1 during Cardiac Hypertrophy.
Minzhen He, Zhi Yang, Maha Abdellatif, Danish Sayed

PLoS One· June 2016

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miR-206 Mediates YAP-Induced Cardiac Hypertrophy and Survival.
Yanfei Yang, Dominic P Del Re, Noritsugu Nakano, Sebastiano Sciarretta, Peiyong Zhai, Danish Sayed

Circ Res· October 2015

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Acute targeting of general transcription factor IIB restricts cardiac hypertrophy via selective inhibition of gene transcription.
Danish Sayed, Zhi Yang, Minzhen He, Jessica M Pfleger, Maha Abdellatif

Circ Heart Fail· January 2015

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Transcriptional regulation patterns revealed by high resolution chromatin immunoprecipitation during cardiac hypertrophy.
Danish Sayed, Minzhen He, Zhi Yang, Lin Lin, Maha Abdellatif

J Biol Chem· January 2013

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GATA4 expression is primarily regulated via a miR-26b-dependent post-transcriptional mechanism during cardiac hypertrophy.
Mingyue Han, Zhi Yang, Danish Sayed, Minzhen He, Shumin Gao

Cardiovasc Res· March 2012

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MicroRNAs in development and disease.
Danish Sayed, Maha Abdellatif

Physiol Rev· July 2011

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AKT-ing via microRNA.
Danish Sayed, Maha Abdellatif

Cell Cycle· August 2010

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An antagonism between the AKT and beta-adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5p.
Shweta Rane, Minzhen He, Danish Sayed, Lin Yan, Dorothy Vatner

Cell Signal· July 2010

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MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand.
Danish Sayed, Minzhen He, Chull Hong, Shumin Gao, Shweta Rane

J Biol Chem· June 2010

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Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes.
Shweta Rane, Minzhen He, Danish Sayed, Himanshu Vashistha, Ashwani Malhotra

Circ Res· April 2009

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MicroRNAs challenge the status quo of therapeutic targeting.
Danish Sayed, Shweta Rane, Maha Abdellatif

J Cardiovasc Transl Res· March 2009

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