Publications by authors named "Danny D Sahtoe"

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Design of facilitated dissociation enables timing of cytokine signalling.
Adam J Broerman, Christoph Pollmann, Yang Zhao, Mauriz A Lichtenstein, Mark D Jackson, Danny D Sahtoe

Nature· November 2025

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Neurodegeneration emerges at a cellular tipping point between aggregate accumulation and removal.
Matthew W Cotton, Shriram Venkatesan, Joseph S Beckwith, Dorothea Böken, Catherine K Xu, Danny D Sahtoe

bioRxiv· October 2025

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Designed endocytosis-inducing proteins degrade targets and amplify signals.
Buwei Huang, Mohamad Abedi, Green Ahn, Brian Coventry, Isaac Sappington, Danny D Sahtoe

Nature· February 2025

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Design of facilitated dissociation enables control over cytokine signaling duration.
Adam J Broerman, Christoph Pollmann, Mauriz A Lichtenstein, Mark D Jackson, Maxx H Tessmer, Danny D Sahtoe

bioRxiv· November 2024

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Design of amyloidogenic peptide traps.
Danny D Sahtoe, Ewa A Andrzejewska, Hannah L Han, Enrico Rennella, Matthias M Schneider

Nat Chem Biol· August 2024

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De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity.
Rubul Mout, Ross C Bretherton, Justin Decarreau, Sangmin Lee, Nicole Gregorio, Danny D Sahtoe

Proc Natl Acad Sci U S A· February 2024

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De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity.
Rubul Mout, Ross C Bretherton, Justin Decarreau, Sangmin Lee, Natasha I Edman, Danny D Sahtoe

bioRxiv· June 2023

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Exploiting conformational dynamics to modulate the function of designed proteins.
Enrico Rennella, Danny D Sahtoe, David Baker, Lewis E Kay

Proc Natl Acad Sci U S A· May 2023

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Reconfigurable asymmetric protein assemblies through implicit negative design.
Danny D Sahtoe, Florian Praetorius, Alexis Courbet, Yang Hsia, Basile I M Wicky

Science· January 2022

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Generation of ordered protein assemblies using rigid three-body fusion.
Ivan Vulovic, Qing Yao, Young-Jun Park, Alexis Courbet, Andrew Norris, Danny D Sahtoe

Proc Natl Acad Sci U S A· June 2021

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Transferrin receptor targeting by de novo sheet extension.
Danny D Sahtoe, Adrian Coscia, Nur Mustafaoglu, Lauren M Miller, Daniel Olal

Proc Natl Acad Sci U S A· April 2021

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BAP1/ASXL1 recruitment and activation for H2A deubiquitination.
Danny D Sahtoe, Willem J van Dijk, Reggy Ekkebus, Huib Ovaa, Titia K Sixma

Nat Commun· January 2016

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The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A.
Francesca Mattiroli, Michael Uckelmann, Danny D Sahtoe, Willem J van Dijk, Titia K Sixma

Nat Commun· November 2015

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Layers of DUB regulation.
Danny D Sahtoe, Titia K Sixma

Trends Biochem Sci· August 2015

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Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G.
Danny D Sahtoe, Willem J van Dijk, Farid El Oualid, Reggy Ekkebus, Huib Ovaa

Mol Cell· March 2015

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Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases.
Mark P A Luna-Vargas, Evangelos Christodoulou, Andrea Alfieri, Willem J van Dijk, Magda Stadnik, Danny D Sahtoe

J Struct Biol· August 2011

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