Publications by authors named "Danny Wangsa"

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EGFR amplification and PI3K pathway mutations identify a subset of breast cancers that synergistically respond to EGFR and PI3K inhibition.
David J Wisniewski, Donna Voeller, Yonit A Addissie, Sachin Kumar Deshmukh, Sharon Wu, Darawalee Wangsa, Danny Wangsa

Oncogene· January 2026

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EGFR amplification and PI3K pathway mutations identify a subset of breast cancers that synergistically respond to EGFR and PI3K inhibition.
David J Wisniewski, Donna Voeller, Yonit A Addissie, Sachin Kumar Deshmukh, Sharon Wu, Darawalee Wangsa, Danny Wangsa

bioRxiv· September 2025

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High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma.
Martin Lang, Laura S Schmidt, Kelli M Wilson, Christopher J Ricketts, Carole Sourbier, Darawalee Wangsa, Danny Wangsa

J Exp Clin Cancer Res· April 2023

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Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies.
Sushant Patkar, Kerstin Heselmeyer-Haddad, Noam Auslander, Daniela Hirsch, Jordi Camps, Darawalee Wangsa, Danny Wangsa

Genome Med· May 2021

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Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments.
Darmood Wei, Youfeng Yang, Christopher J Ricketts, Cathy D Vocke, Mark W Ball, Darawalee Wangsa, Danny Wangsa

Genes Chromosomes Cancer· August 2020

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Single-Cell-Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response.
Rüdiger Braun, Lena Anthuber, Daniela Hirsch, Darawalee Wangsa, Justin Lack, Danny Wangsa

Clin Cancer Res· July 2020

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Bile acid-induced "Minority MOMP" promotes esophageal carcinogenesis while maintaining apoptotic resistance via Mcl-1.
Yuan Xu, Deborah R Surman, Laurence Diggs, Sichuan Xi, Shaojian Gao, Danny Wangsa, Darawalee Wangsa

Oncogene· January 2020

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Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression.
Rüdiger Braun, Scott Ronquist, Darawalee Wangsa, Haiming Chen, Lena Anthuber, Danny Wangsa

Neoplasia· April 2019

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Sex-chromosome dosage effects on gene expression in humans.
Armin Raznahan, Neelroop N Parikshak, Vijay Chandran, Jonathan D Blumenthal, Liv S Clasen, Danny Wangsa

Proc Natl Acad Sci U S A· July 2018

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ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer.
Vivek Shukla, Mahadev Rao, Hongen Zhang, Jeanette Beers, Darawalee Wangsa, Danny Wangsa

Cancer Res· November 2017

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A multiplex preclinical model for adenoid cystic carcinoma of the salivary gland identifies regorafenib as a potential therapeutic drug.
Chen Chen, Sujata Choudhury, Darawalee Wangsa, Chamille J Lescott, Devan J Wilkins, Danny Wangsa

Sci Rep· September 2017

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HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes.
Hang Yuan, Ewa Krawczyk, Jan Blancato, Christopher Albanese, Dan Zhou, Danny Wangsa

Sci Rep· April 2017

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Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.
Yuwei Zhang, Rodrigo Calado, Mahadev Rao, Julie A Hong, Alan K Meeker, Danny Wangsa

PLoS One· November 2015

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A ten-year retrospective analysis of the distribution, use and phenotypic characteristics of the LAD2 human mast cell line.
Arnold S Kirshenbaum, Amy Petrik, Rosemary Walsh, Tara L Kirby, Sury Vepa, Danny Wangsa

Int Arch Allergy Immunol· December 2014

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Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability.
Keiko Akagi, Jingfeng Li, Tatevik R Broutian, Hesed Padilla-Nash, Weihong Xiao, Danny Wangsa

Genome Res· February 2014

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CKAP2 ensures chromosomal stability by maintaining the integrity of microtubule nucleation sites.
Chanelle M Case, Dan L Sackett, Danny Wangsa, Tatiana Karpova, James G McNally

PLoS One· January 2014

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Aneuploidy, oncogene amplification and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells.
Hesed M Padilla-Nash, Nicole E McNeil, Ming Yi, Quang-Tri Nguyen, Yue Hu, Danny Wangsa

Carcinogenesis· August 2013

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Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs.
Thomas Winkler, So Gun Hong, Jake E Decker, Mary J Morgan, Chuanfeng Wu, Danny Wangsa

J Clin Invest· May 2013

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Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances.
Hesed M Padilla-Nash, Karen Hathcock, Nicole E McNeil, David Mack, Daniel Hoeppner, Danny Wangsa

Genes Chromosomes Cancer· April 2012

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Genomic instability influences the transcriptome and proteome in endometrial cancer subtypes.
Jens K Habermann, Nana K Bündgen, Timo Gemoll, Sampsa Hautaniemi, Caroline Lundgren, Danny Wangsa

Mol Cancer· October 2011

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Genome and transcriptome profiles of CD133-positive colorectal cancer cells.
Timo Gaiser, Jordi Camps, Sandra Meinhardt, Danny Wangsa, Quang Tri Nguyen

Am J Pathol· April 2011

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Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines.
Turid Knutsen, Hesed M Padilla-Nash, Danny Wangsa, Linda Barenboim-Stapleton, Jordi Camps

Genes Chromosomes Cancer· March 2010

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Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer.
Jordi Camps, Quang Tri Nguyen, Hesed M Padilla-Nash, Turid Knutsen, Nicole E McNeil, Danny Wangsa

Genes Chromosomes Cancer· November 2009

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Chromosomal copy number changes of locally advanced rectal cancers treated with preoperative chemoradiotherapy.
Marian Grade, Jochen Gaedcke, Danny Wangsa, Sudhir Varma, Jaje Beckmann

Cancer Genet Cytogenet· August 2009

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Cisplatin depletes TREX2 and causes Robertsonian translocations as seen in TREX2 knockout cells.
Ming-Jiu Chen, Lavinia C Dumitrache, Danny Wangsa, Sheng-Mei Ma, Hesed Padilla-Nash

Cancer Res· October 2007

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