Publications by authors named "Dao-Hong Lin"

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Mechanistic target of rapamycin complex-2 (mTORc2) mediates the effect of over-night high K on Kir4.1/Kir4.1 in the DCT and ENaC/ROMK in ASDN.
Xin-Peng Duan, Jun-Ya Zheng, Chengbiao Zhang, Shafiq Alam, Wen-Hui Wang, Dao-Hong Lin

Am J Physiol Renal Physiol· November 2025

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Mechanistic Target of Rapamycin Complex 1 in Distal Convoluted Tubule and Renal Potassium Handling.
Yu Xiao, Xin-Peng Duan, Cheng-Biao Zhang, Wen-Hui Wang, Dao-Hong Lin

J Am Soc Nephrol· October 2025

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Kir4.1/Kir5.1 of distal convoluted tubule is required for short-term angiotensin-II-induced stimulation of Na-Cl cotransporter.
Xin-Peng Duan, Xin-Xin Meng, Yu Xiao, Cheng-Biao Zhang, Ruimin Gu, Dao-Hong Lin

Am J Physiol Renal Physiol· June 2025

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Kir5.1 regulates Kir4.2 expression and is a key component of the 50-pS inwardly rectifying potassium channel in basolateral membrane of mouse proximal tubules.
Cheng-Biao Zhang, Zheng Ding, Xin-Peng Duan, Tanzina Chowdhury, Wen-Hui Wang, Dao-Hong Lin

Am J Physiol Renal Physiol· February 2025

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Angiotensin II-Type-1a Receptor and Renal K + Wasting during Overnight Low-Na + Intake.
Xin-Peng Duan, Jun-Ya Zheng, Yu Xiao, Cheng-Biao Zhang, Dao-Hong Lin

J Am Soc Nephrol· November 2024

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mTORc2 in Distal Convoluted Tubule and Renal K + Excretion during High Dietary K + Intake.
Xin-Peng Duan, Jun-Ya Zheng, Shao-Peng Jiang, Ming-Xiao Wang, Chengbiao Zhang, Dao-Hong Lin

J Am Soc Nephrol· September 2024

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Role of calcineurin in regulating renal potassium (K) excretion: Mechanisms of calcineurin inhibitor-induced hyperkalemia.
Xin-Peng Duan, Cheng-Biao Zhang, Wen-Hui Wang, Dao-Hong Lin

Acta Physiol (Oxf)· August 2024

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Role of Kir4.1/Kir5.1 in mediating Angiotensin-II (Ang-II)-induced stimulation of thiazide-sensitive Na-Cl cotransporter.
Xin-Peng Duan, Xin-Xin Meng, Yu Xiao, Cheng-Biao Zhang, Ruimin Gu, Dao-Hong Lin

bioRxiv· July 2024

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Role of Angiotensin II Type 1a Receptor (AT1aR) of Renal Tubules in Regulating Inwardly Rectifying Potassium Channels 4.2 (Kir4.2), Kir4.1, and Epithelial Na Channel (ENaC).
Xin-Peng Duan, Yu Xiao, Xiao-Tong Su, Jun-Ya Zheng, Susan Gurley, Jacqueline Emathinger, Chao-Ling Yang, Dao-Hong Lin

Hypertension· January 2024

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Calcineurin inhibitors stimulate Kir4.1/Kir5.1 of the distal convoluted tubule to increase NaCl cotransporter.
Dan-Dan Zhang, Xin-Peng Duan, Kerim Mutig, Franziska Rausch, Yu Xiao, Dao-Hong Lin

JCI Insight· April 2023

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Multiple molecular mechanisms are involved in the activation of the kidney sodium-chloride cotransporter by hypokalemia.
Adrián R Murillo-de-Ozores, Héctor Carbajal-Contreras, Germán R Magaña-Ávila, Raquel Valdés, Leoneli I Grajeda-Medina, Dao-Hong Lin

Kidney Int· November 2022

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Role of inwardly rectifying K+ channel 5.1 (Kir5.1) in the regulation of renal membrane transport.
Dao-Hong Lin, Xin-Peng Duan, Jun-Ya Zheng, Wen-Hui Wang

Curr Opin Nephrol Hypertens· September 2022

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Inwardly rectifying K channels 4.1 and 5.1 (Kir4.1/Kir5.1) in the renal distal nephron.
Wen-Hui Wang, Dao-Hong Lin

Am J Physiol Cell Physiol· August 2022

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ROMK channels are inhibited in the aldosterone-sensitive distal nephron of renal tubule Nedd4-2-deficient mice.
Dan-Dan Zhang, Jun-Ya Zheng, Xin-Peng Duan, Dao-Hong Lin, Wen-Hui Wang

Am J Physiol Renal Physiol· January 2022

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Deletion of renal Nedd4-2 abolishes the effect of high K intake on Kir4.1/Kir5.1 and NCC activity in the distal convoluted tubule.
Yu Xiao, Xin-Peng Duan, Dan-Dan Zhang, Wen-Hui Wang, Dao-Hong Lin

Am J Physiol Renal Physiol· July 2021

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Deletion of Kir5.1 abolishes the effect of high Na intake on Kir4.1 and Na-Cl cotransporter.
Xin-Peng Duan, Peng Wu, Dan-Dan Zhang, Zhong-Xiuzi Gao, Yu Xiao, Dao-Hong Lin

Am J Physiol Renal Physiol· June 2021

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Deletion of renal Nedd4-2 abolishes the effect of high sodium intake (HS) on Kir4.1, ENaC, and NCC and causes hypokalemia during high HS.
Dan-Dan Zhang, Xin-Peng Duan, Yu Xiao, Peng Wu, Zhong-Xiuzi Gao, Dao-Hong Lin

Am J Physiol Renal Physiol· May 2021

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Renal Tubule Nedd4-2 Deficiency Stimulates Kir4.1/Kir5.1 and Thiazide-Sensitive NaCl Cotransporter in Distal Convoluted Tubule.
Peng Wu, Xiao-Tong Su, Zhong-Xiuzi Gao, Dan-Dan Zhang, Xin-Peng Duan, Dao-Hong Lin

J Am Soc Nephrol· June 2020

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Effect of Angiotensin II on ENaC in the Distal Convoluted Tubule and in the Cortical Collecting Duct of Mineralocorticoid Receptor Deficient Mice.
Peng Wu, Zhong-Xiuzi Gao, Dan-Dan Zhang, Xin-Peng Duan, Andrew S Terker, Dao-Hong Lin

J Am Heart Assoc· April 2020

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Inhibition of AT2R and Bradykinin Type II Receptor (BK2R) Compromises High K Intake-Induced Renal K Excretion.
Li Gu, JunLin Wang, Dan-Dan Zhang, XinXin Meng, YunHong Zhang, Dao-Hong Lin

Hypertension· February 2020

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Mg restriction downregulates NCC through NEDD4-2 and prevents its activation by hypokalemia.
Mohammed Z Ferdaus, Anindit Mukherjee, Jonathan W Nelson, Philip J Blatt, Lauren N Miller, Dao-Hong Lin

Am J Physiol Renal Physiol· October 2019

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Deletion of Kir5.1 Impairs Renal Ability to Excrete Potassium during Increased Dietary Potassium Intake.
Peng Wu, Zhong-Xiuzi Gao, Dan-Dan Zhang, Xiao-Tong Su, Wen-Hui Wang, Dao-Hong Lin

J Am Soc Nephrol· August 2019

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Kir4.1/Kir5.1 Activity Is Essential for Dietary Sodium Intake-Induced Modulation of Na-Cl Cotransporter.
Peng Wu, Zhong-Xiuzi Gao, Xiao-Tong Su, Ming-Xiao Wang, Wen-Hui Wang, Dao-Hong Lin

J Am Soc Nephrol· February 2019

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Norepinephrine-Induced Stimulation of Kir4.1/Kir5.1 Is Required for the Activation of NaCl Transporter in Distal Convoluted Tubule.
Xin-Peng Duan, Li Gu, Yu Xiao, Zhong-Xiuzi Gao, Peng Wu, Jun-Lin Wang, Dao-Hong Lin

Hypertension· January 2019

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Bradykinin Stimulates Renal Na and K Excretion by Inhibiting the K Channel (Kir4.1) in the Distal Convoluted Tubule.
Dan-Dan Zhang, Zhong-Xiuzi Gao, Carlos P Vio, Yu Xiao, Peng Wu, Jun-Lin Wang, Dao-Hong Lin

Hypertension· August 2018

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