Publications by authors named "Darin Clark"

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Exercise mitigates high-fat diet-induced cardiac dysfunction via APOE genotype- and immune-dependent mechanisms: A photon-counting CT study in adult mice.
Rohan Nadkarni, Alex J Allphin, Darin P Clark, Yi Qi, Zay Yar Han

PLoS One· December 2025

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Photon-Counting Micro-CT for Bone Morphometry in Murine Models.
Rohan Nadkarni, Zay Yar Han, Alex J Allphin, Darin P Clark, Alexandra Badea

Tomography· November 2025

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An end-to-end CT simulation framework with graphical user interface and sample scanner models.
Amar Kavuri, Milo Fryling, Nicholas Felice, Lior Malvin, Darin P Clark

Med Phys· October 2025

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Photon-counting micro-CT scanner for deep learning-enabled small animal perfusion imaging.
Alex J Allphin, Rohan Nadkarni, Darin P Clark, Cristian T Badea

Phys Med Biol· July 2025

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Denoising pediatric cardiac photon-counting CT data with sparse coding and data-adaptive, self-supervised deep learning.
Darin P Clark, Joseph Y Cao, Cristian T Badea

Med Phys· July 2025

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AAPM Truth-based CT (TrueCT) reconstruction grand challenge.
Ehsan Abadi, W Paul Segars, Nicholas Felice, Saman Sotoudeh-Paima, Eric A Hoffman, Darin Clark

Med Phys· April 2025

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Assessing the cardioprotective effects of exercise in APOE mouse models using deep learning and photon-counting micro-CT.
Alex J Allphin, Rohan Nadkarni, Zay Y Han, Darin P Clark, Ketan B Ghaghada

PLoS One· April 2025

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Black-box Optimization of CT Acquisition and Reconstruction Parameters: A Reinforcement Learning Approach.
David Fenwick, Navid NaderiAlizadeh, Vahid Tarokh, Darin Clark, Jayasai Rajagopal

Proc SPIE Int Soc Opt Eng· February 2025

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Investigating deep learning strategies for fast denoising of 5D cardiac photon-counting micro-CT images.
Rohan Nadkarni, Darin P Clark, Alex Jeffrey Allphin, Cristian T Badea

Phys Med Biol· September 2024

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High-resolution hybrid micro-CT imaging pipeline for mouse brain region segmentation and volumetric morphometry.
Rohan Nadkarni, Zay Yar Han, Robert J Anderson, Alex J Allphin, Darin P Clark

PLoS One· May 2024

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Multivariate investigation of aging in mouse models expressing the Alzheimer's protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics.
Hae Sol Moon, Ali Mahzarnia, Jacques Stout, Robert J Anderson, Madison Strain, Darin Clark

Brain Struct Funct· January 2024

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Evaluation of the impact of a novel denoising algorithm on image quality in dual-energy abdominal CT of obese patients.
Fides R Schwartz, Darin P Clark, Francesca Rigiroli, Kevin Kalisz, Benjamin Wildman-Tobriner

Eur Radiol· October 2023

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Advanced photon counting CT imaging pipeline for cardiac phenotyping of apolipoprotein E mouse models.
Alex J Allphin, Ali Mahzarnia, Darin P Clark, Yi Qi, Zay Y Han

PLoS One· October 2023

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MCR toolkit: A GPU-based toolkit for multi-channel reconstruction of preclinical and clinical x-ray CT data.
Darin P Clark, Cristian T Badea

Med Phys· August 2023

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A Deep Learning Approach for Rapid and Generalizable Denoising of Photon-Counting Micro-CT Images.
Rohan Nadkarni, Darin P Clark, Alex J Allphin, Cristian T Badea

Tomography· July 2023

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Material decomposition from photon-counting CT using a convolutional neural network and energy-integrating CT training labels.
Rohan Nadkarni, Alex Allphin, Darin P Clark, Cristian T Badea

Phys Med Biol· July 2022

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Photon Counting CT and Radiomic Analysis Enables Differentiation of Tumors Based on Lymphocyte Burden.
Alex J Allphin, Yvonne M Mowery, Kyle J Lafata, Darin P Clark, Alex M Bassil

Tomography· March 2022

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Detection of Lung Nodules in Micro-CT Imaging Using Deep Learning.
Matthew D Holbrook, Darin P Clark, Rutulkumar Patel, Yi Qi, Alex M Bassil

Tomography· August 2021

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Evaluating renal lesions using deep-learning based extension of dual-energy FoV in dual-source CT-A retrospective pilot study.
Fides R Schwartz, Darin P Clark, Yuqin Ding, Juan Carlos Ramirez-Giraldo, Cristian T Badea

Eur J Radiol· June 2021

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Deep learning based spectral extrapolation for dual-source, dual-energy x-ray computed tomography.
Darin P Clark, Fides R Schwartz, Daniele Marin, Juan C Ramirez-Giraldo, Cristian T Badea

Med Phys· September 2020

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Photon-counting cine-cardiac CT in the mouse.
Darin P Clark, Matthew Holbrook, Chang-Lung Lee, Cristian T Badea

PLoS One· March 2020

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Computational 3D histological phenotyping of whole zebrafish by X-ray histotomography.
Yifu Ding, Daniel J Vanselow, Maksim A Yakovlev, Spencer R Katz, Alex Y Lin, Darin P Clark

Elife· May 2019

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Abstracts of Presentations at the Association of Clinical Scientists 139 Meeting Hershey, PA, May 15-18, 2019.
Keri Donaldson, Jeanine M Buchanich, Patricia Sue Grigson, Erin Deneke, Keri Donaldson, Darin P Clark

Ann Clin Lab Sci· May 2019

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Overcoming detector limitations of x-ray photon counting for preclinical microcomputed tomography.
Matthew Holbrook, Darin P Clark, Cristian T Badea

J Med Imaging (Bellingham)· January 2019

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Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography.
Alex Y Lin, Yifu Ding, Daniel J Vanselow, Spencer R Katz, Maksim A Yakovlev, Darin P Clark

J Vis Exp· October 2018

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