Publications by authors named "Darragh B Freir"

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The Familial British Dementia Mutation Promotes Formation of Neurotoxic Cystine Cross-linked Amyloid Bri (ABri) Oligomers.
Adam Cantlon, Carlo Sala Frigerio, Darragh B Freir, Barry Boland, Ming Jin

J Biol Chem· July 2015

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Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity.
Andrew J Nicoll, Silvia Panico, Darragh B Freir, Daniel Wright, Cassandra Terry

Nat Commun· April 2014

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Aβ oligomers inhibit synapse remodelling necessary for memory consolidation.
Darragh B Freir, Rocio Fedriani, Darren Scully, Imelda M Smith, Dennis J Selkoe

Neurobiol Aging· December 2011

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Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites.
Darragh B Freir, Andrew J Nicoll, Igor Klyubin, Silvia Panico, Jessica M Mc Donald

Nat Commun· June 2011

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Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils.
Brian O'Nuallain, Darragh B Freir, Andrew J Nicoll, Emmanuel Risse, Neil Ferguson

J Neurosci· October 2010

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Inhibition of LTP in vivo by beta-amyloid peptide in different conformational states.
Adrien W Schmid, Darragh B Freir, Caroline E Herron

Brain Res· March 2008

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Amyloid beta peptide as a physiological modulator of neuronal 'A'-type K+ current.
Leigh D Plant, Nicola J Webster, John P Boyle, Martin Ramsden, Darragh B Freir

Neurobiol Aging· November 2006

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Inhibition of L-type voltage dependent calcium channels causes impairment of long-term potentiation in the hippocampal CA1 region in vivo.
Darragh B Freir, Caroline E Herron

Brain Res· March 2003

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