Publications by authors named "Darrell Belke"

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Administration of the K channel activator SKA-31 improves long-term endothelial function, blood pressure regulation and cardiac performance in rats with type 2 diabetes.
Ramesh C Mishra, Rayan Khaddaj Mallat, Cini M John, Darrell D Belke, Liam Hamm

Metabolism· January 2026

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Monomethyl fumarate confers cardioprotection after myocardial infarction via HCAR2-dependent activation of PI3K/Akt signaling.
Yifeng Zhang, Yu Gui, Darrell Belke, Xiaopu Wang, Wen Su

Cell Death Discov· December 2025

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Roles of Brd4 in Vascular Smooth Muscle Cells: Implications for Aging and Vascular Dysfunction.
Jiaxing Sun, Yu Gui, Hao Yin, Binjie Yan, Yong-Xiang Chen, Darrell D Belke

Arterioscler Thromb Vasc Biol· July 2025

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Evaluation of the Bioinductive Effects of a Novel Antibiotic Eluting Cardiac Implantable Electronic Device Envelope.
Sun Woo Kim, Nathan W Fedak, Eleanor Love, Alexander Tam, Ali Fatehi Hassanabad, Darrell Belke

J Funct Biomater· June 2025

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Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans.
Bo Sun, Mingke Ni, Yanhui Li, Zhenpeng Song, Hui Wang, Darrell Belke

Circulation· March 2025

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Chronic angiotensin-converting enzyme inhibition attenuates frailty and protects against atrial fibrillation in aging mice.
Hailey J Jansen, Megan D McRae, Darrell D Belke, Robert A Rose

Heart Rhythm· February 2025

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Administration of the K channel activator SKA-31 improves endothelial function in the aorta of atherosclerosis-prone mice.
O Daniel Vera, Ramesh C Mishra, Rayan Khaddaj-Mallat, Liam Hamm, Barak Almarzouq, Darrell D Belke

Front Pharmacol· February 2025

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Targeting endothelial K channels in vivo restores arterial and endothelial function in type 2 diabetic rats.
Ramesh C Mishra, Darrell D Belke, Latika Singh, Heike Wulff, Andrew P Braun

Metabolism· November 2024

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Pericardial Fluid of Patients With Coronary Artery Disease Can Drive Fibrosis Via TGF-Beta Pathway.
Ali Fatehi Hassanabad, Darrell D Belke, Paul M K Gordon, Guoqi Teng, Jameson A Dundas

JACC Basic Transl Sci· November 2024

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Acute pericardial postischemic inflammatory responses: Characterization using a preclinical porcine model.
Ali Fatehi Hassanabad, Jeannine Turnbull, Cheryl Hall, Friederike I Schoettler, Mortaza Fatehi Hassanabad, Darrell D Belke

Cardiovasc Pathol· September 2024

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PDE4D mediates impaired β-adrenergic receptor signalling in the sinoatrial node in mice with hypertensive heart disease.
Tristan W Dorey, Megan D McRae, Darrell D Belke, Robert A Rose

Cardiovasc Res· December 2023

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Pharmacological inhibition of MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) induces ferroptosis in vascular smooth muscle cells.
Binjie Yan, Darrell Belke, Yu Gui, Yong-Xiang Chen, Zhi-Sheng Jiang

Cell Death Discov· December 2023

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Natriuretic Peptide Receptor B Protects Against Atrial Fibrillation by Controlling Atrial cAMP Via Phosphodiesterase 2.
Tristan W Dorey, Yingjie Liu, Hailey J Jansen, Loryn J Bohne, Martin Mackasey, Darrell D Belke

Circ Arrhythm Electrophysiol· November 2023

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Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm.
Anshul S Jadli, Karina P Gomes, Noura N Ballasy, Tishani Methsala Wijesuriya, Darrell Belke

Biosci Rep· November 2023

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Micronized Acellular Matrix Biomaterial Leverages Eosinophils for Postinfarct Cardiac Repair.
Vishnu Vasanthan, Ali Fatehi Hassanabad, Darrell Belke, Guoqi Teng, Carmina Albertine Isidoro

JACC Basic Transl Sci· August 2023

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Glucagon-Like Peptide-1 Protects Against Atrial Fibrillation and Atrial Remodeling in Type 2 Diabetic Mice.
Loryn J Bohne, Hailey J Jansen, Tristan W Dorey, Irene M Daniel, K Lockhart Jamieson, Darrell D Belke

JACC Basic Transl Sci· August 2023

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Increased Ca Transient Underlies RyR2-Related Left Ventricular Noncompaction.
Mingke Ni, Yanhui Li, Jinhong Wei, Zhenpeng Song, Hui Wang, Darrell Belke

Circ Res· July 2023

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Acellular biomaterial modulates myocardial inflammation and promotes endogenous mechanisms of postinfarct cardiac repair.
Vishnu Vasanthan, Hanjoo B Shim, Guoqi Teng, Darrell Belke, Daniyil Svystonyuk

J Thorac Cardiovasc Surg· March 2023

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Polo-like kinase 4 inhibitor CFI-400945 inhibits carotid arterial neointima formation but increases atherosclerosis.
Jiaxing Sun, Darrell Belke, Yu Gui, Yong-Xiang Chen, Shenghua Zhou

Cell Death Discov· February 2023

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Smoothelin-like 1 knockout mice display sex-dependent alterations in blood flow and cardiac function.
Megha Murali, Sara R Turner, Darrell D Belke, William C Cole, Justin A MacDonald

Can J Physiol Pharmacol· January 2023

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RyR2 Serine-2030 PKA Site Governs Ca Release Termination and Ca Alternans.
Jinhong Wei, Wenting Guo, Ruiwu Wang, John Paul Estillore, Darrell Belke

Circ Res· January 2023

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Attenuation of Smooth Muscle Cell Phenotypic Switching by Angiotensin 1-7 Protects against Thoracic Aortic Aneurysm.
Anshul S Jadli, Noura N Ballasy, Karina P Gomes, Cameron D A Mackay, Megan Meechem, Darrell Belke

Int J Mol Sci· December 2022

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Loss of Natriuretic Peptide Receptor C Enhances Sinoatrial Node Dysfunction in Aging and Frail Mice.
Hailey J Jansen, Motahareh Moghtadaei, Sara A Rafferty, Darrell D Belke, Robert A Rose

J Gerontol A Biol Sci Med Sci· May 2022

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Proteomic Analysis Suggests Altered Mitochondrial Metabolic Profile Associated With Diabetic Cardiomyopathy.
Karina P Gomes, Anshul S Jadli, Luiz G N de Almeida, Noura N Ballasy, Pariya Edalat, Darrell Belke

Front Cardiovasc Med· March 2022

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PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Triggers Vascular Smooth Muscle Cell Senescence and Apoptosis: Implication of Its Direct Role in Degenerative Vascular Disease.
Yanan Guo, Zhihan Tang, Binjie Yan, Hao Yin, Shi Tai, Darrell Belke

Arterioscler Thromb Vasc Biol· January 2022

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