Publications by authors named "Darren A Cook"

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Development of Pyrazolopyrimidine Anti- Agents for the Treatment of Filariasis.
Paul McGillan, Neil G Berry, Gemma L Nixon, Suet C Leung, Peter J H Webborn, Darren A Cook

ACS Med Chem Lett· September 2021

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Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner.
Jan-Hendrik Schroeder, David McCarthy, Tadge Szestak, Darren A Cook, Mark J Taylor

PLoS Negl Trop Dis· May 2017

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Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.
Raman Sharma, Ghaith Al Jayoussi, Hayley E Tyrer, Joanne Gamble, Laura Hayward, Darren A N Cook

Sci Rep· March 2016

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Development and validation of a high-throughput anti-Wolbachia whole-cell screen: a route to macrofilaricidal drugs against onchocerciasis and lymphatic filariasis.
Rachel H Clare, Darren A N Cook, Kelly L Johnston, Louise Ford, Stephen A Ward

J Biomol Screen· January 2015

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Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms.
Nicholas R Casewell, Simon C Wagstaff, Wolfgang Wüster, Darren A N Cook, Fiona M S Bolton

Proc Natl Acad Sci U S A· June 2014

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Autophagy regulates Wolbachia populations across diverse symbiotic associations.
Denis Voronin, Darren A N Cook, Andrew Steven, Mark J Taylor

Proc Natl Acad Sci U S A· June 2012

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Research strategies to improve snakebite treatment: challenges and progress.
Robert A Harrison, Darren A Cook, Camila Renjifo, Nicholas R Casewell, Rachel B Currier

J Proteomics· August 2011

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Pre-clinical assays predict pan-African Echis viper efficacy for a species-specific antivenom.
Nicholas R Casewell, Darren A N Cook, Simon C Wagstaff, Abdulsalami Nasidi, Nandul Durfa

PLoS Negl Trop Dis· October 2010

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Analysis of camelid IgG for antivenom development: Serological responses of venom-immunised camels to prepare either monospecific or polyspecific antivenoms for West Africa.
Darren A N Cook, Timothy Owen, Simon C Wagstaff, Joerg Kinne, Ulrich Wernery

Toxicon· September 2010

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Analysis of camelid antibodies for antivenom development: Neutralisation of venom-induced pathology.
Darren A N Cook, Timothy Owen, Simon C Wagstaff, Joerg Kinne, Ulrich Wernery

Toxicon· September 2010

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Analysis of camelid IgG for antivenom development: Immunoreactivity and preclinical neutralisation of venom-induced pathology by IgG subclasses, and the effect of heat treatment.
Darren A N Cook, Chamali L Samarasekara, Simon C Wagstaff, Joerg Kinne, Ulrich Wernery

Toxicon· September 2010

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