Publications by authors named "Darren Fayne"

Claim this Profile
T
The Use of Computational Approaches to Design Nanodelivery Systems.
Abedalrahman Abughalia, Mairead Flynn, Paul F A Clarke, Darren Fayne, Oliviero L Gobbo

Nanomaterials (Basel)· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis, Computational Studies, and Structural Analysis of 1-(3,5-Dimethoxyphenyl)azetidin-2-ones with Antiproliferative Activity in Breast Cancer and Chemoresistant Colon Cancer.
Azizah M Malebari, Shubhangi Kandwal, Abdirahman Ali, Darren Fayne, Brendan Twamley

Pharmaceuticals (Basel)· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction: Wang et al. Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells. 2023, , 1000.
Shu Wang, Azizah M Malebari, Thomas F Greene, Shubhangi Kandwal, Darren Fayne

Pharmaceuticals (Basel)· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction: Malebari et al. Synthesis and Antiproliferative Evaluation of 3-Chloroazetidin-2-ones with Antimitotic Activity: Heterocyclic Bridged Analogues of Combretastatin A-4. 2021, , 1119.
Azizah M Malebari, Shu Wang, Thomas F Greene, Niamh M O'Boyle, Darren Fayne

Pharmaceuticals (Basel)· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13.
Oleksandra Herasymenko, Madhushika Silva, Abd Al-Aziz A Abu-Saleh, Ayaz Ahmad, Jesus Alvarado-Huayhuaz, Darren Fayne

J Chem Inf Model· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
(
()-1-(3-(3-Hydroxy-4-Methoxyphenyl)-1-(3,4,5-Trimethoxyphenyl)allyl)-1-1,2,4-Triazole and Related Compounds: Their Synthesis and Biological Evaluation as Novel Antimitotic Agents Targeting Breast Cancer.
Gloria Ana, Azizah M Malebari, Sara Noorani, Darren Fayne, Niamh M O'Boyle

Pharmaceuticals (Basel)· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and Biochemical Evaluation of Ethanoanthracenes and Related Compounds: Antiproliferative and Pro-Apoptotic Effects in Chronic Lymphocytic Leukemia (CLL).
James P McKeown, Andrew J Byrne, Sandra A Bright, Clara E Charleton, Shubhangi Kandwal, Darren Fayne

Pharmaceuticals (Basel)· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Respiratory syncytial virus NS1 inhibits anti-viral Interferon-α-induced JAK/STAT signaling, by limiting the nuclear translocation of STAT1.
Claudia Efstathiou, Yamei Zhang, Shubhangi Kandwal, Darren Fayne, Eleanor J Molloy

Front Immunol· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and Pro-Apoptotic Effects of Nitrovinylanthracenes and Related Compounds in Chronic Lymphocytic Leukaemia (CLL) and Burkitt's Lymphoma (BL).
Andrew J Byrne, Sandra A Bright, James P McKeown, Adam Bergin, Brendan Twamley, Darren Fayne

Molecules· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DataPype: A Fully Automated Unified Software Platform for Computer-Aided Drug Design.
Mohemmed Faraz Khan, Shubhangi Kandwal, Darren Fayne

ACS Omega· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells.
Shu Wang, Azizah M Malebari, Thomas F Greene, Shubhangi Kandwal, Darren Fayne

Pharmaceuticals (Basel)· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genetic conservation across SARS-CoV-2 non-structural proteins - Insights into possible targets for treatment of future viral outbreaks.
Shubhangi Kandwal, Darren Fayne

Virology· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mapping of Protein Binding Sites using clustering algorithms - Development of a pharmacophore based drug discovery tool.
Jessica Braun, Darren Fayne

J Mol Graph Model· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis, Characterisation and Mechanism of Action of Anticancer 3-Fluoroazetidin-2-ones.
Azizah M Malebari, Gabriela Duffy Morales, Brendan Twamley, Darren Fayne, Mohemmed Faraz Khan

Pharmaceuticals (Basel)· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Repurposing drugs for treatment of SARS-CoV-2 infection: computational design insights into mechanisms of action.
Shubhangi Kandwal, Darren Fayne

J Biomol Struct Dyn· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and Antiproliferative Evaluation of 3-Chloroazetidin-2-ones with Antimitotic Activity: Heterocyclic Bridged Analogues of Combretastatin A-4.
Azizah M Malebari, Shu Wang, Thomas F Greene, Niamh M O'Boyle, Darren Fayne

Pharmaceuticals (Basel)· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and Biological Evaluation of 1-(Diarylmethyl)-1-1,2,4-triazoles and 1-(Diarylmethyl)-1-imidazoles as a Novel Class of Anti-Mitotic Agent for Activity in Breast Cancer.
Gloria Ana, Patrick M Kelly, Azizah M Malebari, Sara Noorani, Seema M Nathwani, Darren Fayne

Pharmaceuticals (Basel)· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis, Anti-proliferative Activity, and Molecular Docking Study of New Series of 1,3-5-Triazine Schiff Base Derivatives.
Hessa H Al Rasheed, Azizah M Malebari, Kholood A Dahlous, Darren Fayne, Ayman El-Faham

Molecules· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Î
β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells.
Azizah M Malebari, Darren Fayne, Seema M Nathwani, Fiona O'Connell, Sara Noorani

Eur J Med Chem· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design, Synthesis and Biochemical Evaluation of Novel Ethanoanthracenes and Related Compounds to Target Burkitt's Lymphoma.
Andrew J Byrne, Sandra A Bright, James P McKeown, John E O'Brien, Brendan Twamley, Darren Fayne

Pharmaceuticals (Basel)· January 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and evaluation of antiproliferative microtubule-destabilising combretastatin A-4 piperazine conjugates.
Niamh M O'Boyle, Gloria Ana, Patrick M Kelly, Seema M Nathwani, Sara Noorani, Darren Fayne

Org Biomol Chem· June 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
3
3-Vinylazetidin-2-Ones: Synthesis, Antiproliferative and Tubulin Destabilizing Activity in MCF-7 and MDA-MB-231 Breast Cancer Cells.
Shu Wang, Azizah M Malebari, Thomas F Greene, Niamh M O'Boyle, Darren Fayne

Pharmaceuticals (Basel)· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Single point mutations reveal amino acid residues important for Chromobacterium violaceum transaminase activity in the production of unnatural amino acids.
Sarah A Almahboub, Tanja Narancic, Darren Fayne, Kevin E O'Connor

Sci Rep· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis, Antiproliferative and Pro-Apoptotic Effects of Nitrostyrenes and Related Compounds in Burkitt's Lymphoma.
Andrew J Byrne, Sandra A Bright, Darren Fayne, James P McKeown, Thomas McCabe

Med Chem· February 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel Selective Estrogen Receptor Ligand Conjugates Incorporating Endoxifen-Combretastatin and Cyclofenil-Combretastatin Hybrid Scaffolds: Synthesis and Biochemical Evaluation.
Patrick M Kelly, Niall O Keely, Sandra A Bright, Bassem Yassin, Gloria Ana, Darren Fayne

Molecules· August 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis