Publications by authors named "Darren Riley"

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The role of silicon in drug discovery: a review.
Jenny-Lee Panayides, Darren Lyall Riley, Felix Hasenmaile, Willem A L van Otterlo

RSC Med Chem· October 2024

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The in silico and in vitro analysis of donepezil derivatives for Anopheles acetylcholinesterase inhibition.
Thankhoe A Rants'o, Divan G van Greunen, C Johan van der Westhuizen, Darren L Riley, Jenny-Lee Panayides

PLoS One· November 2022

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Discovery of Novel Acetylcholinesterase Inhibitors by Virtual Screening, In Vitro Screening, and Molecular Dynamics Simulations.
C Johan van der Westhuizen, André Stander, Darren L Riley, Jenny-Lee Panayides

J Chem Inf Model· March 2022

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A Molecular-Wide and Electron Density-Based Approach in Exploring Chemical Reactivity and Explicit Dimethyl Sulfoxide (DMSO) Solvent Molecule Effects in the Proline Catalyzed Aldol Reaction.
Ignacy Cukrowski, George Dhimba, Darren L Riley

Molecules· January 2022

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Novel N-benzylpiperidine carboxamide derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease.
Divan G van Greunen, C Johan van der Westhuizen, Werner Cordier, Margo Nell, Andre Stander, Darren L Riley

Eur J Med Chem· October 2019

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A reaction energy profile and fragment attributed molecular system energy change (FAMSEC)-based protocol designed to uncover reaction mechanisms: a case study of the proline-catalysed aldol reaction.
Ignacy Cukrowski, George Dhimba, Darren L Riley

Phys Chem Chem Phys· August 2019

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Mild and selective reduction of aldehydes utilising sodium dithionite under flow conditions.
Nicole C Neyt, Darren L Riley

Beilstein J Org Chem· June 2018

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Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil.
Divan G van Greunen, Werner Cordier, Margo Nell, Chris van der Westhuyzen, Vanessa Steenkamp, Darren L Riley

Eur J Med Chem· February 2017

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New syntheses of (±)-tashiromine and (±)-epitashiromine via enaminone intermediates.
Darren L Riley, Joseph P Michael, Charles B de Koning

Beilstein J Org Chem· December 2016

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Design, synthesis and anticancer activity of Michael-type thiol adducts of α-santonin analogue with exocyclic methylene.
Jabeena Khazir, Darren L Riley, Gousia Chashoo, Bilal Ahmad Mir, David Liles

Eur J Med Chem· August 2015

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Anticancer agents from diverse natural sources.
Jabeena Khazir, Darren L Riley, Lynne A Pilcher, Pieter De-Maayer, Bilal Ahmad Mir

Nat Prod Commun· November 2014

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Preliminary analysis of the nature and processing of palm marks by a U.K. fingerprint bureau.
Raul Sutton, Zoe Glazzard, Darren Riley, Kevan Buckley

J Forensic Sci· November 2013

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