Publications by authors named "Darwin Operario"

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Automated post-run analysis of arrayed quantitative PCR amplification curves using machine learning.
Ben J Brintz, Darwin J Operario, David Garrett Brown, Shanrui Wu, Lan Wang

Gates Open Res· May 2025

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Azithromycin for Bacterial Watery Diarrhea: A Reanalysis of the AntiBiotics for Children With Severe Diarrhea (ABCD) Trial Incorporating Molecular Diagnostics.
Patricia B Pavlinac, James A Platts-Mills, Jie Liu, Hannah E Atlas, Jean Gratz, Darwin Operario

J Infect Dis· April 2024

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Clofazimine pharmacokinetics in HIV-infected adults with diarrhea: Implications of diarrheal disease on absorption of orally administered therapeutics.
Cindy X Zhang, Thomas M Conrad, David Hermann, Melita A Gordon, Eric Houpt, Darwin J Operario

CPT Pharmacometrics Syst Pharmacol· March 2024

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Examination of ELISA against PCR for assessing treatment efficacy against Cryptosporidium in a clinical trial context.
James T Nyirenda, Marc Y R Henrion, Vita Nyasulu, Mike Msakwiza, Wilfred Nedi, Darwin J Operario

PLoS One· September 2023

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Pharmacogenetic testing for NAT2 genotypes in a Tanzanian population across the lifespan to guide future personalized isoniazid dosing.
Maano V Masiphephethu, Margaretha Sariko, Thomas Walongo, Athanasia Maro, Dorcus Mduma, Darwin J Operario

Tuberculosis (Edinb)· September 2022

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Aetiology and incidence of diarrhoea requiring hospitalisation in children under 5 years of age in 28 low-income and middle-income countries: findings from the Global Pediatric Diarrhea Surveillance network.
Adam L Cohen, James A Platts-Mills, Tomoka Nakamura, Darwin J Operario, Sébastien Antoni

BMJ Glob Health· September 2022

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The positive effect of malaria IPTp-SP on birthweight is mediated by gestational weight gain but modifiable by maternal carriage of enteric pathogens.
Andreea Waltmann, Elizabeth T Rogawski McQuade, Jobiba Chinkhumba, Darwin J Operario, Enala Mzembe

EBioMedicine· March 2022

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Pathogens That Cause Acute Febrile Illness Among Children and Adolescents in Burkina Faso, Madagascar, and Sudan.
Florian Marks, Jie Liu, Abdramane Bassiahi Soura, Nagla Gasmelseed, Darwin J Operario

Clin Infect Dis· October 2021

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The Clinical Presentation of Culture-positive and Culture-negative, Quantitative Polymerase Chain Reaction (qPCR)-Attributable Shigellosis in the Global Enteric Multicenter Study and Derivation of a Shigella Severity Score: Implications for Pediatric Shigella Vaccine Trials.
Patricia B Pavlinac, James A Platts-Mills, Kirkby D Tickell, Jie Liu, Jane Juma, Darwin J Operario

Clin Infect Dis· August 2021

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Assessment of Seroprevalence of SARS-CoV-2 and Risk Factors Associated With COVID-19 Infection Among Outpatients in Virginia.
Elizabeth T Rogawski McQuade, Kristin A Guertin, Lea Becker, Darwin Operario, Jean Gratz

JAMA Netw Open· February 2021

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Surveillance of Plasmodium falciparum pfcrt haplotypes in southwestern uganda by high-resolution melt analysis.
Kennedy Kassaza, Anna C Long, Jennifer M McDaniels, Mharlove Andre, Wasswa Fredrickson, Darwin J Operario

Malar J· February 2021

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Seasonality of drinking water sources and the impact of drinking water source on enteric infections among children in Limpopo, South Africa.
Kathy H Nguyen, Darwin J Operario, Mzwakhe E Nyathi, Courtney L Hill, James A Smith

Int J Hyg Environ Health· January 2021

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Impact of Low-Cost Point-of-Use Water Treatment Technologies on Enteric Infections and Growth among Children in Limpopo, South Africa.
Courtney L Hill, Kelly McCain, Mzwakhe E Nyathi, Joshua N Edokpayi, David M Kahler, Darwin J Operario

Am J Trop Med Hyg· October 2020

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Complex Diversity within Lung Disease, as Revealed by Whole-Genome Sequencing.
Darwin J Operario, Suporn Pholwat, Alex F Koeppel, Alyson Prorock, Yongde Bao

Am J Respir Crit Care Med· August 2019

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Etiology of Diarrhea Among Hospitalized Children in Blantyre, Malawi, Following Rotavirus Vaccine Introduction: A Case-Control Study.
Miren Iturriza-Gómara, Khuzwayo C Jere, Daniel Hungerford, Naor Bar-Zeev, Kayoko Shioda, Darwin J Operario

J Infect Dis· June 2019

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Use of quantitative molecular diagnostic methods to investigate the effect of enteropathogen infections on linear growth in children in low-resource settings: longitudinal analysis of results from the MAL-ED cohort study.
Elizabeth T Rogawski, Jie Liu, James A Platts-Mills, Furqan Kabir, Paphavee Lertsethtakarn, Darwin J Operario

Lancet Glob Health· December 2018

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Use of quantitative molecular diagnostic methods to assess the aetiology, burden, and clinical characteristics of diarrhoea in children in low-resource settings: a reanalysis of the MAL-ED cohort study.
James A Platts-Mills, Jie Liu, Elizabeth T Rogawski, Furqan Kabir, Paphavee Lertsethtakarn, Darwin J Operario

Lancet Glob Health· December 2018

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Detection of Dengue Virus among Children with Suspected Malaria, Accra, Ghana.
Nicholas Amoako, Samuel Duodu, Francis E Dennis, Joseph H K Bonney, Kwaku P Asante, Darwin J Operario

Emerg Infect Dis· August 2018

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Detection of Plasmodium Species by High-Resolution Melt Analysis of DNA from Blood Smears Acquired in Southwestern Uganda.
Kennedy Kassaza, Darwin J Operario, Dan Nyehangane, K C Coffey, Mary Namugosa

J Clin Microbiol· January 2018

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Influence of the intestinal microbiota on the immunogenicity of oral rotavirus vaccine given to infants in south India.
Edward P K Parker, Ira Praharaj, Anna Zekavati, Robin P Lazarus, Sidhartha Giri, Darwin J Operario

Vaccine· January 2018

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Prevalence and extent of heteroresistance by next generation sequencing of multidrug-resistant tuberculosis.
Darwin J Operario, Alexander F Koeppel, Stephen D Turner, Yongde Bao, Suporn Pholwat

PLoS One· September 2017

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Investigating the Adult Ixodid Tick Populations and Their Associated Anaplasma, Ehrlichia, and Rickettsia Bacteria at a Rocky Mountain Spotted Fever Hotspot in Western Tennessee.
Rebecca T Trout Fryxell, Brain M Hendricks, Kimberly Pompo, Sarah E Mays, Dave J Paulsen, Darwin J Operario

Vector Borne Zoonotic Dis· August 2017

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Correction: Prevalence and extent of heteroresistance by next generation sequencing of multidrug-resistant tuberculosis.
Darwin J Operario, Alexander F Koeppel, Stephen D Turner, Yongde Bao, Suporn Pholwat

PLoS One· July 2017

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Etiology of Severe Acute Watery Diarrhea in Children in the Global Rotavirus Surveillance Network Using Quantitative Polymerase Chain Reaction.
Darwin J Operario, James A Platts-Mills, Sandrama Nadan, Nicola Page, Mapaseka Seheri

J Infect Dis· July 2017

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Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study.
Jie Liu, James A Platts-Mills, Jane Juma, Furqan Kabir, Joseph Nkeze, Darwin J Operario

Lancet· September 2016

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