Publications by authors named "Daryl Murry"

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Discovery of a "First-in-Class" Selective Multikinase (CDK4/6/9-AURKA/B) Inhibitor, LCI133, for Neuroblastoma.
Krishnaiah Maddeboina, Dhananjaya Pal, Bharath Yada, Cody C McHale, Sandeep K Singh, Daryl J Murry

J Med Chem· November 2025

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Reactive Oxygen Species-Responsive Polymeric Chloroquine Nanogel for Targeted Oral Therapy of Ulcerative Colitis.
Neha Kumari, Sudipta Panja, Balawant Kumar, Rizwan Ahmad, Sai Sundeep Kollala, Daryl J Murry

ACS Appl Mater Interfaces· September 2025

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Further Structure-Activity Relationship of G Protein-Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool Compounds.
Sumaiya Nahid, Fahad Imtiaz Rahman, Yu Du, Brittany D Spitznagel, Sandeep K Singh, Daryl J Murry

ChemMedChem· July 2025

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Antimicrobial peptide developed with machine learning sequence optimization targets drug resistant Staphylococcus aureus in mice.
Biswajit Mishra, Anindya Basu, Fadi Shehadeh, LewisOscar Felix, Sai Sundeep Kollala, Daryl J Murry

J Clin Invest· June 2025

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Impact of fixed phosphorus position on activity of triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors.
Md Ayub Ali, Mona A Maalouf, Dan Feng, Mamunur Rashid, Nathaniel R Gehrke, Daryl J Murry

Bioorg Med Chem· May 2025

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Crossing the Blood-Brain Barrier: Innovations in Receptor- and Transporter-Mediated Transcytosis Strategies.
Ling Ding, Pratiksha Kshirsagar, Prachi Agrawal, Daryl J Murry

Pharmaceutics· May 2025

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Identification of Potential Prophylactic Medical Countermeasures Against Acute Radiation Syndrome (ARS).
Kia T Liermann-Wooldrik, Arpita Chatterjee, Elizabeth A Kosmacek, Molly S Myers, Oluwaseun Adebisi, Daryl J Murry

Int J Mol Sci· April 2025

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Coenzyme Q deficiency disrupts lipid metabolism by altering cholesterol homeostasis in neurons.
Alba Pesini, Eliana Barriocanal-Casado, Giacomo Monzio Compagnoni, Agustin Hidalgo-Gutierrez, Giussepe Yanez, Daryl J Murry

Free Radic Biol Med· March 2025

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Structure-activity relationship of isoprenoid triazole bisphosphonate-based geranylgeranyl diphosphate synthase inhibitors: Effects on pharmacokinetics, biodistribution, and hepatic transporters.
Staci L Haney, Yashpal S Chhonker, Mamunur Rashid, Daryl J Murry, Sarah A Holstein

Drug Metab Dispos· March 2025

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Geranylgeranyl diphosphate synthase inhibition impairs osteoclast differentiation, morphology, and resorptive activity.
Molly E Muehlebach, Staci L Haney, Yashpal S Chhonker, Mamunur Rashid, Daryl J Murry

JBMR Plus· January 2025

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Feeding intolerance after pediatric cardiac surgery is associated with dysbiosis, barrier dysfunction, and reduced short-chain fatty acids.
Jacob Owens, Haowen Qiu, Cole Knoblich, Lisa Gerjevic, Jacques Izard, Daryl J Murry

Am J Physiol Gastrointest Liver Physiol· November 2024

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Development and Validation of an LC-MS/MS Assay for the Quantitation of MO-OH-Nap Tropolone in Mouse Plasma: Application to In Vitro and In Vivo Pharmacokinetic Studies.
Wafaa N Aldhafiri, Yashpal S Chhonker, Nusrat Ahmed, Sandeep K Singh, Staci L Haney, Daryl J Murry

Molecules· September 2024

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Polymer-Based Drug Delivery Systems for Cancer Therapeutics.
Ling Ding, Prachi Agrawal, Sandeep K Singh, Yashpal S Chhonker, Jingjing Sun, Daryl J Murry

Polymers (Basel)· March 2024

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Investigation of the activity of a novel tropolone in osteosarcoma.
Staci L Haney, Dan Feng, Sai Sundeep Kollala, Yashpal S Chhonker, Michelle L Varney, Daryl J Murry

Drug Dev Res· February 2024

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Blood-stage antimalarial activity, favourable metabolic stability and in vivo toxicity of novel piperazine linked 7-chloroquinoline-triazole conjugates.
Amad Uddin, Sonal Gupta, Rumaisha Shoaib, Babita Aneja, Iram Irfan, Daryl J Murry

Eur J Med Chem· January 2024

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Marinopyrrole derivative MP1 as a novel anti-cancer agent in group 3 MYC-amplified Medulloblastoma.
Don W Coulter, Yashpal S Chhonker, Devendra Kumar, Varun Kesherwani, Wafaa N Aldhafiri, Daryl J Murry

J Exp Clin Cancer Res· January 2024

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Repeated Social Defeat Stress Induces an Inflammatory Gut Milieu by Altering the Mucosal Barrier Integrity and Gut Microbiota Homeostasis.
Santosh K Yadav, Rizwan Ahmad, Cassandra M Moshfegh, Jagadesan Sankarasubramanian, Vineet Joshi, Daryl J Murry

Biol Psychiatry Glob Open Sci· October 2023

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Simultaneous LC-MS/MS method for the quantitation of Azithromycin, Hydroxychloroquine and its metabolites in SARS-CoV-2(-/ +) populations using dried blood spots.
Yashpal S Chhonker, Wafaa N Aldhafiri, Dhruvkumar Soni, Neerja Trivedi, Claire Steinbronn, Daryl J Murry

Sci Rep· September 2023

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LC-MS/MS method for the quantitation of a dual PI3K/BRD4 inhibitor SF2523 in mouse plasma: Application to plasma protein binding and metabolism studies.
Veenu Bala, Yashpal S Chhonker, Guillermo A Morales, Krishnaiah Maddeboina, Dhananjaya Pal, Daryl J Murry

Biomed Chromatogr· August 2023

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Pharmacokinetics of Moxidectin combined with Albendazole or Albendazole plus Diethylcarbamazine for Bancroftian Filariasis.
Yashpal S Chhonker, Catherine Bjerum, Veenu Bala, Allassane F Ouattara, Benjamin G Koudou, Daryl J Murry

PLoS Negl Trop Dis· August 2023

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A linked physiologically based pharmacokinetic model for hydroxychloroquine and metabolite desethylhydroxychloroquine in SARS-CoV-2(-)/(+) populations.
Claire Steinbronn, Yashpal S Chhonker, Jenell Stewart, Hannah Leingang, Kate B Heller, Daryl J Murry

Clin Transl Sci· July 2023

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Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model.
Krishnaiah Maddeboina, Sravan K Jonnalagadda, Ahmed Morsy, Ling Duan, Yashpal S Chhonker, Daryl J Murry

J Med Chem· July 2023

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Population pharmacokinetic model of ivermectin in mass drug administration against lymphatic filariasis.
Abdullah Alshehri, Yashpal S Chhonker, Veenu Bala, Constant Edi, Catherine M Bjerum, Daryl J Murry

PLoS Negl Trop Dis· June 2023

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Disentangling the links between gastric emptying and binge eating . purging in eating disorders using a case-control design.
Pamela K Keel, Lisa A Eckel, Britny A Hildebrandt, Alissa A Haedt-Matt, Daryl J Murry

Psychol Med· April 2023

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A Simultaneous Extraction/Derivatization Strategy for Quantitation of Vitamin D in Dried Blood Spots Using LC-MS/MS: Application to Biomarker Study in Subjects Tested for SARS-CoV-2.
Yashpal S Chhonker, Nusrat Ahmed, Christine M Johnston, Ruanne V Barnabas, Daryl J Murry

Int J Mol Sci· March 2023

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