Publications by authors named "David A Barbie"

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Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancer.
Deli Hong, Ying Lyu, Richa Nayak, Justin S Becker, Matthew A Booker, David A Barbie

Dev Cell· December 2025

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Dipeptidyl Peptidase 4 Restoration Facilitates Antitumor Immunity in KRAS-LKB1-Mutant Lung Cancer.
Toshiyuki Tenma, Ryohei Yoshida, Hiraku Yanada, Kiichi Nitanai, Toshihiro Nagato, David A Barbie

Cancer Res Commun· December 2025

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Presenting Features and Causes of Diagnostic Delays: A Report From the NUT Carcinoma Registry.
Sara A Walton, Justin J Kim, Francesco Paoloni, Jean W Liew, Danielle Haradon, David A Barbie

JCO Precis Oncol· December 2025

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Targeting STING to generate therapeutic anti-tumor immunity.
Caroline G Fahey, Anthony F Cordova, Patrick C Gedeon, David A Barbie

Cancer Cell· December 2025

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Eradicating Drug-tolerant Persister Cells in EGFR-Mutated Non-Small Cell Lung Cancer by Targeting TROP2 with CAR-T Cellular Therapy.
Simon Baldacci, Elliott J Brea, Francesco Facchinetti, Zhaorong Li, Kenneth Ngo, David A Barbie

Cancer Discov· November 2025

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Systematic Engineering of TROP2-Targeted CAR T-Cell Therapy Overcomes Resistance Pathways in Solid Tumors.
Elliott J Brea, Simon Baldacci, Neil Savage, Francesco Facchinetti, Conor Hinchey, Thanh U Barbie, David A Barbie

Cancer Immunol Res· November 2025

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Cancers modulate p53 truncal neoantigen display to evade T cell detection.
Koji Haratani, Bruce Reinhold, Jonathan S Duke-Cohan, Caroline G Fahey, Kemin Tan, David A Barbie

bioRxiv· November 2025

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Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor that Unleashes PD-1 Checkpoint and CAR T-cell Immunotherapies.
Michael Wichroski, Si-Qi Liu, Lauren M Zasadil, Joseph L Benci, Patrick C Gedeon, Christopher M Barbieri, David A Barbie

Cancer Immunol Res· September 2025

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Molecular Characterization of NUT Carcinoma: A Report from the NUT Carcinoma Registry.
Justin J Kim, Sara A Walton, Navin R Mahadevan, Jessica Haradon, Francesco Paoloni, David A Barbie

Clin Cancer Res· September 2025

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Immune targeting of triple-negative breast cancer through a clinically actionable STING agonist-CAR T cell platform.
Yuqing Zhang, Zehua Li, Jessica Ritter, Elliott J Brea, Navin R Mahadevan, David A Barbie, Thanh U Barbie

Cell Rep Med· July 2025

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RNA sensing induced by chromosome missegregation augments anti-tumor immunity.
Nobunari Sasaki, Mizuki Homme, Takahiko Murayama, Tatsuya Osaki, Toshiyuki Tenma, David A Barbie

Mol Cell· February 2025

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Phase I/II Investigator-Initiated Study of Olaparib and Temozolomide in SCLC: Final Analysis and CNS Outcomes.
Catherine B Meador, Subba R Digumarthy, Beow Y Yeap, Yin P Hung, Mari Mino-Kenudson, David A Barbie

Clin Cancer Res· January 2025

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Myofibroblasts reduce angiogenesis and vasculogenesis in a vascularized microphysiological model of lung fibrosis.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A Barbie

bioRxiv· January 2025

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Dual Immune Checkpoint Inhibition in Patients With Aggressive Thyroid Carcinoma: A Phase 2 Nonrandomized Clinical Trial.
Kartik Sehgal, Theodora Pappa, Kee-Young Shin, Julia Schiantarelli, Mofei Liu, David A Barbie

JAMA Oncol· December 2024

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AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution.
Amy E Schade, Naiara Perurena, Yoona Yang, Carrie L Rodriguez, Anjana Krishnan, David A Barbie

Nature· November 2024

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miR126-mediated impaired vascular integrity in Rett syndrome.
Tatsuya Osaki, Zhengpeng Wan, Koji Haratani, Ylliah Jin, Marco Campisi, David A Barbie

bioRxiv· October 2024

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Detecting Small Cell Transformation in Patients with Advanced EGFR Mutant Lung Adenocarcinoma through Epigenomic cfDNA Profiling.
Talal El Zarif, Catherine B Meador, Xintao Qiu, Ji-Heui Seo, Matthew P Davidsohn, David A Barbie

Clin Cancer Res· September 2024

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Targeting TREX1 Induces Innate Immune Response in Drug-Resistant Small-Cell Lung Cancer.
Takahiko Murayama, Navin R Mahadevan, Catherine B Meador, Elena V Ivanova, Yuqiao Pan, David A Barbie

Cancer Res Commun· September 2024

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Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes.
Varadha Balaji Venkadakrishnan, Adam G Presser, Richa Singh, Matthew A Booker, Nicole A Traphagen, David A Barbie

Nat Commun· August 2024

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Transmural Flow Upregulates PD-L1 Expression in Microvascular Networks.
Zhengpeng Wan, Shun Zhang, Amy X Zhong, Liling Xu, Mark F Coughlin, David A Barbie

Adv Sci (Weinh)· July 2024

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CAR memory-like NK cells targeting the membrane proximal domain of mesothelin demonstrate promising activity in ovarian cancer.
Mubin Tarannum, Khanhlinh Dinh, Juliana Vergara, Grace Birch, Yasmin Z Abdulhamid, David A Barbie

Sci Adv· July 2024

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TREX1 Inactivation Unleashes Cancer Cell STING-Interferon Signaling and Promotes Antitumor Immunity.
Tetsuo Tani, Haritha Mathsyaraja, Marco Campisi, Ze-Hua Li, Koji Haratani, Thanh U Barbie, David A Barbie

Cancer Discov· May 2024

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Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes.
Varadha Balaji Venkadakrishnan, Adam G Presser, Richa Singh, Matthew A Booker, Nicole A Traphagen, David A Barbie

Res Sq· March 2024

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Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects.
Yufei Wang, Alicia Buck, Brandon Piel, Luann Zerefa, Nithyassree Murugan, David A Barbie

Mol Cancer· March 2024

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Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers.
Olli Dufva, Sara Gandolfi, Jani Huuhtanen, Olga Dashevsky, Hanna Duàn, David A Barbie

Immunity· December 2023

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